Expression of PD-L1 on canine tumor cells and enhancement of IFN-γ production from tumor-infiltrating cells by PD-L1 blockade N Maekawa, S Konnai, R Ikebuchi, T Okagawa, M Adachi, S Takagi, ... PloS one 9 (6), e98415, 2014 | 145 | 2014 |
A canine chimeric monoclonal antibody targeting PD-L1 and its clinical efficacy in canine oral malignant melanoma or undifferentiated sarcoma N Maekawa, S Konnai, S Takagi, Y Kagawa, T Okagawa, A Nishimori, ... Scientific reports 7 (1), 8951, 2017 | 139 | 2017 |
Immunohistochemical analysis of PD-L1 expression in canine malignant cancers and PD-1 expression on lymphocytes in canine oral melanoma N Maekawa, S Konnai, T Okagawa, A Nishimori, R Ikebuchi, Y Izumi, ... PLoS One 11 (6), e0157176, 2016 | 122 | 2016 |
PD-L1 immunohistochemistry for canine cancers and clinical benefit of anti-PD-L1 antibody in dogs with pulmonary metastatic oral malignant melanoma N Maekawa, S Konnai, M Nishimura, Y Kagawa, S Takagi, K Hosoya, ... NPJ precision oncology 5 (1), 10, 2021 | 74 | 2021 |
Blockade of bovine PD-1 increases T cell function and inhibits bovine leukemia virus expression in B cells in vitro R Ikebuchi, S Konnai, T Okagawa, K Yokoyama, C Nakajima, Y Suzuki, ... Veterinary Research 44, 1-15, 2013 | 71 | 2013 |
Influence of PD‐L 1 cross‐linking on cell death in PD‐L 1‐expressing cell lines and bovine lymphocytes R Ikebuchi, S Konnai, T Okagawa, K Yokoyama, C Nakajima, Y Suzuki, ... Immunology 142 (4), 551-561, 2014 | 61 | 2014 |
Detection of bovine leukemia virus and identification of its genotype in Mongolian cattle N Ochirkhuu, S Konnai, R Odbileg, A Nishimori, T Okagawa, S Murata, ... Archives of virology 161, 985-991, 2016 | 53 | 2016 |
Bovine immunoinhibitory receptors contribute to suppression of Mycobacterium avium subsp. paratuberculosis-specific T-cell responses T Okagawa, S Konnai, A Nishimori, R Ikebuchi, S Mizorogi, R Nagata, ... Infection and immunity 84 (1), 77-89, 2016 | 51 | 2016 |
Cooperation of PD-1 and LAG-3 contributes to T-cell exhaustion in Anaplasma marginale-infected cattle T Okagawa, S Konnai, JR Deringer, MW Ueti, GA Scoles, S Murata, ... Infection and immunity 84 (10), 2779-2790, 2016 | 49 | 2016 |
Prostaglandin E2–induced immune exhaustion and enhancement of antiviral effects by anti–PD-L1 antibody combined with COX-2 inhibitor in bovine leukemia virus infection Y Sajiki, S Konnai, T Okagawa, A Nishimori, N Maekawa, S Goto, K Watari, ... The Journal of Immunology 203 (5), 1313-1324, 2019 | 47 | 2019 |
Intrauterine infection with bovine leukemia virus in pregnant dam with high viral load Y Sajiki, S Konnai, A Nishimori, T Okagawa, N Maekawa, S Goto, ... Journal of Veterinary Medical Science 79 (12), 2036-2039, 2017 | 46 | 2017 |
Bovine leukemia virus reduces anti‐viral cytokine activities and NK cytotoxicity by inducing TGF‐β secretion from regulatory T cells K Ohira, A Nakahara, S Konnai, T Okagawa, A Nishimori, N Maekawa, ... Immunity, Inflammation and Disease 4 (1), 52-63, 2016 | 46 | 2016 |
Increase of cells expressing PD‐1 and PD‐L1 and enhancement of IFN‐γ production via PD‐1/PD‐L1 blockade in Bovine mycoplasmosis S Goto, S Konnai, T Okagawa, A Nishimori, N Maekawa, S Gondaira, ... Immunity, inflammation and disease 5 (3), 355-363, 2017 | 42 | 2017 |
In vitro and in vivo antivirus activity of an anti-programmed death-ligand 1 (PD-L1) rat-bovine chimeric antibody against bovine leukemia virus infection A Nishimori, S Konnai, T Okagawa, N Maekawa, R Ikebuchi, S Goto, ... PLoS One 12 (4), e0174916, 2017 | 42 | 2017 |
Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection T Okagawa, S Konnai, R Ikebuchi, S Suzuki, T Shirai, Y Sunden, ... Veterinary research 43, 1-14, 2012 | 41 | 2012 |
Increased expression of the regulatory T cell-associated marker CTLA-4 in bovine leukemia virus infection S Suzuki, S Konnai, T Okagawa, R Ikebuchi, A Nishimori, J Kohara, ... Veterinary Immunology and Immunopathology 163 (3-4), 115-124, 2015 | 36 | 2015 |
Enhanced expression of LAG-3 on lymphocyte subpopulations from persistently lymphocytotic cattle infected with bovine leukemia virus S Konnai, S Suzuki, T Shirai, R Ikebuchi, T Okagawa, Y Sunden, ... Comparative immunology, microbiology and infectious diseases 36 (1), 63-69, 2013 | 36 | 2013 |
Identification of an atypical enzootic bovine leukosis in Japan by using a novel classification of bovine leukemia based on immunophenotypic analysis A Nishimori, S Konnai, T Okagawa, N Maekawa, S Goto, R Ikebuchi, ... Clinical and Vaccine Immunology: CVI 24 (9), 2017 | 35 | 2017 |
Molecular epidemiological survey and genetic analysis of vector-borne infections of cattle in Luzon Island, the Philippines N Ochirkhuu, S Konnai, CN Mingala, T Okagawa, M Villanueva, ... Veterinary parasitology 212 (3-4), 161-167, 2015 | 35 | 2015 |
Prostaglandin E2 Induction Suppresses the Th1 Immune Responses in Cattle with Johne's Disease Y Sajiki, S Konnai, T Okagawa, A Nishimori, N Maekawa, S Goto, ... Infection and immunity 86 (5), 10.1128/iai. 00910-17, 2018 | 34 | 2018 |