| Isolation by size of epithelial tumor cells: a new method for the immunomorphological and molecular characterization of circulating tumor cells G Vona, A Sabile, M Louha, V Sitruk, S Romana, K Schütze, F Capron, ... The American journal of pathology 156 (1), 57-63, 2000 | 1380 | 2000 |
| Induction of two different modes of cell death, apoptosis and necrosis, in rat liver after a single dose of thioacetamide. GM Ledda-Columbano, P Coni, M Curto, L Giacomini, G Faa, S Oliverio, ... The American journal of pathology 139 (5), 1099, 1991 | 253 | 1991 |
| Occurrence of cell death (apoptosis) during the involution of liver hyperplasia. A Columbano, GM Ledda-Columbano, PP Coni, G Faa, C Liguori, ... Laboratory Investigation; a Journal of Technical Methods and Pathology 52 (6 …, 1985 | 228 | 1985 |
| YAP activation is an early event and a potential therapeutic target in liver cancer development A Perra, MA Kowalik, E Ghiso, GM Ledda-Columbano, L Di Tommaso, ... Journal of hepatology 61 (5), 1088-1096, 2014 | 224 | 2014 |
| Increased ROS generation and p53 activation in α-lipoic acid-induced apoptosis of hepatoma cells G Simbula, A Columbano, GM Ledda-Columbano, L Sanna, M Deidda, ... Apoptosis 12, 113-123, 2007 | 186 | 2007 |
| Thyroid hormone (T3) and TRβ agonist GC‐1 inhibit/reverse nonalcoholic fatty liver in rats A Perra, G Simbula, M Simbula, M Pibiri, MA Kowalik, P Sulas, MT Cocco, ... The FASEB Journal 22 (8), 2981-2989, 2008 | 163 | 2008 |
| Cyclin D1 is an early target in hepatocyte proliferation induced by thyroid hormone (T3) M Pibiri, GM Ledda‐columbano, C Cossu, G Simbula, M Menegazzi, ... The FASEB Journal 15 (6), 1006-1013, 2001 | 158 | 2001 |
| Occurrence of cell death (apoptosis) in preneoplastic and neoplastic liver cells. A sequential study. A Columbano, GM Ledda-Columbano, PM Rao, S Rajalakshmi, ... The American journal of pathology 116 (3), 441, 1984 | 156 | 1984 |
| Progenitor‐derived hepatocellular carcinoma model in the rat JB Andersen, R Loi, A Perra, VM Factor, GM Ledda‐Columbano, ... Hepatology 51 (4), 1401-1409, 2010 | 145 | 2010 |
| Liver cell proliferation induced by a single dose of lead nitrate. A Columbano, GM Ledda, P Sirigu, T Perra, P Pani The American Journal of Pathology 110 (1), 83, 1983 | 138 | 1983 |
| MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular … A Petrelli, A Perra, D Cora, P Sulas, S Menegon, C Manca, C Migliore, ... Hepatology 59 (1), 228-241, 2014 | 133 | 2014 |
| In vivo hepatocyte proliferation is inducible through a TNF and IL-6-independent pathway GM Ledda-Columbano, M Curto, R Piga, AI Zedda, M Menegazzi, ... Oncogene 17 (8), 1039-1044, 1998 | 120 | 1998 |
| Rapid induction of apoptosis in rat liver by cycloheximide. GM Ledda-Columbano, P Coni, G Faa, G Manenti, A Columbano The American journal of pathology 140 (3), 545, 1992 | 117 | 1992 |
| Gadd45β is induced through a CAR‐dependent, TNF‐independent pathway in murine liver hyperplasia A Columbano, GM Ledda‐Columbano, M Pibiri, C Cossu, M Menegazzi, ... Hepatology 42 (5), 1118-1126, 2005 | 111 | 2005 |
| Nrf2, but not β‐catenin, mutation represents an early event in rat hepatocarcinogenesis P Zavattari, A Perra, S Menegon, MA Kowalik, A Petrelli, MM Angioni, ... Hepatology 62 (3), 851-862, 2015 | 104 | 2015 |
| A common set of immediate‐early response genes in liver regeneration and hyperplasia J Locker, J Tian, R Carver, D Concas, C Cossu, GM Ledda‐Columbano, ... Hepatology 38 (2), 314-325, 2003 | 104 | 2003 |
| Early increase in cyclin-D1 expression and accelerated entry of mouse hepatocytes into S phase after administration of the mitogen 1, 4-Bis [2-(3, 5-Dichloropyridyloxy)] benzene GM Ledda-Columbano, M Pibiri, R Loi, A Perra, H Shinozuka, ... The American journal of pathology 156 (1), 91-97, 2000 | 104 | 2000 |
| Cell proliferation induced by triiodothyronine in rat liver is associated with nodule regression and reduction of hepatocellular carcinomas GM Ledda-Columbano, A Perra, R Loi, H Shinozuka, A Columbano Cancer research 60 (3), 603-609, 2000 | 101 | 2000 |
| Yes‐associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice MA Kowalik, C Saliba, M Pibiri, A Perra, GM Ledda‐Columbano, I Sarotto, ... Hepatology 53 (6), 2086-2096, 2011 | 95 | 2011 |
| Cell proliferation and promotion of rat liver carcinogenesis: different effect of hepatic regeneration and mitogen induced hyperplasia on the development of enzyme-altered foci A Columbano, GM Ledda-Columbano, MG Ennas, M Curto, A Chelo, ... Carcinogenesis 11 (5), 771-776, 1990 | 93 | 1990 |
