Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment M Elahy, C Jackaman, JCL Mamo, V Lam, SS Dhaliwal, C Giles, D Nelson, ... Immunity & Ageing 12, 1-9, 2015 | 305 | 2015 |
Blood-brain barrier dysfunction precedes cognitive decline and neurodegeneration in diabetic insulin resistant mouse model: an implication for causal link R Takechi, V Lam, E Brook, C Giles, N Fimognari, A Mooranian, ... Frontiers in aging neuroscience 9, 399, 2017 | 141 | 2017 |
A systematic review of the valproic-acid-induced rodent model of autism D Chaliha, M Albrecht, M Vaccarezza, R Takechi, V Lam, H Al-Salami, ... Developmental neuroscience 42 (1), 12-48, 2020 | 116 | 2020 |
Impaired postprandial apolipoprotein-B48 metabolism in the obese, insulin-resistant JCR: LA-cp rat: increased atherogenicity for the metabolic syndrome DF Vine, R Takechi, JC Russell, SD Proctor Atherosclerosis 190 (2), 282-290, 2007 | 110 | 2007 |
Dietary fats, cerebrovasculature integrity and Alzheimer’s disease risk R Takechi, S Galloway, MMS Pallebage-Gamarallage, V Lam, JCL Mamo Progress in lipid research 49 (2), 159-170, 2010 | 100 | 2010 |
Differential effects of dietary fatty acids on the cerebral distribution of plasma-derived apo B lipoproteins with amyloid-β R Takechi, S Galloway, MMS Pallebage-Gamarallage, CL Wellington, ... British journal of nutrition 103 (5), 652-662, 2010 | 79 | 2010 |
Aging-related changes in blood-brain barrier integrity and the effect of dietary fat R Takechi, MM Pallebage-Gamarallage, V Lam, C Giles, JC Mamo Neurodegenerative Diseases 12 (3), 125-135, 2013 | 72 | 2013 |
Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood–brain barrier function in wild-type mice R Takechi, MM Pallebage-Gamarallage, V Lam, C Giles, JC Mamo Journal of neuroinflammation 10, 1-12, 2013 | 68 | 2013 |
Synthesis of human amyloid restricted to liver results in an Alzheimer disease–like neurodegenerative phenotype V Lam, R Takechi, MJ Hackett, R Francis, M Bynevelt, LM Celliers, ... PLoS biology 19 (9), e3001358, 2021 | 61 | 2021 |
A multimodal spectroscopic imaging method to characterize the metal and macromolecular content of proteinaceous aggregates (“amyloid plaques”) KL Summers, N Fimognari, A Hollings, M Kiernan, V Lam, RJ Tidy, ... Biochemistry 56 (32), 4107-4116, 2017 | 60 | 2017 |
Probucol prevents blood–brain barrier dysfunction in wild‐type mice induced by saturated fat or cholesterol feeding R Takechi, S Galloway, MM Pallebage‐Gamarallage, V Lam, SS Dhaliwal, ... Clinical and Experimental Pharmacology and Physiology 40 (1), 45-52, 2013 | 58 | 2013 |
Biotin deficiency affects the proliferation of human embryonic palatal mesenchymal cells in culture R Takechi, A Taniguchi, S Ebara, T Fukui, T Watanabe The Journal of nutrition 138 (4), 680-684, 2008 | 58 | 2008 |
Restoration of dietary-fat induced blood–brain barrier dysfunction by anti-inflammatory lipid-modulating agents M Pallebage-Gamarallage, V Lam, R Takechi, S Galloway, K Clark, ... Lipids in health and disease 11, 1-11, 2012 | 56 | 2012 |
Chylomicron amyloid-beta in the aetiology of Alzheimer's disease R Takechi, S Galloway, MMS Pallebage-Gamarallage, JCL Mamo Atherosclerosis Supplements 9 (2), 19-25, 2008 | 54 | 2008 |
Probucol prevents blood–brain barrier dysfunction and cognitive decline in mice maintained on pro-diabetic diet JCL Mamo, V Lam, E Brook, A Mooranian, H Al-Salami, N Fimognari, ... Diabetes and Vascular Disease Research 16 (1), 87-97, 2019 | 51 | 2019 |
Bile acid bio-nanoencapsulation improved drug targeted-delivery and pharmacological effects via cellular flux: 6-months diabetes preclinical study A Mooranian, S Raj Wagle, B Kovacevic, R Takechi, J Mamo, V Lam, ... Scientific Reports 10 (1), 106, 2020 | 50 | 2020 |
The effect of diesel exhaust exposure on blood–brain barrier integrity and function in a murine model S Heidari Nejad, R Takechi, BJ Mullins, C Giles, AN Larcombe, ... Journal of Applied Toxicology 35 (1), 41-47, 2015 | 48 | 2015 |
Amyloid-β colocalizes with apolipoprotein B in absorptive cells of the small intestine S Galloway, R Takechi, MMS Pallebage-Gamarallage, SS Dhaliwal, ... Lipids in health and disease 8, 1-7, 2009 | 46 | 2009 |
Three-dimensional colocalization analysis of plasma-derived apolipoprotein B with amyloid plaques in APP/PS1 transgenic mice R Takechi, S Galloway, M Pallebage-Gamarallage, C Wellington, ... Histochemistry and cell biology 131, 661-666, 2009 | 46 | 2009 |
The effects of long-term saturated fat enriched diets on the brain lipidome C Giles, R Takechi, NA Mellett, PJ Meikle, S Dhaliwal, JC Mamo PloS one 11 (12), e0166964, 2016 | 45 | 2016 |