Deacetylase inhibition promotes the generation and function of regulatory T cells R Tao, EF De Zoeten, E Özkaynak, C Chen, L Wang, PM Porrett, B Li, ... Nature medicine 13 (11), 1299-1307, 2007 | 1027 | 2007 |
Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa ET Clambey, EN McNamee, JA Westrich, LE Glover, EL Campbell, ... Proceedings of the National Academy of Sciences 109 (41), E2784-E2793, 2012 | 598 | 2012 |
Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3+ T-regulatory cells EF de Zoeten, L Wang, K Butler, UH Beier, T Akimova, H Sai, JE Bradner, ... Molecular and cellular biology, 2011 | 283 | 2011 |
Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice EF De Zoeten, L Wang, H Sai, WH Dillmann, WW Hancock Gastroenterology 138 (2), 583-594, 2010 | 262 | 2010 |
Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells L Wang, EF De Zoeten, MI Greene, WW Hancock Nature reviews Drug discovery 8 (12), 969-981, 2009 | 237 | 2009 |
Diagnosis and treatment of perianal Crohn disease: NASPGHAN clinical report and consensus statement EF de Zoeten, BA Pasternak, P Mattei, RE Kramer, HA Kader Journal of pediatric gastroenterology and nutrition 57 (3), 401-412, 2013 | 141 | 2013 |
Challenges in IBD research: precision medicine LA Denson, M Curran, DPB McGovern, WA Koltun, RH Duerr, SC Kim, ... Inflammatory bowel diseases 25 (Supplement_2), S31-S39, 2019 | 89 | 2019 |
A novel human IL2RB mutation results in T and NK cell–driven immune dysregulation IZ Fernandez, RM Baxter, JE Garcia-Perez, E Vendrame, T Ranganath, ... Journal of Experimental Medicine 216 (6), 1255-1267, 2019 | 87 | 2019 |
Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis CM Aherne, B Saeedi, CB Collins, JC Masterson, EN McNamee, ... Mucosal immunology 8 (6), 1324-1338, 2015 | 87 | 2015 |
Eosinophils and IL-33 perpetuate chronic inflammation and fibrosis in a pediatric population with stricturing Crohn's ileitis JC Masterson, KE Capocelli, L Hosford, K Biette, EN McNamee, ... Inflammatory bowel diseases 21 (10), 2429-2440, 2015 | 71 | 2015 |
A novel method to enhance informed consent: a prospective and randomised trial of form-based versus electronic assisted informed consent in paediatric endoscopy JA Friedlander, GS Loeben, PK Finnegan, AE Puma, X Zhang, ... Journal of medical ethics 37 (4), 194-200, 2011 | 64 | 2011 |
Limited expression of APRIL and its receptors prior to intestinal IgA plasma cell development during human infancy CE Gustafson, D Higbee, AR Yeckes, CC Wilson, EF De Zoeten, ... Mucosal immunology 7 (3), 467-477, 2014 | 60 | 2014 |
Prolongation of survival of mice with glioma treated with semiallogeneic fibroblasts secreting interleukin-2 RP Glick, T Lichtor, E de Zoeten, P Deshmukh, EP Cohen Neurosurgery 45 (4), 867, 1999 | 53 | 1999 |
Challenges in IBD research: update on progress and prioritization of the CCFA's research agenda LA Denson, MD Long, DPB McGovern, S Kugathasan, GD Wu, VB Young, ... Inflammatory bowel diseases 19 (4), 677-682, 2013 | 52 | 2013 |
Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function CB Collins, CM Aherne, A Yeckes, K Pound, HK Eltzschig, P Jedlicka, ... Mucosal immunology 6 (5), 960-971, 2013 | 51 | 2013 |
Regulatory T cells suppress CD4+ T cells through NFAT‐dependent transcriptional mechanisms DS Shin, A Jordan, S Basu, RM Thomas, S Bandyopadhyay, ... EMBO reports 15 (9), 991-999, 2014 | 48 | 2014 |
Alpha-1-antitrypsin therapy ameliorates acute colitis and chronic murine ileitis CB Collins, CM Aherne, SF Ehrentraut, ME Gerich, EN McNamee, ... Inflammatory Bowel Diseases 19 (9), 1964-1973, 2013 | 48 | 2013 |
Histone deacetylase inhibitors and transplantation R Tao, EF de Zoeten, E Ozkaynak, L Wang, B Li, MI Greene, AD Wells, ... Current opinion in immunology 19 (5), 589-595, 2007 | 48 | 2007 |
An intragastric fecal microbiota transplantation program for treatment of recurrent Clostridium difficile in children is efficacious, safe, and inexpensive DE Brumbaugh, EF De Zoeten, A Pyo-Twist, S Fidanza, S Hughes, ... The Journal of pediatrics 194, 123-127. e1, 2018 | 46 | 2018 |
Foxp3 processing by proprotein convertases and control of regulatory T cell function EF de Zoeten, I Lee, L Wang, C Chen, G Ge, AD Wells, WW Hancock, ... Journal of Biological Chemistry 284 (9), 5709-5716, 2009 | 41 | 2009 |