The SARS-CoV-2 vaccine pipeline: an overview WH Chen, U Strych, PJ Hotez, ME Bottazzi Current tropical medicine reports 7 (2), 61-64, 2020 | 653 | 2020 |
Recombinant protein vaccines, a proven approach against coronavirus pandemics J Pollet, WH Chen, U Strych Advanced drug delivery reviews 170, 71-82, 2021 | 236 | 2021 |
Potential for developing a SARS-CoV receptor-binding domain (RBD) recombinant protein as a heterologous human vaccine against coronavirus infectious disease (COVID)-19 WH Chen, PJ Hotez, ME Bottazzi Human vaccines & immunotherapeutics 16 (6), 1239-1242, 2020 | 157 | 2020 |
Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate WH Chen, L Du, SM Chag, C Ma, N Tricoche, X Tao, CA Seid, ... Human vaccines & immunotherapeutics 10 (3), 648-658, 2014 | 132 | 2014 |
Optimization of the production process and characterization of the yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1), a SARS vaccine candidate WH Chen, SM Chag, MV Poongavanam, AB Biter, EA Ewere, W Rezende, ... Journal of pharmaceutical sciences 106 (8), 1961-1970, 2017 | 115 | 2017 |
Yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1) formulated with alum induces protective immunity and reduces immune enhancement WH Chen, X Tao, A Agrawal, A Algaissi, BH Peng, J Pollet, U Strych, ... Vaccine, 2020 | 107* | 2020 |
Unified superresolution experiments and stochastic theory provide mechanistic insight into protein ion-exchange adsorptive separations L Kisley, J Chen, AP Mansur, B Shuang, K Kourentzi, MV Poongavanam, ... Proceedings of the National Academy of Sciences 111 (6), 2075-2080, 2014 | 97 | 2014 |
SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice J Pollet, WH Chen, L Versteeg, B Keegan, B Zhan, J Wei, Z Liu, J Lee, ... Human vaccines & immunotherapeutics 17 (8), 2356-2366, 2021 | 94 | 2021 |
A yeast-expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates M Pino, T Abid, S Pereira Ribeiro, VV Edara, K Floyd, JC Smith, MB Latif, ... Science immunology 6 (61), eabh3634, 2021 | 70 | 2021 |
A method to probe protein structure from UV absorbance spectra AB Biter, J Pollet, WH Chen, U Strych, PJ Hotez, ME Bottazzi Analytical biochemistry 587, 113450, 2019 | 59 | 2019 |
Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate WH Chen, J Wei, RT Kundu, R Adhikari, Z Liu, J Lee, L Versteeg, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (6), 129893, 2021 | 55 | 2021 |
Process development and scale-up optimization of the SARS-CoV-2 receptor binding domain–based vaccine candidate, RBD219-N1C1 J Lee, Z Liu, WH Chen, J Wei, R Kundu, R Adhikari, JA Rivera, ... Applied microbiology and biotechnology 105, 4153-4165, 2021 | 46 | 2021 |
Functionalized viral nanoparticles as ultrasensitive reporters in lateral-flow assays M Adhikari, S Dhamane, AEV Hagström, G Garvey, WH Chen, K Kourentzi, ... Analyst 138 (19), 5584-5587, 2013 | 45 | 2013 |
Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate WH Chen, J Pollet, U Strych, J Lee, Z Liu, RT Kundu, L Versteeg, MJ Villar, ... Protein Expression and Purification 190, 106003, 2022 | 35 | 2022 |
Fluorescence correlation spectroscopy study of protein transport and dynamic interactions with clustered‐charge peptide adsorbents CR Daniels, L Kisley, H Kim, WH Chen, MV Poongavanam, C Reznik, ... Journal of Molecular Recognition 25 (8), 435-442, 2012 | 29 | 2012 |
Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern J Pollet, U Strych, WH Chen, L Versteeg, B Keegan, B Zhan, J Wei, Z Liu, ... Vaccine 40 (26), 3655-3663, 2022 | 28 | 2022 |
Characterization and stability of Trypanosoma cruzi 24-C4 (Tc24-C4), a candidate antigen for a therapeutic vaccine against Chagas disease AB Biter, S Weltje, EM Hudspeth, CA Seid, CP McAtee, WH Chen, ... Journal of pharmaceutical sciences 107 (5), 1468-1473, 2018 | 26 | 2018 |
Permeability of anti-fouling PEGylated surfaces probed by fluorescence correlation spectroscopy CR Daniels, C Reznik, R Kilmer, MJ Felipe, MCR Tria, K Kourentzi, ... Colloids and Surfaces B: Biointerfaces 88 (1), 31-38, 2011 | 26 | 2011 |
Nucleic acid affinity of clustered-charge anion exchange adsorbents: Effects of ionic strength and ligand density W Chen, JY Fu, K Kourentzi, RC Willson Journal of Chromatography A 1218 (2), 258-262, 2011 | 24 | 2011 |
The factor H-binding site of CspZ as a protective target against multistrain, tick-transmitted Lyme disease AL Marcinkiewicz, I Lieknina, X Yang, PL Lederman, TM Hart, J Yates, ... Infection and immunity 88 (5), 10.1128/iai. 00956-19, 2020 | 21 | 2020 |