| Selective inhibition of tumor oncogenes by disruption of super-enhancers J Lovén, HA Hoke, CY Lin, A Lau, DA Orlando, CR Vakoc, JE Bradner, ... Cell 153 (2), 320-334, 2013 | 2833 | 2013 |
| Transcriptional amplification in tumor cells with elevated c-Myc CY Lin, J Lovén, PB Rahl, RM Paranal, CB Burge, JE Bradner, TI Lee, ... Cell 151 (1), 56-67, 2012 | 1645 | 2012 |
| Revisiting global gene expression analysis J Lovén, DA Orlando, AA Sigova, CY Lin, PB Rahl, CB Burge, DL Levens, ... Cell 151 (3), 476-482, 2012 | 705 | 2012 |
| Master transcription factors determine cell-type-specific responses to TGF-β signaling AC Mullen, DA Orlando, JJ Newman, J Lovén, RM Kumar, S Bilodeau, ... Cell 147 (3), 565-576, 2011 | 682 | 2011 |
| Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons Y Li, H Wang, J Muffat, AW Cheng, DA Orlando, J Lovén, S Kwok, ... Cell stem cell 13 (4), 446-458, 2013 | 343 | 2013 |
| DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1 M Lerner, M Harada, J Lovén, J Castro, Z Davis, D Oscier, M Henriksson, ... Experimental cell research 315 (17), 2941-2952, 2009 | 195 | 2009 |
| Genome-wide localization of small molecules L Anders, MG Guenther, J Qi, ZP Fan, JJ Marineau, PB Rahl, J Loven, ... Nature biotechnology 32 (1), 92-96, 2014 | 187 | 2014 |
| MYCN-regulated microRNAs repress estrogen receptor-α (ESR1) expression and neuronal differentiation in human neuroblastoma J Lovén, N Zinin, T Wahlström, I Müller, P Brodin, E Fredlund, U Ribacke, ... Proceedings of the National Academy of Sciences 107 (4), 1553-1558, 2010 | 159 | 2010 |
| Superenhancer analysis defines novel epigenomic subtypes of non-APL AML, including an RARα dependency targetable by SY-1425, a potent and selective RARα agonist MR McKeown, MR Corces, ML Eaton, C Fiore, E Lee, JT Lopez, ... Cancer discovery 7 (10), 1136-1153, 2017 | 138 | 2017 |
| MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma E Sonkoly, J Lovén, N Xu, F Meisgen, T Wei, P Brodin, V Jaks, M Kasper, ... Oncogenesis 1 (3), e3-e3, 2012 | 119 | 2012 |
| Targeting MYC-regulated miRNAs to combat cancer A Frenzel, J Lovén, MA Henriksson Genes & cancer 1 (6), 660-667, 2010 | 64 | 2010 |
| c‐Myc‐dependent etoposide‐induced apoptosis involves activation of Bax and caspases, and PKCdelta signaling A Albihn, J Lovén, J Ohlsson, LM Osorio, M Henriksson Journal of cellular biochemistry 98 (6), 1597-1614, 2006 | 48 | 2006 |
| MicroRNA-203 inversely correlates with differentiation grade, targets c-MYC, and functions as a tumor suppressor in cSCC W Lohcharoenkal, M Harada, J Lovén, F Meisgen, NX Landén, L Zhang, ... Journal of Investigative Dermatology 136 (12), 2485-2494, 2016 | 46 | 2016 |
| Regulation of nuclear hormone receptors by MYCN-driven miRNAs impacts neural differentiation and survival in neuroblastoma patients D Ribeiro, MDR Klarqvist, UK Westermark, G Oliynyk, J Dzieran, A Kock, ... Cell reports 16 (4), 979-993, 2016 | 31 | 2016 |
| Genome-wide determination of drug localization L Anders, MG Guenther, J Qi, ZP Fan, JJ Marineau, PB Rahl, J Lovén, ... Nature biotechnology 32 (1), 92, 2014 | 15 | 2014 |
| DeKoter, and Richard A AC Mullen, DA Orlando, JJ Newman, J Lovén, RM Kumar, S Bilodeau, ... Young, 565-76, 2011 | 13 | 2011 |
| Super-enhancers and methods of use thereof RA Young, W Whyte, D Hnisz, J Loven, H Hoke, D Orlando, CY Lin, T Lee US Patent 9,181,580, 2015 | 8 | 2015 |
| Super-enhancers and methods of use thereof RA Young, W Whyte, D Hnisz, J Loven, H Hoke, D Orlando, CY Lin, T Lee US Patent App. 14/063,337, 2014 | 6 | 2014 |
| Discovery and characterization of super-enhancer-associated dependencies in acute myeloid leukemia MR Corces-Zimmerman, M Eaton, J Lopez, N Ke, C Fritz, E Olson, ... Blood, The Journal of the American Society of Hematology 124 (21), 3539-3539, 2014 | 3 | 2014 |
| MiR-203 suppresses cutaneous squamous cell carcinoma growth and targets the myc oncogene W Lohcharoenkal, M Harada, J Lovén, F Meisgen, NX Landén, L Zhang, ... Cancer Research 76 (14_Supplement), 1098-1098, 2016 | 1 | 2016 |
