| Effects of a MATE protein inhibitor, pyrimethamine, on the renal elimination of metformin at oral microdose and at therapeutic dose in healthy subjects H Kusuhara, S Ito, Y Kumagai, M Jiang, T Shiroshita, Y Moriyama, K Inoue, ... Clinical Pharmacology & Therapeutics 89 (6), 837-844, 2011 | 251 | 2011 |
| Competitive Inhibition of the Luminal Efflux by Multidrug and Toxin Extrusions, but Not Basolateral Uptake by Organic Cation Transporter 2, Is the Likely Mechanism Underlying … S Ito, H Kusuhara, M Yokochi, J Toyoshima, K Inoue, H Yuasa, ... Journal of Pharmacology and Experimental Therapeutics 340 (2), 393-403, 2012 | 235 | 2012 |
| Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine S Ito, H Kusuhara, Y Kuroiwa, C Wu, Y Moriyama, K Inoue, T Kondo, ... Journal of Pharmacology and Experimental Therapeutics 333 (1), 341-350, 2010 | 160 | 2010 |
| N‐Methylnicotinamide Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving Multidrug and Toxin Extrusions (MATE1 and MATE2‐K) S Ito, H Kusuhara, Y Kumagai, Y Moriyama, K Inoue, T Kondo, ... Clinical Pharmacology & Therapeutics 92 (5), 635-641, 2012 | 107 | 2012 |
| Investigation of endogenous compounds for assessing the drug interactions in the urinary excretion involving multidrug and toxin extrusion proteins K Kato, H Mori, T Kito, M Yokochi, S Ito, K Inoue, A Yonezawa, T Katsura, ... Pharmaceutical research 31, 136-147, 2014 | 59 | 2014 |
| The ATP-binding cassette transporter BCRP1/ABCG2 plays a pivotal role in cardiac repair after myocardial infarction via modulation of microvascular endothelial cell survival … Y Higashikuni, J Sainz, K Nakamura, M Takaoka, S Enomoto, H Iwata, ... Arteriosclerosis, thrombosis, and vascular biology 30 (11), 2128-2135, 2010 | 56 | 2010 |
| Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2–Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion … H Liu, N Yu, S Lu, S Ito, X Zhang, B Prasad, E He, X Lu, Y Li, F Wang, ... Drug Metabolism and Disposition 43 (7), 1008-1018, 2015 | 50 | 2015 |
| Generation of human iPSC–derived intestinal epithelial cell monolayers by CDX2 transduction K Takayama, R Negoro, T Yamashita, K Kawai, M Ichikawa, T Mori, ... Cellular and molecular gastroenterology and hepatology 8 (3), 513-526, 2019 | 48 | 2019 |
| Relationship between the urinary excretion mechanisms of drugs and their physicochemical properties S Ito, H Ando, A Ose, Y Kitamura, T Ando, H Kusuhara, Y Sugiyama Journal of Pharmaceutical Sciences 102 (9), 3294-3301, 2013 | 26 | 2013 |
| Drugs interacting with organic anion transporter-1 affect uptake of Tc-99m-mercaptoacetyl-triglycine (MAG3) in the human kidney: therapeutic drug interaction in Tc-99m-MAG3 … N Takahara, T Saga, M Inubushi, H Kusuhara, C Seki, S Ito, N Oyama, ... Nuclear Medicine and Biology 40 (5), 643-650, 2013 | 25 | 2013 |
| Possible role of organic cation transporters in the distribution of [11C] sulpiride, a dopamine D2 receptor antagonist H Takano, S Ito, X Zhang, H Ito, MR Zhang, H Suzuki, K Maeda, ... Journal of pharmaceutical sciences 106 (9), 2558-2565, 2017 | 24 | 2017 |
| Association of multidrug resistance-associated protein 2 single nucleotide polymorphism rs12762549 with the basal plasma levels of phase II metabolites of isoflavonoids in … K Kato, H Kusuhara, Y Kumagai, I Ieiri, H Mori, S Ito, Y Nakai, K Maeda, ... Pharmacogenetics and genomics 22 (5), 344-354, 2012 | 20 | 2012 |
| Different involvement of OAT in renal disposition of oral anticoagulants rivaroxaban, dabigatran, and apixaban Y Tsuruya, T Nakanishi, H Komori, X Wang, N Ishiguro, T Kito, K Ikukawa, ... Journal of Pharmaceutical Sciences 106 (9), 2524-2534, 2017 | 10 | 2017 |
| An international asset map of clinicians, educators, and researchers pursuing better medicine use in children: initial findings SM MacLeod, MJE Greff, DC Knoppert, S Ito, MJ Rieder Clinical Pharmacology & Therapeutics 101 (2), 274-280, 2017 | 10 | 2017 |
| Investigation of non-linear Mate1-mediated efflux of trimethoprim in the mouse kidney as the mechanism underlying drug-drug interactions between trimethoprim and organic … T Kito, S Ito, T Mizuno, K Maeda, H Kusuhara Drug Metabolism and Pharmacokinetics 34 (1), 87-94, 2019 | 9 | 2019 |
| Transient, tunable expression of NTCP and BSEP in MDCKII cells for kinetic delineation of the rate-determining process and inhibitory effects of rifampicin in hepatobiliary … S Ito, W Lee, JE Park, M Yasunaga, A Mori, S Ohtsuki, Y Sugiyama Journal of Pharmaceutical Sciences 110 (1), 365-375, 2021 | 8 | 2021 |
| Comparison of hyphal growth and defense responses in four Fagaceae species inoculated with Raffaelea quercivora. M Murata, T Yamada, Y Matsuda, S Ito | 6 | 2011 |
| Generation of tetracycline-controllable CYP3A4-expressing Caco-2 cells by the piggyBac transposon system M Ichikawa, H Akamine, M Murata, S Ito, K Takayama, H Mizuguchi Scientific Reports 11 (1), 11670, 2021 | 5 | 2021 |
| Competitive inhibition of the luminal efflux by MATEs, but not basolateral uptake by OCT2, is the likely mechanism underlying the pharmacokinetic drug–drug interactions caused … S Ito, H Kusuhara, M Yokochi, J Toyoshima, K Inoue, H Yuasa, ... Journal of Pharmacology and Experimental Therapeutics, 2011 | 5 | 2011 |
| Evaluation of [11C]oseltamivir uptake into the brain during immune activation by systemic polyinosine-polycytidylic acid injection: a quantitative PET study using … C Seki, A Oh-Nishi, Y Nagai, T Minamimoto, S Obayashi, M Higuchi, ... EJNMMI research 4, 1-10, 2014 | 3 | 2014 |
