Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease ND Dey, MC Bombard, BP Roland, S Davidson, M Lu, J Rossignol, ... Behavioural brain research 214 (2), 193-200, 2010 | 186 | 2010 |
Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates R Mishra, M Jayaraman, BP Roland, E Landrum, T Fullam, R Kodali, ... Journal of molecular biology 415 (5), 900-917, 2012 | 93 | 2012 |
Yeast and human P4-ATPases transport glycosphingolipids using conserved structural motifs BP Roland, T Naito, JT Best, C Arnaiz-Yépez, H Takatsu, JY Roger, ... Journal of Biological Chemistry 294 (6), 1794-1806, 2019 | 64 | 2019 |
Mechanisms of endothelial cell dysfunction in cystic fibrosis L Totani, R Plebani, A Piccoli, S Di Silvestre, P Lanuti, A Recchiuti, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (12 …, 2017 | 61 | 2017 |
A tutorial for pharmacogenomics implementation through end‐to‐end clinical decision support based on ten years of experience from PREDICT M Liu, CL Vnencak‐Jones, BP Roland, CL Gatto, JL Mathe, SL Just, ... Clinical Pharmacology & Therapeutics 109 (1), 101-115, 2021 | 45 | 2021 |
Decoding P4-ATPase substrate interactions BP Roland, TR Graham Critical reviews in biochemistry and molecular biology 51 (6), 513-527, 2016 | 40 | 2016 |
Adaptive substitutions underlying cardiac glycoside insensitivity in insects exhibit epistasis in vivo AM Taverner, L Yang, ZJ Barile, B Lin, J Peng, AP Pinharanda, AS Rao, ... Elife 8, e48224, 2019 | 39 | 2019 |
Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency BP Roland, CG Amrich, CJ Kammerer, KA Stuchul, SB Larsen, S Rode, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (1), 61-69, 2015 | 38 | 2015 |
Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity BP Roland, KA Stuchul, SB Larsen, CG Amrich, AP VanDemark, ... Journal of Cell Science 126 (14), 3151-3158, 2013 | 37 | 2013 |
Structural and genetic studies demonstrate neurologic dysfunction in triosephosphate isomerase deficiency is associated with impaired synaptic vesicle dynamics BP Roland, AM Zeccola, SB Larsen, CG Amrich, AD Talsma, KA Stuchul, ... PLoS Genetics 12 (3), e1005941, 2016 | 32 | 2016 |
Directed evolution of a sphingomyelin flippase reveals mechanism of substrate backbone discrimination by a P4-ATPase BP Roland, TR Graham Proceedings of the National Academy of Sciences 113 (31), E4460-E4466, 2016 | 26 | 2016 |
A serendipitous survey of prediction algorithms for amyloidogenicity BP Roland, R Kodali, R Mishra, R Wetzel Peptide Science 100 (6), 780-789, 2013 | 23 | 2013 |
Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo BP Roland, KR Richards, SL Hrizo, S Eicher, ZJ Barile, TC Chang, ... Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (9 …, 2019 | 18 | 2019 |
Exofacial membrane composition and lipid metabolism regulates plasma membrane P4-ATPase substrate specificity BK Jain, BP Roland, TR Graham Journal of Biological Chemistry 295 (52), 17997-18009, 2020 | 8 | 2020 |
Impact of updating pharmacogenetic results: lessons learned from the PREDICT program M Liu, SL Van Driest, CL Vnencak-Jones, LAG Saucier, BP Roland, ... Journal of Personalized Medicine 11 (11), 1051, 2021 | 6 | 2021 |
Predatory fireflies and their toxic firefly prey have evolved distinct toxin resistance strategies L Yang, F Borne, A Betz, ML Aardema, Y Zhen, J Peng, R Visconti, M Wu, ... Current Biology 33 (23), 5160-5168. e7, 2023 | 5* | 2023 |
Intrastriatal transplantation of bone marrow stem cells that are genetically engineered to overexpress brain-derived neurotrophic factor reduces behavioral deficits in the … MC Bombard, ND Dey, BP Roland, M Lu, J Matchynski, S Lowrance, ... CELL TRANSPLANTATION 17 (4), 462-462, 2008 | 3 | 2008 |
The novel neuroimmunophillin, GPI 1485, attenuates age-related cognitive deficits in rats ND Dey, MC Bombard, RA Myers, AJ Boersen, BP Roland, MI Sandstrom, ... CELL TRANSPLANTATION 16 (3), 319-320, 2007 | 3 | 2007 |
Exofacial membrane composition and lipid metabolism regulates plasma membrane P4-ATPase substrate specificity BP Roland, BK Jain, TR Graham bioRxiv, 2020.06. 24.169672, 2020 | 2 | 2020 |
A Tutorial for Pharmacogenomics Implementation Through End-to-End Clinical Decision Support Based on Ten Years of Experience From PREDICT (vol 109, pg 101, 2021) M Liu, CL Vnencak-Jones, BP Roland, CL Gatto, JL Mathe, SL Just, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 112 (5), 1130-1130, 2022 | | 2022 |