Basal mitophagy occurs independently of PINK1 in mouse tissues of high metabolic demand TG McWilliams, AR Prescott, L Montava-Garriga, G Ball, F Singh, E Barini, ... Cell metabolism 27 (2), 439-449. e5, 2018 | 515 | 2018 |
Tetrahydrocannabinol induces brain mitochondrial respiratory chain dysfunction and increases oxidative stress: a potential mechanism involved in cannabis‐related stroke V Wolff, AI Schlagowski, O Rouyer, AL Charles, F Singh, C Auger, ... BioMed research international 2015 (1), 323706, 2015 | 140 | 2015 |
Avian erythrocytes have functional mitochondria, opening novel perspectives for birds as animal models in the study of ageing A Stier, P Bize, Q Schull, J Zoll, F Singh, B Geny, F Gros, C Royer, ... Frontiers in zoology 10, 1-9, 2013 | 128 | 2013 |
Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis F Singh, AL Charles, AI Schlagowski, J Bouitbir, A Bonifacio, F Piquard, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (7), 1574-1585, 2015 | 109 | 2015 |
Mitochondria: mitochondrial participation in ischemia–reperfusion injury in skeletal muscle A Lejay, A Meyer, AI Schlagowski, AL Charles, F Singh, J Bouitbir, ... The international journal of biochemistry & cell biology 50, 101-105, 2014 | 104 | 2014 |
Mechanisms of statin-associated skeletal muscle-associated symptoms J Bouitbir, GM Sanvee, MV Panajatovic, F Singh, S Krähenbühl Pharmacological research 154, 104201, 2020 | 102 | 2020 |
Phosphorylation of Parkin at serine 65 is essential for its activation in vivo TG McWilliams, E Barini, R Pohjolan-Pirhonen, SP Brooks, F Singh, ... Royal Society Open Biology 8 (11), 180108, 2018 | 102 | 2018 |
IFN-β-induced reactive oxygen species and mitochondrial damage contribute to muscle impairment and inflammation maintenance in dermatomyositis A Meyer, G Laverny, Y Allenbach, E Grelet, V Ueberschlag, ... Acta neuropathologica 134, 655-666, 2017 | 102 | 2017 |
Statins trigger mitochondrial reactive oxygen species-induced apoptosis in glycolytic skeletal muscle J Bouitbir, F Singh, AL Charles, AI Schlagowski, A Bonifacio, ... Antioxidants & redox signaling 24 (2), 84-98, 2016 | 95 | 2016 |
Pharmacological rescue of impaired mitophagy in Parkinson’s disease-related LRRK2 G2019S knock-in mice F Singh, AR Prescott, P Rosewell, G Ball, AD Reith, IG Ganley elife 10, e67604, 2021 | 75 | 2021 |
Discovery of XL01126: a potent, fast, cooperative, selective, orally bioavailable, and blood–brain barrier penetrant PROTAC degrader of leucine-rich repeat kinase 2 X Liu, AF Kalogeropulou, S Domingos, N Makukhin, RS Nirujogi, F Singh, ... Journal of the American Chemical Society 144 (37), 16930-16952, 2022 | 71 | 2022 |
Semi-automated quantitation of mitophagy in cells and tissues L Montava-Garriga, F Singh, G Ball, IG Ganley Mechanisms of ageing and development 185, 111196, 2020 | 53 | 2020 |
High reactive oxygen species in fibrotic and nonfibrotic skin of patients with diffuse cutaneous systemic sclerosis K Bourji, A Meyer, E Chatelus, J Pincemail, E Pigatto, JO Defraigne, ... Free Radical Biology and Medicine 87, 282-289, 2015 | 50 | 2015 |
Mitochondrial uncoupling reduces exercise capacity despite several skeletal muscle metabolic adaptations AI Schlagowski, F Singh, AL Charles, T Gali Ramamoorthy, F Favret, ... Journal of Applied Physiology 116 (4), 364-375, 2014 | 50 | 2014 |
Endothelial function does not improve with high-intensity continuous exercise training in SHR: implications of eNOS uncoupling S Battault, F Singh, S Gayrard, J Zoll, C Reboul, G Meyer Hypertension Research 39 (2), 70-78, 2016 | 43 | 2016 |
Impact of Type II LRRK2 inhibitors on signalling and mitophagy A Tasegian, F Singh, I Ganley, AD Reith, DR Alessi Biochemical Journal 478 (19), 3555–3573, 2021 | 42 | 2021 |
Carbon monoxide increases inducible NOS expression that mediates CO-induced myocardial damage during ischemia-reperfusion G Meyer, L André, A Kleindienst, F Singh, S Tanguy, S Richard, P Obert, ... American Journal of Physiology-Heart and Circulatory Physiology 308 (7 …, 2015 | 36 | 2015 |
Parkinson's disease and mitophagy: an emerging role for LRRK2 F Singh, IG Ganley Biochemical Society Transactions 49 (2), 551-562, 2021 | 35 | 2021 |
Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1 O Antico, A Ordureau, M Stevens, F Singh, RS Nirujogi, M Gierlinski, ... Science Advances 7 (46), eabj0722, 2021 | 30 | 2021 |
A new murine model of sustainable and durable chronic critical limb ischemia fairly mimicking human pathology A Lejay, P Choquet, F Thaveau, F Singh, A Schlagowski, AL Charles, ... European Journal of Vascular and Endovascular Surgery 49 (2), 205-212, 2015 | 28 | 2015 |