The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 133 | 2022 |
Mutations in repeating structural motifs of tropomyosin cause gain of function in skeletal muscle myopathy patients S Marston, M Memo, A Messer, M Papadaki, K Nowak, E McNamara, ... Human molecular genetics 22 (24), 4978-4987, 2013 | 90 | 2013 |
Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca2+-sensitivity and suppress the modulation of Ca2+-sensitivity by troponin I phosphorylation AE Messer, CR Bayliss, M El-Mezgueldi, CS Redwood, DG Ward, ... Archives of biochemistry and biophysics 601, 113-120, 2016 | 64 | 2016 |
Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function M Papadaki, RJ Holewinski, SB Previs, TG Martin, MJ Stachowski, A Li, ... JCI insight 3 (20), 2018 | 61 | 2018 |
Successional stages in infant gut microbiota maturation L Beller, W Deboutte, G Falony, S Vieira-Silva, RY Tito, M Valles-Colomer, ... MBio 12 (6), e01857-21, 2021 | 52 | 2021 |
TPM3 deletions cause a hypercontractile congenital muscle stiffness phenotype S Donkervoort, M Papadaki, JM De Winter, MB Neu, J Kirschner, V Bolduc, ... Annals of neurology 78 (6), 982-994, 2015 | 49 | 2015 |
Uncoupling of myofilament Ca2+ sensitivity from troponin I phosphorylation by mutations can be reversed by epigallocatechin-3-gallate M Papadaki, PG Vikhorev, SB Marston, AE Messer Cardiovascular research 108 (1), 99-110, 2015 | 36 | 2015 |
Troponin structure: its modulation by Ca 2+ and phosphorylation studied by molecular dynamics simulations JE Zamora, M Papadaki, AE Messer, SB Marston, IR Gould Physical Chemistry Chemical Physics 18 (30), 20691-20707, 2016 | 32 | 2016 |
Estrogen but not testosterone preserves myofilament function from doxorubicin-induced cardiotoxicity by reducing oxidative modifications C Rattanasopa, JA Kirk, T Bupha-Intr, M Papadaki, PP De Tombe, ... American Journal of Physiology-Heart and Circulatory Physiology, 2019 | 21 | 2019 |
Molecular Defects in Cardiac Myofilament Ca2+-Regulation Due to Cardiomyopathy-Linked Mutations Can Be Reversed by Small Molecules Binding to Troponin A Sheehan, AE Messer, M Papadaki, A Choudhry, V Kren, D Biedermann, ... Frontiers in Physiology 9, 243, 2018 | 21 | 2018 |
Myofibril orientation as a metric for characterizing heart disease W Ma, H Gong, V Jani, KH Lee, M Landim-Vieira, M Papadaki, JR Pinto, ... Biophysical journal 121 (4), 565-574, 2022 | 17 | 2022 |
Intact myocardial preparations reveal intrinsic transmural heterogeneity in cardiac mechanics FG Pitoulis, W Hasan, M Papadaki, NG Clavere, F Perbellini, SE Harding, ... Journal of Molecular and Cellular Cardiology 141, 11-16, 2020 | 17 | 2020 |
Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains M Papadaki, T Kampaengsri, SK Barrick, SG Campbell, D von Lewinski, ... Journal of molecular and cellular cardiology 162, 1-9, 2022 | 13 | 2022 |
GSK-3β localizes to the cardiac Z-disc to maintain length dependent activation MJ Stachowski-Doll, M Papadaki, TG Martin, W Ma, HM Gong, S Shao, ... Circulation research 130 (6), 871-886, 2022 | 12 | 2022 |
The importance of intrinsically disordered segments of cardiac troponin in modulating function by phosphorylation and disease-causing mutations M Papadaki, SB Marston Frontiers in physiology 7, 217775, 2016 | 12 | 2016 |
Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function M Landim-Vieira, W Ma, T Song, H Rastegarpouyani, H Gong, ... Proceedings of the National Academy of Sciences 120 (23), e2221244120, 2023 | 7 | 2023 |
Successional stages in infant gut microbiota maturation. mBio 12, e0185721 L Beller, W Deboutte, G Falony, S Vieira-Silva, RY Tito, M Valles-Colomer, ... | 6 | 2021 |
Donor hearts in the Sydney Heart Bank: reliable control but is it ‘normal’heart? S Marston, A Jacques, C Bayliss, E Dyer, M Memo, M Papadaki, A Messer Biophysical Reviews 12, 799-803, 2020 | 3 | 2020 |
Large-scale and small-scale population genetic structure of the medically important gastropod species Bulinus truncatus (Gastropoda, Heterobranchia) T Maes, Z De Corte, C Vangestel, M Virgilio, N Smitz, ... Parasites & Vectors 15 (1), 328, 2022 | 2 | 2022 |
Structural investigation of the cardiac troponin complex by molecular dynamics A Sheehan, JE Zamora, M Papadaki, A Messer, S Marston, I Gould Cardiovascular Research 111, S32-S32, 2016 | 2 | 2016 |