Mechanism of human SIRT1 activation by resveratrol MT Borra, BC Smith, JM Denu Journal of Biological Chemistry 280 (17), 17187-17195, 2005 | 1328 | 2005 |
Chemical mechanisms of histone lysine and arginine modifications BC Smith, JM Denu Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1789 (1), 45-57, 2009 | 484 | 2009 |
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction WC Hallows, W Yu, BC Smith, MK Devires, JJ Ellinger, S Someya, ... Molecular cell 41 (2), 139-149, 2011 | 440 | 2011 |
Mechanisms of S-nitrosothiol formation and selectivity in nitric oxide signaling BC Smith, MA Marletta Current opinion in chemical biology 16 (5-6), 498-506, 2012 | 277 | 2012 |
Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation MT Schmidt, BC Smith, MD Jackson, JM Denu Journal of Biological Chemistry 279 (38), 40122-40129, 2004 | 191 | 2004 |
Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide BC Smith, JM Denu Biochemistry 46 (50), 14478-14486, 2007 | 170 | 2007 |
Mechanisms and molecular probes of sirtuins BC Smith, WC Hallows, JM Denu Chemistry & biology 15 (10), 1002-1013, 2008 | 169 | 2008 |
Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases BC Smith, JM Denu Journal of Biological Chemistry 282 (51), 37256-37265, 2007 | 163 | 2007 |
A continuous microplate assay for sirtuins and nicotinamide-producing enzymes BC Smith, WC Hallows, JM Denu Analytical biochemistry 394 (1), 101-109, 2009 | 162 | 2009 |
Small molecule regulation of Sir2 protein deacetylases O Grubisha, BC Smith, JM Denu The FEBS journal 272 (18), 4607-4616, 2005 | 161 | 2005 |
Mitochondrial metabolic reprogramming by CD36 signaling drives macrophage inflammatory responses Y Chen, M Yang, W Huang, W Chen, Y Zhao, ML Schulte, P Volberding, ... Circulation research 125 (12), 1087-1102, 2019 | 149 | 2019 |
Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine BC Smith, JM Denu Biochemistry 45 (1), 272-282, 2006 | 137 | 2006 |
Molecular architecture of mammalian nitric oxide synthases MG Campbell, BC Smith, CS Potter, B Carragher, MA Marletta Proceedings of the National Academy of Sciences 111 (35), E3614-E3623, 2014 | 122 | 2014 |
Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation BC Smith, ES Underbakke, DW Kulp, WR Schief, MA Marletta Proceedings of the National Academy of Sciences 110 (38), E3577-E3586, 2013 | 104 | 2013 |
Sir2 Deacetylases Exhibit Nucleophilic Participation of Acetyl-Lysine in NAD+ Cleavage BC Smith, JM Denu Journal of the American Chemical Society 129 (18), 5802-5803, 2007 | 101 | 2007 |
SIRT3 substrate specificity determined by peptide arrays and machine learning BC Smith, B Settles, WC Hallows, MW Craven, JM Denu ACS chemical biology 6 (2), 146-157, 2011 | 87 | 2011 |
Linking SIRT2 to Parkinson’s disease AL Garske, BC Smith, JM Denu ACS Chemical Biology 2 (8), 529-532, 2007 | 77 | 2007 |
Nitrosothiol formation and S-nitrosation signaling through nitric oxide synthases SL Wynia-Smith, BC Smith Nitric Oxide 63, 52-60, 2017 | 67 | 2017 |
Nitric oxide antagonism to glioblastoma photodynamic therapy and mitigation thereof by BET bromodomain inhibitor JQ1 JM Fahey, JS Stancill, BC Smith, AW Girotti Journal of Biological Chemistry 293 (14), 5345-5359, 2018 | 54 | 2018 |
Hydrolysis of O-acetyl-ADP-ribose isomers by ADP-ribosylhydrolase 3 A Kasamatsu, M Nakao, BC Smith, LR Comstock, T Ono, J Kato, JM Denu, ... Journal of Biological Chemistry 286 (24), 21110-21117, 2011 | 52 | 2011 |