Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands M Kvansakul, H Yang, WD Fairlie, PE Czabotar, SF Fischer, MA Perugini, ... Cell Death & Differentiation 15 (10), 1564-1571, 2008 | 293 | 2008 |
Phosphoinositide-mediated oligomerization of a defensin induces cell lysis IKH Poon, AA Baxter, FT Lay, GD Mills, CG Adda, JAE Payne, TK Phan, ... Elife 3, e01808, 2014 | 197 | 2014 |
Structure of a thrombospondin C‐terminal fragment reveals a novel calcium core in the type 3 repeats M Kvansakul, JC Adams, E Hohenester The EMBO journal 23 (6), 1223-1233, 2004 | 181 | 2004 |
The Bcl-2 family: structures, interactions and targets for drug discovery M Kvansakul, MG Hinds Apoptosis 20, 136-150, 2015 | 169 | 2015 |
Structural biology of the Bcl-2 family and its mimicry by viral proteins M Kvansakul, MG Hinds Cell death & disease 4 (11), e909-e909, 2013 | 162 | 2013 |
Crystallographic insight into collagen recognition by discoidin domain receptor 2 F Carafoli, D Bihan, S Stathopoulos, AD Konitsiotis, M Kvansakul, ... Structure 17 (12), 1573-1581, 2009 | 149 | 2009 |
A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak M Kvansakul, MF van Delft, EF Lee, JM Gulbis, WD Fairlie, DCS Huang, ... Molecular cell 25 (6), 933-942, 2007 | 147 | 2007 |
The scribble cell polarity module in the regulation of cell signaling in tissue development and tumorigenesis R Stephens, K Lim, M Portela, M Kvansakul, PO Humbert, HE Richardson Journal of molecular biology 430 (19), 3585-3612, 2018 | 140 | 2018 |
Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1 M Kvansakul, AH Wei, JI Fletcher, SN Willis, L Chen, AW Roberts, ... PLoS pathogens 6 (12), e1001236, 2010 | 128 | 2010 |
Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects AA Baxter, FT Lay, IKH Poon, M Kvansakul, MD Hulett Cellular and Molecular Life Sciences 74 (20), 3809-3825, 2017 | 122 | 2017 |
Insight into Schmid metaphyseal chondrodysplasia from the crystal structure of the collagen X NC1 domain trimer O Bogin, M Kvansakul, E Rom, J Singer, A Yayon, E Hohenester Structure 10 (2), 165-173, 2002 | 121 | 2002 |
The Bcl-2 family: ancient origins, conserved structures, and divergent mechanisms S Banjara, CD Suraweera, MG Hinds, M Kvansakul Biomolecules 10 (1), 128, 2020 | 120 | 2020 |
The Bcl-2 family in host-virus interactions M Kvansakul, S Caria, MG Hinds Viruses 9 (10), 290, 2017 | 115 | 2017 |
Data publication with the structural biology data grid supports live analysis PA Meyer, S Socias, J Key, E Ransey, EC Tjon, A Buschiazzo, M Lei, ... Nature communications 7 (1), 10882, 2016 | 111 | 2016 |
Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission V Richter, CS Palmer, LD Osellame, AP Singh, K Elgass, DA Stroud, ... Journal of Cell Biology 204 (4), 477-486, 2014 | 111 | 2014 |
The tomato defensin TPP3 binds phosphatidylinositol (4, 5)-bisphosphate via a conserved dimeric cationic grip conformation to mediate cell lysis AA Baxter, V Richter, FT Lay, IKH Poon, CG Adda, PK Veneer, TK Phan, ... Molecular and cellular biology, 2015 | 98 | 2015 |
Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis SF Fischer, H Ludwig, J Holzapfel, M Kvansakul, L Chen, DCS Huang, ... Cell Death & Differentiation 13 (1), 109-118, 2006 | 92 | 2006 |
Dimerization of plant defensin NaD1 enhances its antifungal activity FT Lay, GD Mills, IKH Poon, NP Cowieson, N Kirby, AA Baxter, ... Journal of Biological Chemistry 287 (24), 19961-19972, 2012 | 88 | 2012 |
NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression J Ju, A Chen, Y Deng, M Liu, Y Wang, Y Wang, M Nie, C Wang, H Ding, ... Nature communications 8 (1), 928, 2017 | 80 | 2017 |
Structural insight into African swine fever virus A179L-mediated inhibition of apoptosis S Banjara, S Caria, LK Dixon, MG Hinds, M Kvansakul Journal of virology 91 (6), 10.1128/jvi. 02228-16, 2017 | 77 | 2017 |