Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation JV Lee, A Carrer, S Shah, NW Snyder, S Wei, S Venneti, AJ Worth, ... Cell Metabolism 20 (2), 306-319, 2014 | 562 | 2014 |
Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice MJ Harms, J Ishibashi, W Wang, HW Lim, S Goyama, T Sato, M Kurokawa, ... Cell Metabolism 19 (4), 593-604, 2014 | 384 | 2014 |
EBF2 determines and maintains brown adipocyte identity S Rajakumari, J Wu, J Ishibashi, HW Lim, AH Giang, KJ Won, RR Reed, ... Cell Metabolism 17 (4), 562-574, 2013 | 382 | 2013 |
Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue DA Hill, HW Lim, YH Kim, WY Ho, YH Foong, VL Nelson, HCB Nguyen, ... Proceedings of the National Academy of Sciences 115 (22), E5096-E5105, 2018 | 363 | 2018 |
Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells R Xie, LJ Everett, HW Lim, NA Patel, J Schug, E Kroon, OG Kelly, A Wang, ... Cell Stem Cell 12 (2), 224-237, 2013 | 263 | 2013 |
Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor Z Sun, D Feng, B Fang, SE Mullican, SH You, HW Lim, LJ Everett, ... Molecular Cell 52 (6), 769-782, 2013 | 254 | 2013 |
Ebf2 is a selective marker of brown and beige adipogenic precursor cells W Wang, M Kissig, S Rajakumari, L Huang, H Lim, KJ Won, P Seale Proceedings of the National Academy of Sciences 111 (40), 14466-14471, 2014 | 232 | 2014 |
Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo SH You, HW Lim, Z Sun, M Broache, KJ Won, MA Lazar Nature Structural & Molecular Biology 20 (2), 182-187, 2013 | 222 | 2013 |
Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo HW Lim, NH Uhlenhaut, A Rauch, J Weiner, S Hübner, N Hübner, KJ Won, ... Genome Research 25 (6), 836-844, 2015 | 182 | 2015 |
A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate W Wang, J Ishibashi, S Trefely, M Shao, AJ Cowan, A Sakers, HW Lim, ... Cell Metabolism, 2019 | 178 | 2019 |
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge MJ Emmett, HW Lim, J Jager, HJ Richter, M Adlanmerini, LC Peed, ... Nature 546 (7659), 544-548, 2017 | 173 | 2017 |
PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program MJ Harms, HW Lim, Y Ho, SN Shapira, J Ishibashi, S Rajakumari, ... Genes & Development 29 (3), 298-307, 2015 | 144 | 2015 |
Genetic variation determines PPARγ function and anti-diabetic drug response in vivo Cell 162 (1), 33–44, 2015 | 129 | 2015 |
EBF2 promotes the recruitment of beige adipocytes in white adipose tissue RR Stine, SN Shapira, HW Lim, J Ishibashi, M Harms, KJ Won, P Seale Molecular Metabolism 5 (1), 57-65, 2016 | 111 | 2016 |
Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers SE Step, HW Lim, JM Marinis, A Prokesch, DJ Steger, SH You, KJ Won, ... Genes & Development 28 (9), 1018-1028, 2014 | 106 | 2014 |
PRDM16 maintains homeostasis of the intestinal epithelium by controlling region-specific metabolism RR Stine, AP Sakers, T TeSlaa, M Kissig, ZE Stine, CW Kwon, L Cheng, ... Cell stem cell 25 (6), 830-845. e8, 2019 | 75 | 2019 |
Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism. S Shah, WJ Carriveau, J Li, SL Campbell, PK Kopinski, HW Lim, N Daurio, ... Oncotarget 7 (28), 43713-43730, 2016 | 73 | 2016 |
EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex SN Shapira, HW Lim, S Rajakumari, AP Sakers, J Ishibashi, MJ Harms, ... Genes & development 31 (7), 660-673, 2017 | 71 | 2017 |
LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells BN Ediger, HW Lim, C Juliana, DN Groff, LQT Williams, G Dominguez, ... Journal of Clinical Investigation 127 (1), 215-229, 2017 | 71 | 2017 |
PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing M Kissig, J Ishibashi, MJ Harms, HW Lim, RR Stine, KJ Won, P Seale The EMBO journal 36 (11), 1528-1542, 2017 | 62 | 2017 |