A cell-free DNA metagenomic sequencing assay that integrates the host injury response to infection AP Cheng, P Burnham, JR Lee, MP Cheng, M Suthanthiran, D Dadhania, ... Proceedings of the National Academy of Sciences 116 (37), 18738-18744, 2019 | 70 | 2019 |
Cell-free DNA tissues of origin by methylation profiling reveals significant cell, tissue, and organ-specific injury related to COVID-19 severity AP Cheng, MP Cheng, W Gu, JS Lenz, E Hsu, E Schurr, G Bourque, ... Med 2 (4), 411-422. e5, 2021 | 66* | 2021 |
Lysosomal rupture induced by structurally distinct chitosans either promotes a type 1 IFN response or activates the inflammasome in macrophages D Fong, P Grégoire-Gélinas, AP Cheng, T Mezheritsky, M Lavertu, S Sato, ... Biomaterials 129, 127-138, 2017 | 65 | 2017 |
Back to the future: penicillin-susceptible Staphylococcus aureus MP Cheng, P René, AP Cheng, TC Lee The American Journal of Medicine 129 (12), 1331-1333, 2016 | 51 | 2016 |
Separating the signal from the noise in metagenomic cell-free DNA sequencing P Burnham, N Gomez-Lopez, M Heyang, AP Cheng, JS Lenz, ... Microbiome 8, 1-9, 2020 | 38 | 2020 |
Cell-free DNA profiling informs all major complications of hematopoietic cell transplantation AP Cheng, MP Cheng, CJ Loy, JS Lenz, K Chen, S Smalling, P Burnham, ... Proceedings of the National Academy of Sciences 119 (4), e2113476118, 2022 | 34 | 2022 |
Beta-lactam/beta-lactamase inhibitor therapy for potential AmpC-producing organisms: a systematic review and meta-analysis MP Cheng, RS Lee, AP Cheng, S De L’Étoile-Morel, K Demir, ... Open forum infectious diseases 6 (7), ofz248, 2019 | 22 | 2019 |
A metagenomic DNA sequencing assay that is robust against environmental DNA contamination O Mzava, AP Cheng, A Chang, S Smalling, LAK Djomnang, JS Lenz, ... Nature Communications 13 (1), 4197, 2022 | 15 | 2022 |
Using MRSA screening tests to predict methicillin resistance in Staphylococcus aureus bacteremia G Butler-Laporte, MP Cheng, AP Cheng, EG McDonald, TC Lee Antimicrobial Agents and Chemotherapy 60 (12), 7444-7448, 2016 | 14 | 2016 |
Machine learning guided signal enrichment for ultrasensitive plasma tumor burden monitoring AJ Widman, M Shah, N Øgaard, CC Khamnei, A Frydendahl, ... bioRxiv, 2022.01. 17.476508, 2022 | 10 | 2022 |
Separating the signal from the noise in metagenomic cell-free DNA sequencing. Microbiome 8 18 P Burnham, N Gomez-Lopez, M Heyang, AP Cheng, JS Lenz, ... | 8 | 2020 |
Nucleic acid biomarkers of immune response and cell and tissue damage in children with COVID-19 and MIS-C CJ Loy, A Sotomayor-Gonzalez, V Servellita, J Nguyen, J Lenz, ... Cell Reports Medicine 4 (6), 2023 | 7 | 2023 |
Measurement biases distort cell-free DNA fragmentation profiles and define the sensitivity of metagenomic cell-free DNA sequencing assays A Chang, O Mzava, JS Lenz, AP Cheng, P Burnham, ST Motley, ... Clinical Chemistry 68 (1), 163-171, 2022 | 6 | 2022 |
Peritoneal effluent cell-free DNA sequencing in peritoneal dialysis patients with and without peritonitis P Burnham, F Chen, AP Cheng, V Srivatana, LT Zhang, E Edusei, ... Kidney Medicine 4 (1), 100383, 2022 | 4 | 2022 |
Whole genome error-corrected sequencing for sensitive circulating tumor DNA cancer monitoring AP Cheng, AJ Widman, A Arora, I Rusinek, WF Hooper, R Murray, ... bioRxiv, 2022.11. 17.516904, 2022 | 2 | 2022 |
Biopsy‐free screening for glioma AP Cheng, P Burnham, I De Vlaminck EMBO molecular medicine 10 (12), e9484, 2018 | 2 | 2018 |
UDP-glucose dehydrogenase (UGDH) activity is suppressed by peroxide and promoted by PDGF in fibroblast-like synoviocytes: Evidence of a redox control mechanism R Chandrasekaran, C Mathieu, R Sheth, AP Cheng, D Fong, ... Plos one 17 (9), e0274420, 2022 | 1 | 2022 |
Lightning does strike twice: leveraging phased variants to enhance minimal residual disease detection AP Cheng, DA Landau Med 2 (10), 1114-1116, 2021 | 1 | 2021 |
Relationship of UDP-glucose dehydrogenase activity and in vitro hyaluronic acid release by human fibroblast-like synoviocytes C Mathieu, AP Cheng, D Fong, K Diab, R Mccormack, H El Gabalawy, ... Frontiers in Bioengineering and Biotechnology, 1-2, 2016 | 1 | 2016 |
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment AJ Widman, M Shah, A Frydendahl, D Halmos, CC Khamnei, N Øgaard, ... Nature Medicine, 1-12, 2024 | | 2024 |