Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver ME Fusakio, JA Willy, Y Wang, ET Mirek, RJT Al Baghdadi, CM Adams, ... Molecular biology of the cell 27 (9), 1536-1551, 2016 | 228 | 2016 |
CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis JA Willy, SK Young, JL Stevens, HC Masuoka, RC Wek Molecular biology of the cell 26 (12), 2190-2204, 2015 | 136 | 2015 |
Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα TD Baird, LR Palam, ME Fusakio, JA Willy, CM Davis, JN McClintick, ... Molecular biology of the cell 25 (10), 1686-1697, 2014 | 132 | 2014 |
Ribosome reinitiation directs gene-specific translation and regulates the integrated stress response SK Young, JA Willy, C Wu, MS Sachs, RC Wek Journal of Biological Chemistry 290 (47), 28257-28271, 2015 | 96 | 2015 |
Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity JJ Sutherland, YW Webster, JA Willy, GH Searfoss, KM Goldstein, ... The pharmacogenomics journal 18 (3), 377-390, 2018 | 86 | 2018 |
Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential JJ Kwon, JA Willy, KA Quirin, RC Wek, M Korc, XM Yin, J Kota Oncotarget 7 (44), 71635, 2016 | 70 | 2016 |
Function of inhibitor of Bruton's tyrosine kinase isoform α (IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response JA Willy, SK Young, AL Mosley, S Gawrieh, JL Stevens, HC Masuoka, ... Journal of Biological Chemistry 292 (34), 14050-14065, 2017 | 22 | 2017 |
FcγRIIIa-dependent IFN-γ release in whole blood assay is predictive of therapeutic IgG1 antibodies safety NS Alakhras, J Qiu, GV Rocha, DR Witcher, A Koester, J You, DA Schaer, ... MAbs 10 (6), 913-921, 2018 | 7 | 2018 |
The integrated stress response regulates cell health of cardiac progenitors GH Searfoss, BM Paisley, KM Goldstein, TK Baker, JA Willy Toxicological Sciences 167 (1), 202-210, 2019 | 5 | 2019 |
In Vitro L6 Irritation Assay Predicts Clinical Injection Site Reactions for Small Molecules JA Willy, NE Schulte, EL Kreklau, JL Walgren, ML Renninger, TK Baker Toxicological Sciences 151 (2), 302-311, 2016 | 5 | 2016 |
Discover Toxicology: An Early Safety Assessment Approach TK Baker, SK Engle, BW Halstead, BM Paisley, GH Searfoss, JA Willy Translating Molecules into Medicines: Cross-Functional Integration at the …, 2017 | 1 | 2017 |
ER Stress Regulates Autophagy and Protein Secretion through IBTK alpha during the Pathogenesis of Non-Alcoholic Steatohepatitis JA Willy, S Gawrieh, JL Stevens, HC Masuoka, RC Wek HEPATOLOGY 63 (1 SUPP), 796A-797A, 2016 | | 2016 |