Simultaneous repression of multiple bacterial genes using nonrepetitive extra-long sgRNA arrays AC Reis, SM Halper, GE Vezeau, DP Cetnar, A Hossain, PR Clauer, ... Nature biotechnology 37 (11), 1294-1301, 2019 | 131 | 2019 |
Automated design of thousands of nonrepetitive parts for engineering stable genetic systems A Hossain, E Lopez, SM Halper, DP Cetnar, AC Reis, D Strickland, ... Nature biotechnology 38 (12), 1466-1475, 2020 | 99 | 2020 |
Synthesis success calculator: predicting the rapid synthesis of DNA fragments with machine learning SM Halper, A Hossain, HM Salis ACS Synthetic Biology 9 (7), 1563-1571, 2020 | 15 | 2020 |
An automated pipeline for engineering many-enzyme pathways: computational sequence design, pathway expression-flux mapping, and scalable pathway optimization SM Halper, DP Cetnar, HM Salis Synthetic Metabolic Pathways: Methods and Protocols, 39-61, 2018 | 9 | 2018 |
Automated Parameterization of Predictive Kinetic Metabolic Models from Sparse Datasets for Efficient Optimization of Many-Enzyme Heterologous Pathways SM Halper, I Farasat, HM Salis bioRxiv, 161372, 2017 | 1 | 2017 |
A modular toolkit for environmental Rhodococcus, Gordonia, and Nocardia enables complex metabolic manipulation. Z Jansen, A Alameri, Q Wei, DL Kulhanek, AR Gilmour, S Halper, ... bioRxiv, 2024.02. 21.581484, 2024 | | 2024 |
Building a Scalable, Generalizable CRISPR Molecular Cloning Toolbox S Halper, N Schwalm, M Chu, R Pullen 5th International Conference on CRISPR Technologies, 2022 | | 2022 |
Engineered CRISPR/Cas9 Systems for Simultaneous Long-term Regulation of Multiple Targets H Salis, A Reis, S Halper, P Clauer, GE Vezeau, DP Cetnar, A Hossain US Patent App. 17/633,321, 2022 | | 2022 |
Machine Learning-Evolved Biophysical Models for Engineering Genetic Circuits and Pathways HM Salis, TL LaFleur, A Hossain, AC Reis, SM Halper, GE Vezeau, ... | | 2022 |
Development of an Experimental Pipeline for Onboarding of Actinobacteria with Rhodococcus ruber C208 as the Example N Schwalm III, RL Renberg, C Hellman, M Chu, SM Halper, RM Pullen, ... | | 2020 |
Design Optimization Algorithms for Synthetic Biology Applications S Halper The Pennsylvania State University, 2019 | | 2019 |