关注
Katsuya Tsuchihara
Katsuya Tsuchihara
Director, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Japan
在 east.ncc.go.jp 的电子邮件经过验证
标题
引用次数
引用次数
年份
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
K Zaugg, Y Yao, PT Reilly, K Kannan, R Kiarash, J Mason, P Huang, ...
Genes & development 25 (10), 1041-1051, 2011
5322011
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions
R Tomasini, K Tsuchihara, M Wilhelm, M Fujitani, A Rufini, CC Cheung, ...
Genes & development 22 (19), 2677-2691, 2008
5172008
FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal
H You, M Pellegrini, K Tsuchihara, K Yamamoto, G Hacker, M Erlacher, ...
The Journal of experimental medicine 203 (7), 1657, 2006
5032006
Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation
K Sato, K Tsuchihara, S Fujii, M Sugiyama, T Goya, Y Atomi, T Ueno, ...
Cancer research 67 (20), 9677-9684, 2007
4232007
Vandetanib in patients with previously treated RET-rearranged advanced non-small-cell lung cancer (LURET): an open-label, multicentre phase 2 trial
K Yoh, T Seto, M Satouchi, M Nishio, N Yamamoto, H Murakami, ...
The Lancet Respiratory Medicine 5 (1), 42-50, 2017
3182017
Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer
T Kohno, T Nakaoku, K Tsuta, K Tsuchihara, S Matsumoto, K Yoh, K Goto
Translational lung cancer research 4 (2), 156, 2015
2932015
Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies
Y Nakamura, H Taniguchi, M Ikeda, H Bando, K Kato, C Morizane, T Esaki, ...
Nature medicine 26 (12), 1859-1864, 2020
2812020
Isoform-specific p73 knockout mice reveal a novel role for ΔNp73 in the DNA damage response pathway
MT Wilhelm, A Rufini, MK Wetzel, K Tsuchihara, S Inoue, R Tomasini, ...
Genes & development 24 (6), 549-560, 2010
2592010
ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress
W Assaily, DA Rubinger, K Wheaton, Y Lin, W Ma, W Xuan, ...
Molecular cell 44 (3), 491-501, 2011
2012011
Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma
H Makinoshima, M Takita, S Matsumoto, A Yagishita, S Owada, H Esumi, ...
Journal of Biological Chemistry 289 (30), 20813-20823, 2014
2002014
Signaling through the phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) axis is responsible for aerobic glycolysis mediated by glucose transporter in …
H Makinoshima, M Takita, K Saruwatari, S Umemura, Y Obata, G Ishii, ...
Journal of Biological Chemistry 290 (28), 17495-17504, 2015
1952015
Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis
S Umemura, S Mimaki, H Makinoshima, S Tada, G Ishii, H Ohmatsu, ...
Journal of Thoracic Oncology 9 (9), 1324-1331, 2014
1892014
Genomic profiling of large-cell neuroendocrine carcinoma of the lung
T Miyoshi, S Umemura, Y Matsumura, S Mimaki, S Tada, H Makinoshima, ...
Clinical Cancer Research 23 (3), 757-765, 2017
1812017
Autophagy and cancer: dynamism of the metabolism of tumor cells and tissues
K Tsuchihara, S Fujii, H Esumi
Cancer letters 278 (2), 130-138, 2009
1712009
TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity
R Tomasini, K Tsuchihara, C Tsuda, SK Lau, M Wilhelm, A Rufini, M Tsao, ...
Proceedings of the National Academy of Sciences 106 (3), 797-802, 2009
1632009
Specific interaction of polypyrimidine tract-binding protein with the extreme 3'-terminal structure of the hepatitis C virus genome, the 3'X
K Tsuchihara, T Tanaka, M Hijikata, S Kuge, H Toyoda, A Nomoto, ...
Journal of Virology 71 (9), 6720-6726, 1997
1581997
Amplification of EGFR wild-type alleles in non–small cell lung cancer cells confers acquired resistance to mutation-selective EGFR tyrosine kinase inhibitors
S Nukaga, H Yasuda, K Tsuchihara, J Hamamoto, K Masuzawa, I Kawada, ...
Cancer research 77 (8), 2078-2089, 2017
1532017
Hepatitis C virus core protein regulates cell growth and signal transduction pathway transmitting growth stimuli
K Tsuchihara, M Hijikata, K Fukuda, T Kuroki, N Yamamoto, ...
Virology 258 (1), 100-107, 1999
1491999
RET fusion gene: Translation to personalized lung cancer therapy
T Kohno, K Tsuta, K Tsuchihara, T Nakaoku, K Yoh, K Goto
Cancer science 104 (11), 1396-1400, 2013
1392013
Massive transcriptional start site analysis of human genes in hypoxia cells
K Tsuchihara, Y Suzuki, H Wakaguri, T Irie, K Tanimoto, S Hashimoto, ...
Nucleic acids research 37 (7), 2249-2263, 2009
1352009
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