| Restricted location of PSEN2/γ-secretase determines substrate specificity and generates an intracellular Aβ pool R Sannerud, C Esselens, P Ejsmont, R Mattera, L Rochin, ... Cell 166 (1), 193-208, 2016 | 333 | 2016 |
| A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency AK Tharkeshwar, J Trekker, W Vermeire, J Pauwels, R Sannerud, ... Scientific reports 7 (1), 41408, 2017 | 120 | 2017 |
| C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels J Beckers, AK Tharkeshwar, P Van Damme Autophagy 17 (11), 3306-3322, 2021 | 91 | 2021 |
| ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling W Hancock-Cerutti, Z Wu, P Xu, N Yadavalli, M Leonzino, ... Journal of Cell Biology 221 (7), e202106046, 2022 | 63 | 2022 |
| PQLC2 recruits the C9orf72 complex to lysosomes in response to cationic amino acid starvation J Amick, AK Tharkeshwar, G Talaia, SM Ferguson Journal of Cell Biology 219 (1), 2020 | 53 | 2020 |
| A novel strategy for the comprehensive analysis of the biomolecular composition of isolated plasma membranes DB Thimiri Govinda Raj, B Ghesquiere, AK Tharkeshwar, K Coen, ... Molecular Systems Biology 7 (1), 541, 2011 | 48 | 2011 |
| WDR41 supports lysosomal response to changes in amino acid availability J Amick, AK Tharkeshwar, C Amaya, SM Ferguson Molecular Biology of the Cell 29 (18), 2213-2227, 2018 | 40 | 2018 |
| Characterization of influenza virus pseudotyped with ebolavirus glycoprotein JH Xiao, P Rijal, L Schimanski, AK Tharkeshwar, E Wright, W Annaert, ... Journal of Virology 92 (4), 10.1128/jvi. 00941-17, 2018 | 30 | 2018 |
| Organellar omics—a reviving strategy to untangle the biomolecular complexity of the cell AK Tharkeshwar, K Gevaert, W Annaert Proteomics 18 (5-6), 1700113, 2018 | 26 | 2018 |
| Superparamagnetic nanoparticles for lysosome isolation to identify spatial alterations in lysosomal protein and lipid composition AK Tharkeshwar, D Demedts, W Annaert STAR protocols 1 (3), 100122, 2020 | 13 | 2020 |
| A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons J Beckers, AK Tharkeshwar, L Fumagalli, M Contardo, E Van Schoor, ... Acta neuropathologica communications 11 (1), 151, 2023 | 11 | 2023 |
| PMP22 duplication dysregulates lipid homeostasis and plasma membrane organization in developing human Schwann cells R Prior, A Silva, T Vangansewinkel, J Idkowiak, AK Tharkeshwar, ... Brain, awae158, 2024 | 5 | 2024 |
| PQLC2 signals lysosomal cationic amino acid abundance to the C9orf72 complex J Amick, AK Tharkeshwar, G Talaia, SM Ferguson BioRxiv, 670034, 2019 | 5 | 2019 |
| Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs Y Zhu, T Burg, K Neyrinck, T Vervliet, F Nami, E Vervoort, K Ahuja, ... Acta Neuropathologica 147 (1), 6, 2024 | 3 | 2024 |
| Defective Schwann cell lipid metabolism alters plasma membrane dynamics in Charcot-Marie-Tooth disease 1A R Prior, A Silva, T Vangansewinkel, J Idkowiak, AK Tharkeshwar, ... bioRxiv, 2023.04. 02.535224, 2023 | 3 | 2023 |
| Front Cover: Organellar Omics–A Reviving Strategy to Untangle the Biomolecular Complexity of the Cell AK Tharkeshwar, K Gevaert, W Annaert PROTEOMICS 18 (5-6), 1870041, 2018 | 1 | 2018 |
| A pathogenic mutation in the ALS/FTD gene VCP induces mitochondrial hypermetabolism by modulating the permeability transition pore S Vanderhaeghe, J Prerad, AK Tharkeshwar, E Goethals, K Vints, ... Acta Neuropathologica Communications 12 (1), 161, 2024 | | 2024 |
| Correction to: Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs Y Zhu, T Burg, K Neyrinck, T Vervliet, F Nami, E Vervoort, K Ahuja, ... Acta Neuropathologica 147 (1), 99, 2024 | | 2024 |
| Purification of lysosomes using dextran-conjugated SPIONs W Hancock-Cerutti, AK Tharkeshwar, SM Ferguson, P De Camilli | | 2022 |
| Synthesis of colloidal dextran-conjugated superparamagnetic iron nanoparticles (SPIONs) W Hancock-Cerutti, AK Tharkeshwar, SM Ferguson, P De Camilli | | 2022 |
