Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4 Z Yang, JHN Yik, R Chen, N He, MK Jang, K Ozato, Q Zhou Molecular cell 19 (4), 535-545, 2005 | 1245 | 2005 |
Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA JHN Yik, R Chen, R Nishimura, JL Jennings, AJ Link, Q Zhou Molecular cell 12 (4), 971-982, 2003 | 536 | 2003 |
The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation Q Zhou, JHN Yik Microbiology and Molecular Biology Reviews 70 (3), 646-659, 2006 | 331 | 2006 |
Glycans as endocytosis signals: the cases of the asialoglycoprotein and hyaluronan/chondroitin sulfate receptors PH Weigel, JHN Yik Biochimica et Biophysica Acta (BBA)-General Subjects 1572 (2-3), 341-363, 2002 | 289 | 2002 |
Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis BA Christiansen, MJ Anderson, CA Lee, JC Williams, JHN Yik, ... Osteoarthritis and cartilage 20 (7), 773-782, 2012 | 228 | 2012 |
Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription M Barboric, JHN Yik, N Czudnochowski, Z Yang, R Chen, X Contreras, ... Nucleic acids research 35 (6), 2003-2012, 2007 | 212 | 2007 |
Cartilage oligomeric matrix protein and its binding partners in the cartilage extracellular matrix: interaction, regulation and role in chondrogenesis C Acharya, JHN Yik, A Kishore, V Van Dinh, PE Di Cesare, ... Matrix Biology 37, 102-111, 2014 | 175 | 2014 |
A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated … JHN Yik, R Chen, AC Pezda, CS Samford, Q Zhou Molecular and Cellular Biology, 2004 | 145 | 2004 |
Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription JHN Yik, R Chen, AC Pezda, Q Zhou Journal of Biological Chemistry 280 (16), 16368-16376, 2005 | 119 | 2005 |
Enhanced activity of transforming growth factor β1 (TGF-β1) bound to cartilage oligomeric matrix protein DR Haudenschild, E Hong, JHN Yik, B Chromy, M Mörgelin, KD Snow, ... Journal of Biological Chemistry 286 (50), 43250-43258, 2011 | 87 | 2011 |
Brd4 and HEXIM1: Multiple Roles in P‐TEFb Regulation and Cancer R Chen, JHN Yik, QJ Lew, SH Chao BioMed research international 2014 (1), 232870, 2014 | 78 | 2014 |
Cartilage oligomeric matrix protein enhances osteogenesis by directly binding and activating bone morphogenetic protein-2 K Ishida, C Acharya, BA Christiansen, JHN Yik, PE DiCesare, ... Bone 55 (1), 23-35, 2013 | 61 | 2013 |
Comparative analysis with collagen type II distinguishes cartilage oligomeric matrix protein as a primary TGFβ-responsive gene H Li, DR Haudenschild, KL Posey, JT Hecht, PE Di Cesare, JHN Yik Osteoarthritis and cartilage 19 (10), 1246-1253, 2011 | 43 | 2011 |
Cyclin‐dependent kinase 9 inhibition protects cartilage from the catabolic effects of proinflammatory cytokines JHN Yik, Z Hu, R Kumari, BA Christiansen, DR Haudenschild Arthritis & Rheumatology 66 (6), 1537-1546, 2014 | 39 | 2014 |
The minor subunit splice variants, H2b and H2c, of the human asialoglycoprotein receptor are present with the major subunit H1 in different hetero-oligomeric receptor complexes JHN Yik, A Saxena, PH Weigel Journal of Biological Chemistry 277 (25), 23076-23083, 2002 | 39 | 2002 |
The influence of endplate morphology on cage subsidence in patients with stand-alone oblique lateral lumbar interbody fusion (OLIF) Z Hu, D He, J Gao, Z Zeng, C Jiang, W Ni, JHN Yik, X Zhao, S Fan Global Spine Journal 13 (1), 97-103, 2023 | 38 | 2023 |
In-vitro and in-vivo imaging of MMP activity in cartilage and joint injury T Fukui, E Tenborg, JHN Yik, DR Haudenschild Biochemical and Biophysical Research Communications 460 (3), 741-746, 2015 | 30 | 2015 |
CircSLC7A2 protects against osteoarthritis through inhibition of the miR‐4498/TIMP3 axis W Ni, C Jiang, Y Wu, H Zhang, L Wang, JHN Yik, DR Haudenschild, ... Cell proliferation 54 (6), e13047, 2021 | 26 | 2021 |
Inhibition of early response genes prevents changes in global joint metabolomic profiles in mouse post-traumatic osteoarthritis DR Haudenschild, AK Carlson, DL Zignego, JHN Yik, JK Hilmer, RK June Osteoarthritis and Cartilage 27 (3), 504-512, 2019 | 26 | 2019 |
Acute changes in NADPH oxidase 4 in early post‐traumatic osteoarthritis AM Wegner, NR Campos, MA Robbins, AF Haddad, HC Cunningham, ... Journal of Orthopaedic Research® 37 (11), 2429-2436, 2019 | 24 | 2019 |