| Structure of the human κ-opioid receptor in complex with JDTic H Wu, D Wacker, M Mileni, V Katritch, GW Han, E Vardy, W Liu, ... Nature 485 (7398), 327-332, 2012 | 1081 | 2012 |
| Structural features for functional selectivity at serotonin receptors D Wacker, C Wang, V Katritch, GW Han, XP Huang, E Vardy, JD McCorvy, ... Science 340 (6132), 615-619, 2013 | 801 | 2013 |
| Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography U Weierstall, D James, C Wang, TA White, D Wang, W Liu, JCH Spence, ... Nature communications 5 (1), 3309, 2014 | 613 | 2014 |
| Structural basis for molecular recognition at serotonin receptors C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ... Science 340 (6132), 610-614, 2013 | 603 | 2013 |
| How ligands illuminate GPCR molecular pharmacology D Wacker, RC Stevens, BL Roth Cell 170 (3), 414-427, 2017 | 550 | 2017 |
| Serial femtosecond crystallography of G protein–coupled receptors W Liu, D Wacker, C Gati, GW Han, D James, D Wang, G Nelson, ... Science 342 (6165), 1521-1524, 2013 | 520 | 2013 |
| Crystal structure of an LSD-bound human serotonin receptor D Wacker, S Wang, JD McCorvy, RM Betz, AJ Venkatakrishnan, A Levit, ... Cell 168 (3), 377-389. e12, 2017 | 469 | 2017 |
| Structure of the human glucagon class B G-protein-coupled receptor FY Siu, M He, C De Graaf, GW Han, D Yang, Z Zhang, C Zhou, Q Xu, ... Nature 499 (7459), 444-449, 2013 | 456 | 2013 |
| Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone S Wang, T Che, A Levit, BK Shoichet, D Wacker, BL Roth Nature 555 (7695), 269-273, 2018 | 439 | 2018 |
| Conserved Binding Mode of Human β2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography D Wacker, G Fenalti, MA Brown, V Katritch, R Abagyan, V Cherezov, ... Journal of the American Chemical Society 132 (33), 11443-11445, 2010 | 425 | 2010 |
| Structure of the nanobody-stabilized active state of the kappa opioid receptor T Che, S Majumdar, SA Zaidi, P Ondachi, JD McCorvy, S Wang, ... Cell 172 (1), 55-67. e15, 2018 | 367 | 2018 |
| Structure of a hallucinogen-activated Gq-coupled 5-HT2A serotonin receptor K Kim, T Che, O Panova, JF DiBerto, J Lyu, BE Krumm, D Wacker, ... Cell 182 (6), 1574-1588. e19, 2020 | 350 | 2020 |
| 5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology Y Peng, JD McCorvy, K Harpsøe, K Lansu, S Yuan, P Popov, L Qu, M Pu, ... Cell 172 (4), 719-730. e14, 2018 | 232 | 2018 |
| D4 dopamine receptor high-resolution structures enable the discovery of selective agonists S Wang, D Wacker, A Levit, T Che, RM Betz, JD McCorvy, ... Science 358 (6361), 381-386, 2017 | 227 | 2017 |
| Artificial intelligence and machine learning‐aided drug discovery in central nervous system diseases: State‐of‐the‐arts and future directions S Vatansever, A Schlessinger, D Wacker, HÜ Kaniskan, J Jin, MM Zhou, ... Medicinal research reviews 41 (3), 1427-1473, 2021 | 196 | 2021 |
| Structural determinants of 5-HT2B receptor activation and biased agonism JD McCorvy, D Wacker, S Wang, B Agegnehu, J Liu, K Lansu, AR Tribo, ... Nature structural & molecular biology 25 (9), 787-796, 2018 | 144 | 2018 |
| GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles AA Thompson, JJ Liu, E Chun, D Wacker, H Wu, V Cherezov, RC Stevens Methods 55 (4), 310-317, 2011 | 107 | 2011 |
| Nanobody-enabled monitoring of kappa opioid receptor states T Che, J English, BE Krumm, K Kim, E Pardon, RHJ Olsen, S Wang, ... Nature communications 11 (1), 1145, 2020 | 105 | 2020 |
| VEGAS as a platform for facile directed evolution in mammalian cells JG English, RHJ Olsen, K Lansu, M Patel, K White, AS Cockrell, D Singh, ... Cell 178 (3), 748-761. e17, 2019 | 94 | 2019 |
| Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity DM Ferrero, D Wacker, MA Roque, MW Baldwin, RC Stevens, SD Liberles ACS chemical biology 7 (7), 1184-1189, 2012 | 90 | 2012 |
