关注
Viktor T. Lemgart, PhD
Viktor T. Lemgart, PhD
Senior Scientist, Sanofi
在 sanofi.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Identification of preexisting adaptive immunity to Cas9 proteins in humans
CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart, ...
Nature medicine 25 (2), 249-254, 2019
9482019
Highly efficient and marker-free genome editing of human pluripotent stem cells by CRISPR-Cas9 RNP and AAV6 donor-mediated homologous recombination
RM Martin, K Ikeda, MK Cromer, N Uchida, T Nishimura, R Romano, ...
Cell stem cell 24 (5), 821-828. e5, 2019
1652019
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells
MK Cromer, J Camarena, RM Martin, BJ Lesch, CA Vakulskas, NM Bode, ...
Nature medicine 27 (4), 677-687, 2021
652021
SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells
Y Hara, VT Lemgart, N Halland, K Mahdaviani, JA Ribeil, S Lessard, ...
Blood Advances 7 (11), 2317-2323, 2023
12023
LIPID NANOPARTICLES AND IONIZABLE CATIONIC LIPIDS, AND METHODS OF SYNTHESIS AND USE THEREOF
M Ali, AW Boesch, DC Drummond, W Kuhlman, V Lemgart, U Nielsen
WO Patent WO/2023/240,156, 2023
2023
Genomic discovery and functional validation of MRP1 as a novel fetal hemoglobin modulator and potential therapeutic target in sickle cell disease
Y Hara, E Kawabata, VT Lemgart, PG Bronson, A Hicks, R Peters, ...
medRxiv, 2023.03. 14.23287244, 2023
2023
Reprogramming Immune Cells in situ: A Targeted LNP Delivery Technology Utilizing IVT mRNA
VT Lemgart
DTU Health Technology, 2023
2023
Inhibition of MRP1 Induces Fetal Hemoglobin through NRF2 Activation to Protect Human Erythroid Cells from Sickling
Y Hara, E Kawabata, VT Lemgart, PG Bronson, A Hicks, ...
Blood 140 (Supplement 1), 952-953, 2022
2022
Targeting beta-Globin Gene into alpha-Globin Locus in Human Hematopoietic Stem and Progenitor Cells
MK Cromer, J Camarena, RM Martin, BJ Lesch, VT Lemgart, RO Bak, ...
MOLECULAR THERAPY 27 (4), 400-400, 2019
2019
2019 Identification of preexisting adaptive immunity to Cas9 proteins in humans
CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart
Nat. Med 25, 249, 0
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