Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 2610 | 2018 |
Synaptic proximity enables NMDAR signalling to promote brain metastasis Q Zeng, IP Michael, P Zhang, S Saghafinia, G Knott, W Jiao, BD McCabe, ... Nature 573 (7775), 526-531, 2019 | 398 | 2019 |
Pan-cancer landscape of aberrant DNA methylation across human tumors S Saghafinia, M Mina, N Riggi, D Hanahan, G Ciriello Cell reports 25 (4), 1066-1080. e8, 2018 | 297 | 2018 |
Metabolic symbiosis enables adaptive resistance to anti-angiogenic therapy that is dependent on mTOR signaling E Allen, P Miéville, CM Warren, S Saghafinia, L Li, MW Peng, D Hanahan Cell Reports 15 (6), 1144-1160, 2016 | 212 | 2016 |
Conditional selection of genomic alterations dictates cancer evolution and oncogenic dependencies M Mina, F Raynaud, D Tavernari, E Battistello, S Sungalee, S Saghafinia, ... Cancer cell 32 (2), 155-168. e6, 2017 | 119 | 2017 |
A set of microRNAs coordinately controls tumorigenesis, invasion, and metastasis IP Michael, S Saghafinia, D Hanahan Proceedings of the National Academy of Sciences 116 (48), 24184-24195, 2019 | 44 | 2019 |
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx T Karasaki, DA Moore, S Veeriah, C Naceur-Lombardelli, A Toncheva, ... Nature medicine 29 (4), 833-845, 2023 | 40 | 2023 |
ALK7 signaling manifests a homeostatic tissue barrier that is abrogated during tumorigenesis and metastasis IP Michael, S Saghafinia, M Tichet, N Zangger, I Marinoni, A Perren, ... Developmental cell 49 (3), 409-424. e6, 2019 | 36 | 2019 |
Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion Q Zeng, S Saghafinia, A Chryplewicz, N Fournier, L Christe, YQ Xie, ... Science 378 (6621), eabl7207, 2022 | 34 | 2022 |
Performances evaluation of photo-Fenton process and sonolysis for the treatment of penicillin g formulation effluent MS Saghafinia, SM Emadian, M Vossoughi Procedia Environmental Sciences 8, 202-208, 2011 | 33 | 2011 |
Cancer cells retrace a stepwise differentiation program during malignant progression S Saghafinia, K Homicsko, A Di Domenico, S Wullschleger, A Perren, ... Cancer discovery 11 (10), 2638-2657, 2021 | 32* | 2021 |
A miR-375/YAP axis regulates neuroendocrine differentiation and tumorigenesis in lung carcinoid cells X Yang, J Nanayakkara, D Claypool, S Saghafinia, JJM Wong, M Xu, ... Scientific reports 11 (1), 10455, 2021 | 14 | 2021 |
Interrogating functional dependencies between genomic alterations can facilitate precision medicine approaches in cancer M Mina, F Raynaud, D Tavernari, E Battistello, S Sungalee, S Saghafinia, ... Annals of Oncology 28, vii2, 2017 | 1 | 2017 |
28P Identification of convergent gene repression mechanisms through integrative genomic and DNA methylation analysis in NSCLC C Castignani, F Gimeno-Valiente, EL Cadieux, K Chen, N Mensah, ... Annals of Oncology 33, S555, 2022 | | 2022 |
Evolutionary characterisation of lung adenocarcinoma pathological subtypes in TRACERx T Karasaki, DA Moore, S Veeriah, C Naceur-Lombardelli, A Toncheva, ... Cancer Research 82 (12_Supplement), 6091-6091, 2022 | | 2022 |
Tumour cells mirror embryonic developmental programs to acquire invasive and metastatic capabilities S Saghafinia, I Michael, K Homicsko, D Hanahan Annals of Oncology 30, vii2, 2019 | | 2019 |
Systematic identification of epigenetic alterations across human cancers therapeutic targets in cancer S Saghafinia, M Mina, D Hanahan, G Ciriello Annals of Oncology 28, vii14, 2017 | | 2017 |