| Geroscience: linking aging to chronic disease BK Kennedy, SL Berger, A Brunet, J Campisi, AM Cuervo, ES Epel, ... Cell 159 (4), 709-713, 2014 | 2201 | 2014 |
| Trends in oxidative aging theories FL Muller, MS Lustgarten, Y Jang, A Richardson, H Van Remmen Free Radical Biology and Medicine 43 (4), 477-503, 2007 | 1433 | 2007 |
| Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity DW Lamming, L Ye, P Katajisto, MD Goncalves, M Saitoh, DM Stevens, ... science 335 (6076), 1638-1643, 2012 | 1337 | 2012 |
| Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-β levels in a mouse model of Alzheimer's disease P Spilman, N Podlutskaya, MJ Hart, J Debnath, O Gorostiza, D Bredesen, ... PloS one 5 (4), e9979, 2010 | 1155 | 2010 |
| Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-β, and Tau: effects on cognitive impairments A Caccamo, S Majumder, A Richardson, R Strong, S Oddo Journal of Biological Chemistry 285 (17), 13107-13120, 2010 | 1004 | 2010 |
| Does oxidative damage to DNA increase with age? ML Hamilton, H Van Remmen, JA Drake, H Yang, ZM Guo, K Kewitt, ... Proceedings of the National Academy of Sciences 98 (18), 10469-10474, 2001 | 998 | 2001 |
| Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging H Van Remmen, Y Ikeno, M Hamilton, M Pahlavani, N Wolf, SR Thorpe, ... Physiological genomics 16 (1), 29-37, 2003 | 910 | 2003 |
| The role of oxidative damage and stress in aging A Bokov, A Chaudhuri, A Richardson Mechanisms of ageing and development 125 (10-11), 811-826, 2004 | 881 | 2004 |
| The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults LJ Yant, Q Ran, L Rao, H Van Remmen, T Shibatani, JG Belter, L Motta, ... Free Radical Biology and Medicine 34 (4), 496-502, 2003 | 846 | 2003 |
| Is the oxidative stress theory of aging dead? VI Pérez, A Bokov, H Van Remmen, J Mele, Q Ran, Y Ikeno, A Richardson Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (10), 1005-1014, 2009 | 738 | 2009 |
| Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice MD Williams, H Van Remmen, CC Conrad, TT Huang, CJ Epstein, ... Journal of Biological Chemistry 273 (43), 28510-28515, 1998 | 549 | 1998 |
| Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging? AB Salmon, A Richardson, VI Pérez Free Radical Biology and Medicine 48 (5), 642-655, 2010 | 532 | 2010 |
| Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat VI Pérez, R Buffenstein, V Masamsetti, S Leonard, AB Salmon, J Mele, ... Proceedings of the National Academy of Sciences 106 (9), 3059-3064, 2009 | 501 | 2009 |
| Methionine oxidation and aging ER Stadtman, H Van Remmen, A Richardson, NB Wehr, RL Levine Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1703 (2), 135-140, 2005 | 492 | 2005 |
| Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits S Majumder, A Richardson, R Strong, S Oddo PloS one 6 (9), e25416, 2011 | 460 | 2011 |
| The overexpression of major antioxidant enzymes does not extend the lifespan of mice VI Pérez, H Van Remmen, A Bokov, CJ Epstein, J Vijg, A Richardson Aging cell 8 (1), 73-75, 2009 | 419 | 2009 |
| Expression of heat shock protein 70 is altered by age and diet at the level of transcription AR Heydari, B Wu, R Takahashi, R Strong, A Richardson Molecular and cellular biology, 1993 | 410 | 1993 |
| Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production FL Muller, W Song, YC Jang, Y Liu, M Sabia, A Richardson, ... American journal of physiology-Regulatory, integrative and comparative …, 2007 | 398 | 2007 |
| Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models? JL Styskal, H Van Remmen, A Richardson, AB Salmon Free radical biology and medicine 52 (1), 46-58, 2012 | 372 | 2012 |
| Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration YC Jang, MS Lustgarten, Y Liu, FL Muller, A Bhattacharya, H Liang, ... The FASEB Journal 24 (5), 1376, 2010 | 344 | 2010 |
