Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing JM Replogle, TM Norman, A Xu, JA Hussmann, J Chen, JZ Cogan, ... Nature biotechnology 38 (8), 954-961, 2020 | 309 | 2020 |
Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ LJ Alvarado, HD Huntsman, H Cheng, DM Townsley, T Winkler, X Feng, ... Blood, The Journal of the American Society of Hematology 133 (19), 2043-2055, 2019 | 108 | 2019 |
Commensal microbiota drive the functional diversification of colon macrophages B Kang, LJ Alvarado, T Kim, ML Lehmann, H Cho, J He, P Li, BH Kim, ... Mucosal immunology 13 (2), 216-229, 2020 | 96 | 2020 |
Regio‐selective chemical‐enzymatic synthesis of pyrimidine nucleotides facilitates RNA structure and dynamics studies LJ Alvarado, RM LeBlanc, AP Longhini, SC Keane, N Jain, ZF Yildiz, ... ChemBioChem 15 (11), 1573-1577, 2014 | 52 | 2014 |
Heterodimerization of TPO and IFNγ impairs human hematopoietic stem/progenitor cell signaling and survival in chronic inflammation LJ Alvarado, A Andreoni, HD Huntsman, H Cheng, JR Knutson, ... Blood 130, 4, 2017 | 36 | 2017 |
Chemo-enzymatic synthesis of selectively 13C/15N-labeled RNA for NMR structural and dynamics studies LJ Alvarado, AP Longhini, RM LeBlanc, B Chen, C Kreutz, TK Dayie Methods in enzymology 549, 133-162, 2014 | 32 | 2014 |
Expression, purification and analysis of the activity of enzymes from the pentose phosphate pathway PK Arthur, LJ Alvarado, TK Dayie Protein expression and purification 76 (2), 229-237, 2011 | 32 | 2011 |
Supramolecular assemblies prepared from an iron (II) tripodal complex, tetrafluoroborate, and alkali metal cations. The effect of cation size on coordination number, anion … L Alvarado, C Brewer, G Brewer, RJ Butcher, A Straka, C Viragh CrystEngComm 11 (11), 2297-2307, 2009 | 20 | 2009 |
Eltrombopag promotes DNA repair in human hematopoietic stem and progenitor cells KL Guenther, PS Cheruku, A Cash, RH Smith, LJ Alvarado, S Burkett, ... Experimental hematology 73, 1-6. e6, 2019 | 17 | 2019 |
NOTCH-mediated ex vivo expansion of human hematopoietic stem and progenitor cells by culture under hypoxia D Araki, JF Fu, H Huntsman, S Cordes, F Seifuddin, LJ Alvarado, ... Stem Cell Reports 16 (9), 2336-2350, 2021 | 15 | 2021 |
Synthesis, structure and supramolecular features of homonuclear iron (III) and heteronuclear iron (III)–cobalt (III) complexes,[FeH3L][ML](ClO4) 3 (M= Fe (III) or Co (III). 2D … G Brewer, LJ Alvarado, CT Brewer, RJ Butcher, J Cipressi, C Viragh, ... Inorganica Chimica Acta 421, 100-109, 2014 | 15 | 2014 |
Use of acid–base and redox chemistry to synthesize cobalt (III) and iron (III) complexes of a partially deprotonated triprotic imidazole-containing Schiff base ligand: Hydrogen … L Alvarado, G Brewer, EE Carpenter, C Viragh, PY Zavalij Inorganica Chimica Acta 363 (4), 817-822, 2010 | 12 | 2010 |
Interferon-γ perturbs key signaling pathways induced by thrombopoietin, but not eltrombopag, in human hematopoietic stem/progenitor cells H Cheng, PS Cheruku, L Alvarado, A Cash, CE Dunbar, NS Young, ... Blood 128 (22), 3870, 2016 | 9 | 2016 |
IFN-γ directly inhibits the activity of erythropoietin in human erythroid progenitors D Araki, LJ Alvarado, HD Huntsman, RH Smith, A Larochelle Blood cells, molecules & diseases 85, 102488, 2020 | 4 | 2020 |
Synthesis, structure and supramolecular features of heteronuclear iron (III)–copper (II) complexes of a tripodal imidazole containing ligand G Brewer, LJ Alvarado, S Lear, C Viragh, PY Zavalij Inorganica Chimica Acta 439, 111-116, 2016 | 3 | 2016 |
Preclinical evaluation of foamy virus vector-mediated gene addition in human hematopoietic stem/progenitor cells for correction of leukocyte adhesion deficiency type 1 RH Smith, H Bloomer, D Fink, K Keyvanfar, M Nasimuzzaman, ... Human Gene Therapy 33 (23-24), 1293-1304, 2022 | 2 | 2022 |
Site-specific interaction of doxorubicin in the iron responsive element RNA: Implications in cellular iron homeostasis and non-iron deficiency anemia LJ Alvarado University of Maryland, College Park, 2014 | 1 | 2014 |
Notch-Mediated Expansion of Human Hematopoietic Stem and Progenitor Cells By Culture Under Hypoxia D Araki, S Cordes, F Seifuddin, LJ Alvarado, M Pirooznia, RH Smith, ... Blood 136, 28-29, 2020 | | 2020 |
Single-cell mRNA analysis of colon phagocyte heterogeneity identifies two major macrophage developmental pathways B Kang, LJ Alvarado, M Lehman, BH Kim, P Li, H Cho, J He, A Larochelle, ... The Journal of Immunology 202 (1_Supplement), 67.11-67.11, 2019 | | 2019 |
Concurrent Ex Vivo Differentiation of a Vascular Niche and Hematopoietic Stem/Progenitor Cells from Human iPSCs JP Ruiz, G Chen, M Drakopoulos, LJ Alvarado, M Boehm, A Larochelle Blood 130, 1162, 2017 | | 2017 |