Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain SC Cork, JE Richards, MK Holt, FM Gribble, F Reimann, S Trapp Molecular metabolism 4 (10), 718-731, 2015 | 377 | 2015 |
Preproglucagon neurons in the nucleus of the solitary tract are the main source of brain GLP-1, mediate stress-induced hypophagia, and limit unusually large intakes of food MK Holt, JE Richards, DR Cook, DI Brierley, DL Williams, F Reimann, ... Diabetes 68 (1), 21-33, 2019 | 152 | 2019 |
Central and peripheral GLP-1 systems independently suppress eating DI Brierley, MK Holt, A Singh, A de Araujo, M McDougle, M Vergara, ... Nature metabolism 3 (2), 258-273, 2021 | 143 | 2021 |
PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation JSL Yu, TS Ramasamy, N Murphy, MK Holt, R Czapiewski, SK Wei, W Cui Nature communications 6 (1), 7212, 2015 | 110 | 2015 |
Endogenous GLP-1 in lateral septum promotes satiety and suppresses motivation for food in mice SJ Terrill, MK Holt, CB Maske, N Abrams, F Reimann, S Trapp, ... Physiology & behavior 206, 191-199, 2019 | 43 | 2019 |
The physiological role of the brain GLP-1 system in stress MK Holt, S Trapp Cogent Biology 2 (1), 1229086, 2016 | 43 | 2016 |
Synaptic inputs to the mouse dorsal vagal complex and its resident preproglucagon neurons MK Holt, LE Pomeranz, KT Beier, F Reimann, FM Gribble, L Rinaman Journal of Neuroscience 39 (49), 9767-9781, 2019 | 31 | 2019 |
The role of nucleus of the solitary tract glucagon‐like peptide‐1 and prolactin‐releasing peptide neurons in stress: anatomy, physiology and cellular interactions MK Holt, L Rinaman British Journal of Pharmacology, 2021 | 28* | 2021 |
Serotonergic modulation of the activity of GLP-1 producing neurons in the nucleus of the solitary tract in mouse MK Holt, IJ Llewellyn-Smith, F Reimann, FM Gribble, S Trapp Molecular metabolism 6 (8), 909-921, 2017 | 28 | 2017 |
Preproglucagon neurons in the hindbrain have IL-6 receptor-α and show Ca2+ influx in response to IL-6 F Anesten, MK Holt, E Schéle, V Pálsdóttir, F Reimann, FM Gribble, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2016 | 23 | 2016 |
PPG neurons in the nucleus of the solitary tract modulate heart rate but do not mediate GLP-1 receptor agonist-induced tachycardia in mice MK Holt, DR Cook, DI Brierley, JE Richards, F Reimann, AV Gourine, ... Molecular Metabolism 39, 101024, 2020 | 22 | 2020 |
The ins and outs of the caudal nucleus of the solitary tract: An overview of cellular populations and anatomical connections MK Holt Journal of Neuroendocrinology 34 (6), e13132, 2022 | 16 | 2022 |
Mind affects matter: Hindbrain GLP1 neurons link stress, physiology and behaviour MK Holt Experimental Physiology 106 (9), 1853-1862, 2021 | 7 | 2021 |
Modulation of stress-related behaviour by hypothalamic engagement of preproglucagon neurons in the nucleus of the solitary tract MK Holt, N Valderrama, MJ Polanco, L Rinaman bioRxiv, 2022.02. 04.479117, 2022 | 2 | 2022 |
A neuronal circuit driven by GLP-1 in the olfactory bulb regulates insulin secretion M Montaner, J Denom, V Simon, W Jiang, MK Holt, D Brierley, C Rouch, ... bioRxiv, 2023.08. 28.555086, 2023 | | 2023 |
Preproglucagon neurons of the nucleus solitarius are the major producers of GLP-1 in the brain, mediating stress-induced suppression of food intake and limiting abnormal binge … MK Holt, J Richards, DR Cook, DI Brierley, DL Williams, F Reimann, ... Diabetes: A Journal of the American Diabetes Association 12 (4), 2-14, 2019 | | 2019 |
孤束核のプレプログルカゴンニューロンは脳内 GLP-1 の主要な産生細胞であり, ストレス誘発性の摂食抑制を仲介し, 異常な大量摂食を制限する MK Holt, JE Richards, DR Cook, DI Brierley, DL Williams, F Reimann, ... Diabetes: a journal of the American Diabetes Association 12 (4), 2-14, 2019 | | 2019 |
In vitro and in vivo properties of GLP-1 producing neurons: The brain actions of a gut hormone MKB Holt UCL (University College London), 2017 | | 2017 |
Rodent models of diabetes: pathogenesis and complications DR Cook, MK Holt, JE Richards, S Trapp | | 2017 |
Articles in PresS. Am J Physiol Regul Integr Comp Physiol (April 20, 2016). doi: 10.1152/ajpregu. 00383.2015 F Anesten, MK Holt, E Schéle, V Pálsdóttir, F Reimann, JO Jansson | | 2016 |