Identification of preexisting adaptive immunity to Cas9 proteins in humans CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart, ... Nature medicine 25 (2), 249-254, 2019 | 948 | 2019 |
Highly efficient and marker-free genome editing of human pluripotent stem cells by CRISPR-Cas9 RNP and AAV6 donor-mediated homologous recombination RM Martin, K Ikeda, MK Cromer, N Uchida, T Nishimura, R Romano, ... Cell stem cell 24 (5), 821-828. e5, 2019 | 165 | 2019 |
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells MK Cromer, J Camarena, RM Martin, BJ Lesch, CA Vakulskas, NM Bode, ... Nature medicine 27 (4), 677-687, 2021 | 65 | 2021 |
SGK1 inhibition induces fetal hemoglobin expression and delays polymerization in sickle erythroid cells Y Hara, VT Lemgart, N Halland, K Mahdaviani, JA Ribeil, S Lessard, ... Blood Advances 7 (11), 2317-2323, 2023 | 1 | 2023 |
LIPID NANOPARTICLES AND IONIZABLE CATIONIC LIPIDS, AND METHODS OF SYNTHESIS AND USE THEREOF M Ali, AW Boesch, DC Drummond, W Kuhlman, V Lemgart, U Nielsen WO Patent WO/2023/240,156, 2023 | | 2023 |
Genomic discovery and functional validation of MRP1 as a novel fetal hemoglobin modulator and potential therapeutic target in sickle cell disease Y Hara, E Kawabata, VT Lemgart, PG Bronson, A Hicks, R Peters, ... medRxiv, 2023.03. 14.23287244, 2023 | | 2023 |
Reprogramming Immune Cells in situ: A Targeted LNP Delivery Technology Utilizing IVT mRNA VT Lemgart DTU Health Technology, 2023 | | 2023 |
Inhibition of MRP1 Induces Fetal Hemoglobin through NRF2 Activation to Protect Human Erythroid Cells from Sickling Y Hara, E Kawabata, VT Lemgart, PG Bronson, A Hicks, ... Blood 140 (Supplement 1), 952-953, 2022 | | 2022 |
Targeting beta-Globin Gene into alpha-Globin Locus in Human Hematopoietic Stem and Progenitor Cells MK Cromer, J Camarena, RM Martin, BJ Lesch, VT Lemgart, RO Bak, ... MOLECULAR THERAPY 27 (4), 400-400, 2019 | | 2019 |
2019 Identification of preexisting adaptive immunity to Cas9 proteins in humans CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart Nat. Med 25, 249, 0 | | |