The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance C Lee, J Zeng, BG Drew, T Sallam, A Martin-Montalvo, J Wan, SJ Kim, ... Cell metabolism 21 (3), 443-454, 2015 | 640 | 2015 |
Mitochondrially derived peptides as novel regulators of metabolism SJ Kim, J Xiao, J Wan, P Cohen, K Yen The Journal of physiology 595 (21), 6613-6621, 2017 | 174 | 2017 |
Mitochondrial peptides modulate mitochondrial function during cellular senescence SJ Kim, HH Mehta, J Wan, C Kuehnemann, J Chen, JF Hu, AR Hoffman, ... Aging (Albany NY) 10 (6), 1239, 2018 | 129 | 2018 |
Mitochondrial-derived peptides in energy metabolism TL Merry, A Chan, JST Woodhead, JC Reynolds, H Kumagai, SJ Kim, ... American Journal of Physiology-Endocrinology and Metabolism 319 (4), E659-E666, 2020 | 103 | 2020 |
The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus SJ Kim, N Guerrero, G Wassef, J Xiao, HH Mehta, P Cohen, K Yen Oncotarget 7 (30), 46899, 2016 | 99 | 2016 |
Effects of air pollution on mitochondrial function, mitochondrial DNA methylation, and mitochondrial peptide expression CV Breton, AY Song, J Xiao, SJ Kim, HH Mehta, J Wan, K Yen, C Sioutas, ... Mitochondrion 46, 22-29, 2019 | 98 | 2019 |
Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death SJ Kim, YJ Park, IY Hwang, MBH Youdim, KS Park, YJ Oh Free Radical Biology and Medicine 53 (4), 936-950, 2012 | 94 | 2012 |
The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan K Yen, HH Mehta, SJ Kim, YH Lue, J Hoang, N Guerrero, J Port, Q Bi, ... Aging (Albany NY) 12 (12), 11185, 2020 | 90 | 2020 |
Humanin prevents age-related cognitive decline in mice and is associated with improved cognitive age in humans K Yen, J Wan, HH Mehta, B Miller, A Christensen, ME Levine, ... Scientific reports 8 (1), 14212, 2018 | 88 | 2018 |
Nuclear-encoded lncRNA MALAT1 epigenetically controls metabolic reprogramming in HCC cells through the mitophagy pathway Y Zhao, L Zhou, H Li, T Sun, X Wen, X Li, Y Meng, Y Li, M Liu, S Liu, ... Molecular Therapy-Nucleic Acids 23, 264-276, 2021 | 83 | 2021 |
Host mitochondrial transcriptome response to SARS-CoV-2 in multiple cell models and clinical samples B Miller, A Silverstein, M Flores, K Cao, H Kumagai, HH Mehta, K Yen, ... Scientific Reports 11 (1), 3, 2021 | 73 | 2021 |
Peptides derived from small mitochondrial open reading frames: Genomic, biological, and therapeutic implications B Miller, SJ Kim, H Kumagai, HH Mehta, W Xiang, J Liu, K Yen, P Cohen Experimental cell research 393 (2), 112056, 2020 | 66 | 2020 |
The mitochondrial‐derived peptide MOTS‐c is a regulator of plasma metabolites and enhances insulin sensitivity SJ Kim, B Miller, HH Mehta, J Xiao, J Wan, TE Arpawong, K Yen, P Cohen Physiological reports 7 (13), e14171, 2019 | 56 | 2019 |
Mitochondrial DNA hypomethylation is a biomarker associated with induced senescence in human fetal heart mesenchymal stem cells D Yu, Z Du, L Pian, T Li, X Wen, W Li, SJ Kim, J Xiao, P Cohen, J Cui, ... Stem cells international 2017 (1), 1764549, 2017 | 51 | 2017 |
Humanin: functional interfaces with IGF-I J Xiao, SJ Kim, P Cohen, K Yen Growth hormone & IGF research 29, 21-27, 2016 | 51 | 2016 |
Mitochondrial-derived peptides in aging and age-related diseases SJ Kim, B Miller, H Kumagai, AR Silverstein, M Flores, K Yen Geroscience 43, 1113-1121, 2021 | 49 | 2021 |
MOTS-c reduces myostatin and muscle atrophy signaling H Kumagai, AR Coelho, J Wan, HH Mehta, K Yen, A Huang, H Zempo, ... American Journal of Physiology-Endocrinology and Metabolism 320 (4), E680-E690, 2021 | 44 | 2021 |
A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c H Zempo, SJ Kim, N Fuku, Y Nishida, Y Higaki, J Wan, K Yen, B Miller, ... Aging (Albany NY) 13 (2), 1692, 2021 | 43 | 2021 |
Metabolomic profile of diet-induced obesity mice in response to humanin and small humanin-like peptide 2 treatment HH Mehta, J Xiao, R Ramirez, B Miller, SJ Kim, P Cohen, K Yen Metabolomics 15, 1-12, 2019 | 42 | 2019 |
Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension SJ Kim, A Devgan, B Miller, SM Lee, H Kumagai, KA Wilson, G Wassef, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1866 (1), 130017, 2022 | 25 | 2022 |