Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion K Hara, G Zheng, Q Qu, H Liu, Z Ouyang, Z Chen, DR Tomchick, H Yu Nature structural & molecular biology 21 (10), 864-870, 2014 | 184 | 2014 |
Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase ζ and REV1 K Hara, H Hashimoto, Y Murakumo, S Kobayashi, T Kogame, S Unzai, ... Journal of Biological Chemistry 285 (16), 12299-12307, 2010 | 145 | 2010 |
Structural basis of recruitment of DNA polymerase ζ by interaction between REV1 and REV7 proteins S Kikuchi, K Hara, T Shimizu, M Sato, H Hashimoto Journal of Biological Chemistry 287 (40), 33847-33852, 2012 | 113 | 2012 |
Crystallographic structures of two bisphosphonate: 1-deoxyxylulose-5-phosphate reductoisomerase complexes S Yajima, K Hara, JM Sanders, F Yin, K Ohsawa, J Wiesner, H Jomaa, ... Journal of the American Chemical Society 126 (35), 10824-10825, 2004 | 103 | 2004 |
Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin S Yajima, K Hara, D Iino, Y Sasaki, T Kuzuyama, K Ohsawa, H Seto Acta Crystallographica Section F: Structural Biology and Crystallization …, 2007 | 88 | 2007 |
Structure of a novel DNA-binding domain of helicase-like transcription factor (HLTF) and its functional implication in DNA damage tolerance A Hishiki, K Hara, Y Ikegaya, H Yokoyama, T Shimizu, M Sato, ... Journal of Biological Chemistry 290 (21), 13215-13223, 2015 | 86 | 2015 |
Crystal structure of zinc‐finger domain of Nanos and its functional implications H Hashimoto, K Hara, A Hishiki, S Kawaguchi, N Shichijo, K Nakamura, ... EMBO reports 11 (11), 848-853, 2010 | 51 | 2010 |
Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction ML Actis, ND Ambaye, BJ Evison, Y Shao, M Vanarotti, A Inoue, ... Bioorganic & medicinal chemistry 24 (18), 4339-4346, 2016 | 44 | 2016 |
Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels–Alderase M Sato, S Kishimoto, M Yokoyama, CS Jamieson, K Narita, N Maeda, ... Nature catalysis 4 (3), 223-232, 2021 | 42 | 2021 |
The transcription factor TFII-I promotes DNA translesion synthesis and genomic stability FJ Fattah, K Hara, KR Fattah, C Yang, N Wu, R Warrington, DJ Chen, ... PLoS genetics 10 (6), e1004419, 2014 | 42 | 2014 |
Dynamic feature of mitotic arrest deficient 2–like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment–maintaining phosphoprotein (CAMP) K Hara, S Taharazako, M Ikeda, H Fujita, Y Mikami, S Kikuchi, A Hishiki, ... Journal of Biological Chemistry 292 (43), 17658-17667, 2017 | 39 | 2017 |
Structure of proliferating cell nuclear antigen (PCNA) bound to an APIM peptide reveals the universality of PCNA interaction K Hara, M Uchida, R Tagata, H Yokoyama, Y Ishikawa, A Hishiki, ... Acta Crystallographica Section F: Structural Biology Communications 74 (4 …, 2018 | 30 | 2018 |
Purification, crystallization and initial X-ray diffraction study of human REV7 in complex with a REV3 fragment K Hara, T Shimizu, S Unzai, S Akashi, M Sato, H Hashimoto Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009 | 29 | 2009 |
Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis T Yamamoto, Y Tsunematsu, K Hara, T Suzuki, S Kishimoto, H Kawagishi, ... Angewandte Chemie 128 (21), 6315-6318, 2016 | 28 | 2016 |
Structural basis of HEAT‐kleisin interactions in the human condensin I subcomplex K Hara, K Kinoshita, T Migita, K Murakami, K Shimizu, K Takeuchi, ... EMBO reports 20 (5), e47183, 2019 | 26 | 2019 |
Enzymatic one-step ring contraction for quinolone biosynthesis S Kishimoto, K Hara, H Hashimoto, Y Hirayama, PA Champagne, ... Nature communications 9 (1), 2826, 2018 | 25 | 2018 |
Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive … T Saito, Y Shimizu, K Tsukakoshi, K Abe, J Lee, K Ueno, R Asano, ... Biosensors and Bioelectronics 203, 114027, 2022 | 22 | 2022 |
Specialized flavoprotein promotes sulfur migration and spiroaminal formation in aspirochlorine biosynthesis Y Tsunematsu, N Maeda, M Sato, K Hara, H Hashimoto, K Watanabe, ... Journal of the American Chemical Society 143 (1), 206-213, 2020 | 21 | 2020 |
Functional and Structural Analyses of trans C-Methyltransferase in Fungal Polyketide Biosynthesis S Kishimoto, Y Tsunematsu, T Matsushita, K Hara, H Hashimoto, Y Tang, ... Biochemistry 58 (38), 3933-3937, 2019 | 14 | 2019 |
Structural and thermodynamic basis of the enhanced interaction between kinesin spindle protein Eg5 and STLC-type inhibitors H Yokoyama, J Sawada, K Sato, N Ogo, N Kamei, Y Ishikawa, K Hara, ... ACS omega 3 (9), 12284-12294, 2018 | 14 | 2018 |