| An atomic structure of human γ-secretase X Bai, C Yan, G Yang, P Lu, D Ma, L Sun, R Zhou, SHW Scheres, Y Shi Nature 525 (7568), 212-217, 2015 | 595 | 2015 |
| Three-dimensional structure of human γ-secretase P Lu, X Bai, D Ma, T Xie, C Yan, L Sun, G Yang, Y Zhao, R Zhou, ... Nature 512 (7513), 166-170, 2014 | 411 | 2014 |
| L-glutamine provides acid resistance for Escherichia coli through enzymatic release of ammonia P Lu, D Ma, Y Chen, Y Guo, GQ Chen, H Deng, Y Shi Cell research 23 (5), 635-644, 2013 | 225 | 2013 |
| Structure and mechanism of a glutamate–GABA antiporter D Ma, P Lu, C Yan, C Fan, P Yin, J Wang, Y Shi Nature 483 (7391), 632-636, 2012 | 221 | 2012 |
| Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein W Huang, W Choi, W Hu, N Mi, Q Guo, M Ma, M Liu, Y Tian, P Lu, ... Cell research 22 (3), 473-489, 2012 | 217 | 2012 |
| Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel Y Wang, Y Huang, J Wang, C Cheng, W Huang, P Lu, YN Xu, P Wang, ... Nature 462 (7272), 467-472, 2009 | 210 | 2009 |
| Programmable design of orthogonal protein heterodimers Z Chen, SE Boyken, M Jia, F Busch, D Flores-Solis, MJ Bick, P Lu, ... Nature 565 (7737), 106-111, 2019 | 181 | 2019 |
| Accurate computational design of multipass transmembrane proteins P Lu, D Min, F DiMaio, KY Wei, MD Vahey, SE Boyken, Z Chen, JA Fallas, ... Science 359 (6379), 1042-1046, 2018 | 176 | 2018 |
| Computational design of transmembrane pores C Xu, P Lu, TM Gamal El-Din, XY Pei, MC Johnson, A Uyeda, MJ Bick, ... Nature 585 (7823), 129-134, 2020 | 143 | 2020 |
| Crystal structure of a membrane-bound O-acyltransferase D Ma, Z Wang, CN Merrikh, KS Lang, P Lu, X Li, H Merrikh, Z Rao, W Xu Nature 562 (7726), 286-290, 2018 | 100 | 2018 |
| Crystal structure of the γ-secretase component nicastrin T Xie, C Yan, R Zhou, Y Zhao, L Sun, G Yang, P Lu, D Ma, Y Shi Proceedings of the National Academy of Sciences 111 (37), 13349-13354, 2014 | 83 | 2014 |
| Structural basis for gating pore current in periodic paralysis D Jiang, TM Gamal El-Din, C Ing, P Lu, R Pomes, N Zheng, WA Catterall Nature 557 (7706), 590-594, 2018 | 76 | 2018 |
| Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase P Lu, D Ma, C Yan, X Gong, M Du, Y Shi Proceedings of the National Academy of Sciences 111 (5), 1813-1818, 2014 | 70 | 2014 |
| Substrate selectivity of the acid-activated glutamate/γ-aminobutyric acid (GABA) antiporter GadC from Escherichia coli D Ma, P Lu, Y Shi Journal of Biological Chemistry 288 (21), 15148-15153, 2013 | 56 | 2013 |
| Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites P Hosseinzadeh, PR Watson, TW Craven, X Li, S Rettie, F Pardo-Avila, ... Nature Communications 12 (1), 3384, 2021 | 47 | 2021 |
| Cryo-EM structure of human Wntless in complex with Wnt3a Q Zhong, Y Zhao, F Ye, Z Xiao, G Huang, M Xu, Y Zhang, X Zhan, K Sun, ... Nature Communications 12 (1), 4541, 2021 | 24 | 2021 |
| Structure of the mRNA splicing complex component Cwc2: insights into RNA recognition P Lu, G Lu, C Yan, L Wang, W Li, P Yin Biochemical Journal 441 (2), 591-597, 2012 | 18 | 2012 |
| Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes JA Peruzzi, J Steinkühler, TQ Vu, TF Gunnels, VT Hu, P Lu, D Baker, ... Nature Communications 15 (1), 3162, 2024 | 7 | 2024 |
| Computational design of transmembrane proteins J Zhu, P Lu Current Opinion in Structural Biology 74, 102381, 2022 | 4 | 2022 |
| Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions JA Peruzzi, TF Gunnels, HI Edelstein, P Lu, D Baker, JN Leonard, ... bioRxiv, 2023.04. 29.538810, 2023 | 2 | 2023 |
Yigong ShiPrinceton University, Tsinghua University, Westlake University在 tsinghua.edu.cn 的电子邮件经过验证
