Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum J Wang, CJ Zhang, WN Chia, CCY Loh, Z Li, YM Lee, Y He, LX Yuan, ... Nature communications 6, 10111, 2015 | 641 | 2015 |
What has traditional Chinese medicine delivered for modern medicine? J Wang, YK Wong, F Liao Expert Reviews in Molecular Medicine 20, e4, 2018 | 269 | 2018 |
Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action YK Wong, C Xu, KA Kalesh, Y He, Q Lin, WSF Wong, HM Shen, J Wang Medicinal research reviews 37 (6), 1492-1517, 2017 | 215 | 2017 |
Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma Z Li, H Dai, X Huang, J Feng, J Deng, Z Wang, X Yang, Y Liu, Y Wu, ... Acta Pharmacologica Sinica 42 (2), 301-310, 2021 | 194 | 2021 |
Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways J Zhang, S Ng, J Wang, J Zhou, SH Tan, N Yang, Q Lin, D Xia, HM Shen Autophagy 11 (4), 629-642, 2015 | 173 | 2015 |
Traditional Chinese medicine in COVID-19 M Lyu, G Fan, G Xiao, T Wang, D Xu, J Gao, S Ge, Q Li, Y Ma, H Zhang, ... Acta Pharmaceutica Sinica B 11 (11), 3337-3363, 2021 | 162 | 2021 |
PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy L Wang, YL Cho, Y Tang, J Wang, JE Park, Y Wu, C Wang, Y Tong, ... Cell research 28 (8), 787-802, 2018 | 152 | 2018 |
Exosomes as potential sources of biomarkers in colorectal cancer Y Xiao, J Zhong, B Zhong, J Huang, L Jiang, Y Jiang, J Yuan, J Sun, L Dai, ... Cancer letters 476, 13-22, 2020 | 149 | 2020 |
Artemisinin, the magic drug discovered from traditional Chinese medicine J Wang, C Xu, YK Wong, Y Li, F Liao, T Jiang, Y Tu Engineering 5 (1), 32-39, 2019 | 144 | 2019 |
Target identification of natural and traditional medicines with quantitative chemical proteomics approaches J Wang, L Gao, YM Lee, KA Kalesh, YS Ong, J Lim, JE Jee, H Sun, ... Pharmacology & Therapeutics 162, 10-22, 2016 | 123 | 2016 |
Target identification of natural medicine with chemical proteomics approach: probe synthesis, target fishing and protein identification X Chen, Y Wang, N Ma, J Tian, Y Shao, B Zhu, YK Wong, Z Liang, C Zou, ... Signal Transduction and Targeted Therapy 5 (1), 72, 2020 | 117 | 2020 |
2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells N Ma, J Hu, ZM Zhang, W Liu, M Huang, Y Fan, X Yin, J Wang, K Ding, ... Journal of the American Chemical Society 142 (13), 6051-6059, 2020 | 116 | 2020 |
Curcumin targets the TFEB-lysosome pathway for induction of autophagy J Zhang, J Wang, J Xu, Y Lu, J Jiang, L Wang, HM Shen, D Xia Oncotarget, 2016 | 115 | 2016 |
In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line J Wang, J Zhang, CJ Zhang, YK Wong, TK Lim, ZC Hua, B Liu, ... Scientific reports 6, 22146, 2016 | 110 | 2016 |
A quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide, a promising anticancer agent that suppresses tumor metastasis J Wang, XF Tan, P Yang, J Zhou, M Gao, Z Li, TK Lim, Y He, CS Ong, ... Molecular & Cellular Proteomics 13 (3), 876-886, 2014 | 110 | 2014 |
Extracellular vesicles in type 2 diabetes mellitus: key roles in pathogenesis, complications, and therapy Y Xiao, L Zheng, X Zou, J Wang*, J Zhong*, T Zhong* Journal of Extracellular Vesicles 8 (1), 1625677, 2019 | 109 | 2019 |
Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1 P Luo, D Liu, Q Zhang, F Yang, YK Wong, F Xia, J Zhang, J Chen, Y Tian, ... Acta Pharmaceutica Sinica B 12 (5), 2300-2314, 2022 | 103 | 2022 |
Mechanistic investigation of the specific anticancer property of artemisinin and its combination with aminolevulinic acid for enhanced anticolorectal cancer activity J Wang, J Zhang, Y Shi, C Xu, C Zhang, YK Wong, YM Lee, S Krishna, ... ACS central science 3 (7), 743-750, 2017 | 102 | 2017 |
Mechanism-Guided Design and Synthesis of a Mitochondria-Targeting Artemisinin Analogue with Enhanced Anticancer Activity BL Chong-Jing Zhang, Jigang Wang*, Jianbin Zhang, Yew Mun Lee, Guangxue Feng ... Angew. Chem. Int. Ed., 55, 13770-13774, 2016 | 100* | 2016 |
Importance of TFEB acetylation in control of its transcriptional activity and lysosomal function in response to histone deacetylase inhibitors J Zhang, J Wang, Z Zhou, JE Park, L Wang, S Wu, X Sun, L Lu, T Wang, ... Autophagy 14 (6), 1043-1059, 2018 | 95 | 2018 |