| Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR–Cas9 system R Torres, MC Martin, A Garcia, JC Cigudosa, JC Ramirez, ... Nature communications 5 (1), 3964, 2014 | 290 | 2014 |
| Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres S Espejel, S Franco, S Rodríguez‐Perales, SD Bouffler, JC Cigudosa, ... The EMBO journal, 2002 | 257 | 2002 |
| Immunohistochemical characteristics defined by tissue microarray of hereditary breast cancer not attributable to BRCA1 or BRCA2 mutations: differences from breast carcinomas … J Palacios, E Honrado, A Osorio, A Cazorla, D Sarrió, A Barroso, ... Clinical Cancer Research 9 (10), 3606-3614, 2003 | 238 | 2003 |
| Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers J Palacios, E Honrado, A Osorio, A Cazorla, D Sarrió, A Barroso, ... Breast cancer research and treatment 90, 5-14, 2005 | 214 | 2005 |
| Differential Gene Expression Profile in Endometrioid and Nonendometrioid Endometrial Carcinoma: STK15 Is Frequently Overexpressed and … G Moreno-Bueno, C Sánchez-Estévez, R Cassia, S Rodríguez-Perales, ... Cancer research 63 (18), 5697-5702, 2003 | 198 | 2003 |
| Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases MF Paz, S Wei, JC Cigudosa, S Rodriguez-Perales, MA Peinado, ... Human molecular genetics 12 (17), 2209-2219, 2003 | 166 | 2003 |
| A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li–Fraumeni-like families O Calvete, P Martinez, P Garcia-Pavia, C Benitez-Buelga, ... Nature communications 6 (1), 8383, 2015 | 165 | 2015 |
| Cyclin D1 gene (CCND1) mutations in endometrial cancer G Moreno-Bueno, S Rodríguez-Perales, C Sanchez-Estevez, ... Oncogene 22 (38), 6115-6118, 2003 | 154 | 2003 |
| A faecal microbiota signature with high specificity for pancreatic cancer E Kartal, TSB Schmidt, E Molina-Montes, S Rodríguez-Perales, J Wirbel, ... Gut 71 (7), 1359-1372, 2022 | 153 | 2022 |
| MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas B Oldrini, N Vaquero-Siguero, Q Mu, P Kroon, Y Zhang, M Galán-Ganga, ... Nature communications 11 (1), 3883, 2020 | 138 | 2020 |
| Immune profiling and quantitative analysis decipher the clinical role of immune-checkpoint expression in the tumor immune microenvironment of DLBCL ZY Xu-Monette, M Xiao, Q Au, R Padmanabhan, B Xu, N Hoe, ... Cancer immunology research 7 (4), 644-657, 2019 | 136 | 2019 |
| CRISPR/Cas9 for cancer therapy: hopes and challenges M Martinez-Lage, P Puig-Serra, P Menendez, R Torres-Ruiz, ... Biomedicines 6 (4), 105, 2018 | 134 | 2018 |
| DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia S Alvarez, J Suela, A Valencia, A Fernández, M Wunderlich, X Agirre, ... PloS one 5 (8), e12197, 2010 | 111 | 2010 |
| Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism S García-Silva, A Benito-Martín, L Nogués, A Hernández-Barranco, ... Nature Cancer 2 (12), 1387-1405, 2021 | 103 | 2021 |
| Distinctive gene expression of human lung adenocarcinomas carrying LKB1 mutations P Fernandez, J Carretero, PP Medina, AI Jimenez, S Rodriguez-Perales, ... Oncogene 23 (29), 5084-5091, 2004 | 103 | 2004 |
| Clinically relevant correction of recessive dystrophic epidermolysis bullosa by dual sgRNA CRISPR/Cas9-mediated gene editing J Bonafont, Á Mencía, M García, R Torres, S Rodríguez, M Carretero, ... Molecular Therapy 27 (5), 986-998, 2019 | 101 | 2019 |
| Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma R Cassia, G Moreno‐Bueno, S Rodríguez‐Perales, D Hardisson, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2003 | 97 | 2003 |
| In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells M Martinez-Lage, R Torres-Ruiz, P Puig-Serra, P Moreno-Gaona, ... Nature communications 11 (1), 5060, 2020 | 93 | 2020 |
| Gain-of-function mutations in DNMT3A in patients with paraganglioma L Remacha, M Currás-Freixes, R Torres-Ruiz, F Schiavi, R Torres-Pérez, ... Genetics in Medicine 20 (12), 1644-1651, 2018 | 91 | 2018 |
| CRISPR-Cas9 technology: applications and human disease modelling Guest Editors: Lu Xiao-Jie and Ji Li-Juan, R Torres-Ruiz, ... Briefings in Functional Genomics 16 (1), 4-12, 2017 | 79 | 2017 |
Raul Torres RuizStaff Scientist, CNIO // Junior PI, CIEMAT在 cnio.es 的电子邮件经过验证
