DNA minor groove binders as potential antitumor and antimicrobial agents PG Baraldi, A Bovero, F Fruttarolo, D Preti, MA Tabrizi, MG Pavani, ... Medicinal research reviews 24 (4), 475-528, 2004 | 484 | 2004 |
Adenosine receptor antagonists: translating medicinal chemistry and pharmacology into clinical utility PG Baraldi, MA Tabrizi, S Gessi, PA Borea Chemical reviews 108 (1), 238-263, 2008 | 290 | 2008 |
A glance at adenosine receptors: novel target for antitumor therapy S Merighi, P Mirandola, K Varani, S Gessi, E Leung, PG Baraldi, ... Pharmacology & therapeutics 100 (1), 31-48, 2003 | 276 | 2003 |
The A3 adenosine receptor: history and perspectives PA Borea, K Varani, F Vincenzi, PG Baraldi, MA Tabrizi, S Merighi, ... Pharmacological reviews 67 (1), 74-102, 2015 | 268 | 2015 |
Synthesis and evaluation of 1, 5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity R Romagnoli, PG Baraldi, MK Salvador, D Preti, M Aghazadeh Tabrizi, ... Journal of medicinal chemistry 55 (1), 475-488, 2012 | 183 | 2012 |
Synthesis and biological evaluation of 2-and 3-aminobenzo [b] thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization R Romagnoli, PG Baraldi, MD Carrion, CL Cara, D Preti, F Fruttarolo, ... Journal of medicinal chemistry 50 (9), 2273-2277, 2007 | 180 | 2007 |
A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy KA Jacobson, S Merighi, K Varani, PA Borea, S Baraldi, ... Medicinal research reviews 38 (4), 1031-1072, 2018 | 148 | 2018 |
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists PG Baraldi, MA Tabrizi, D Preti, A Bovero, R Romagnoli, F Fruttarolo, ... Journal of medicinal chemistry 47 (6), 1434-1447, 2004 | 135 | 2004 |
Medicinal chemistry, pharmacology, and clinical implications of TRPV1 receptor antagonists M Aghazadeh Tabrizi, PG Baraldi, S Baraldi, S Gessi, S Merighi, ... Medicinal research reviews 37 (4), 936-983, 2017 | 126 | 2017 |
Medicinal Chemistry, Pharmacology, and Potential Therapeutic Benefits of Cannabinoid CB2 Receptor Agonists M Aghazadeh Tabrizi, PG Baraldi, PA Borea, K Varani Chemical reviews 116 (2), 519-560, 2016 | 119 | 2016 |
Synthesis and biological evaluation of 1-methyl-2-(3′, 4′, 5′-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors R Romagnoli, PG Baraldi, T Sarkar, MD Carrion, CL Cara, O Cruz-Lopez, ... Journal of medicinal chemistry 51 (5), 1464-1468, 2008 | 119 | 2008 |
Synthesis and Biological Evaluation of 2-(Alkoxycarbonyl)-3-Anilinobenzo[b]thiophenes and Thieno[2,3-b]pyridines as New Potent Anticancer Agents R Romagnoli, PG Baraldi, M Kimatrai Salvador, D Preti, ... Journal of medicinal chemistry 56 (6), 2606-2618, 2013 | 111 | 2013 |
Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI … PG Baraldi, G Balboni, MG Pavani, G Spalluto, MA Tabrizi, ED Clercq, ... Journal of medicinal chemistry 44 (16), 2536-2543, 2001 | 109 | 2001 |
Design, synthesis, and biological evaluation of C9-and C2-substituted pyrazolo [4, 3-e]-1, 2, 4-triazolo [1, 5-c] pyrimidines as new A2A and A3 adenosine receptors antagonists PG Baraldi, F Fruttarolo, MA Tabrizi, D Preti, R Romagnoli, H El-Kashef, ... Journal of medicinal chemistry 46 (7), 1229-1241, 2003 | 98 | 2003 |
Synthesis and biological effects of a new series of 2-amino-3-benzoylthiophenes as allosteric enhancers of A1-adenosine receptor PG Baraldi, AN Zaid, I Lampronti, F Fruttarolo, MG Pavani, MA Tabrizi, ... Bioorganic & medicinal chemistry letters 10 (17), 1953-1957, 2000 | 98 | 2000 |
Blockade of adenosine A2A receptors antagonizes parkinsonian tremor in the rat tacrine model by an action on specific striatal regions N Simola, S Fenu, PG Baraldi, MA Tabrizi, M Morelli Experimental neurology 189 (1), 182-188, 2004 | 94 | 2004 |
New strategies for the synthesis of A3 adenosine receptor antagonists PG Baraldi, A Bovero, F Fruttarolo, R Romagnoli, MA Tabrizi, D Preti, ... Bioorganic & medicinal chemistry 11 (19), 4161-4169, 2003 | 93 | 2003 |
A2B and A3 adenosine receptors modulate vascular endothelial growth factor and interleukin-8 expression in human melanoma cells treated with etoposide and doxorubicin S Merighi, C Simioni, S Gessi, K Varani, P Mirandola, MA Tabrizi, ... Neoplasia 11 (10), 1064-1073, 2009 | 89 | 2009 |
Design, synthesis, and biological evaluation of hybrid molecules containing α-methylene-γ-butyrolactones and polypyrrole minor groove binders PG Baraldi, M del Carmen Nunez, MA Tabrizi, E De Clercq, J Balzarini, ... Journal of medicinal chemistry 47 (11), 2877-2886, 2004 | 89 | 2004 |
N6-[(Hetero) aryl/(cyclo) alkyl-carbamoyl-methoxy-phenyl]-(2-chloro)-5′-N-ethylcarboxamido-adenosines: The first example of adenosine-related structures with potent agonist … PG Baraldi, D Preti, MA Tabrizi, F Fruttarolo, G Saponaro, S Baraldi, ... Bioorganic & medicinal chemistry 15 (7), 2514-2527, 2007 | 87 | 2007 |