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Daniel P. Cahill
Daniel P. Cahill
Harvard - Massachusetts General Hospital
在 mgh.harvard.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
AP Patel, I Tirosh, JJ Trombetta, AK Shalek, SM Gillespie, H Wakimoto, ...
Science 344 (6190), 1396-1401, 2014
44352014
Patterns of somatic mutation in human cancer genomes
C Greenman, P Stephens, R Smith, GL Dalgliesh, C Hunter, G Bignell, ...
Nature 446 (7132), 153-158, 2007
37602007
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
TT Batchelor, AG Sorensen, E di Tomaso, WT Zhang, DG Duda, ...
Cancer cell 11 (1), 83-95, 2007
20882007
Mutations of mitotic checkpoint genes in human cancers
DP Cahill, C Lengauer, J Yu, GJ Riggins, JKV Willson, SD Markowitz, ...
Nature 392 (6673), 300-303, 1998
19461998
An integrative model of cellular states, plasticity, and genetics for glioblastoma
C Neftel, J Laffy, MG Filbin, T Hara, ME Shore, GJ Rahme, AR Richman, ...
Cell 178 (4), 835-849. e21, 2019
17612019
Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma
KPL Bhat, V Balasubramaniyan, B Vaillant, R Ezhilarasan, K Hummelink, ...
Cancer cell 24 (3), 331-346, 2013
11032013
Genetic instability and darwinian selection in tumours
DP Cahill, KW Kinzler, B Vogelstein, C Lengauer
Trends in Genetics 15 (12), M57-M60, 1999
10651999
Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets
PK Brastianos, SL Carter, S Santagata, DP Cahill, A Taylor-Weiner, ...
Cancer discovery 5 (11), 1164-1177, 2015
10162015
Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma
I Tirosh, AS Venteicher, C Hebert, LE Escalante, AP Patel, K Yizhak, ...
Nature 539 (7628), 309-313, 2016
10012016
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells
ML Suvà, E Rheinbay, SM Gillespie, AP Patel, H Wakimoto, SD Rabkin, ...
Cell 157 (3), 580-594, 2014
9302014
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
AS Venteicher, I Tirosh, C Hebert, K Yizhak, C Neftel, MG Filbin, ...
Science 355 (6332), eaai8478, 2017
8692017
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma
M Snuderl, L Fazlollahi, LP Le, M Nitta, BH Zhelyazkova, CJ Davidson, ...
Cancer cell 20 (6), 810-817, 2011
7912011
Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial
A Mahajan, S Ahmed, MF McAleer, JS Weinberg, J Li, P Brown, S Settle, ...
The lancet oncology 18 (8), 1040-1048, 2017
6722017
Mutations in CIC and FUBP1 contribute to human oligodendroglioma
C Bettegowda, N Agrawal, Y Jiao, M Sausen, LD Wood, RH Hruban, ...
Science 333 (6048), 1453-1455, 2011
6172011
A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy
C Hunter, R Smith, DP Cahill, P Stephens, C Stevens, J Teague, ...
Cancer research 66 (8), 3987-3991, 2006
4962006
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment
DP Cahill, KK Levine, RA Betensky, PJ Codd, CA Romany, LB Reavie, ...
Clinical cancer research 13 (7), 2038-2045, 2007
4942007
Adaptive chromatin remodeling drives glioblastoma stem cell plasticity and drug tolerance
BB Liau, C Sievers, LK Donohue, SM Gillespie, WA Flavahan, TE Miller, ...
Cell stem cell 20 (2), 233-246. e7, 2017
4862017
IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resection
J Beiko, D Suki, KR Hess, BD Fox, V Cheung, M Cabral, N Shonka, ...
Neuro-oncology 16 (1), 81-91, 2014
4722014
MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance
S Yip, J Miao, DP Cahill, AJ Iafrate, K Aldape, CL Nutt, DN Louis
Clinical cancer research 15 (14), 4622-4629, 2009
4722009
Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate
L Bunse, S Pusch, T Bunse, F Sahm, K Sanghvi, M Friedrich, D Alansary, ...
Nature medicine 24 (8), 1192-1203, 2018
4382018
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