Expression of the Multiple Sclerosis-Associated MHC Class II Allele HLA-DRB1*1501 Is Regulated by Vitamin D SV Ramagopalan, NJ Maugeri, L Handunnetthi, MR Lincoln, SM Orton, ... PLoS genetics 5 (2), e1000369, 2009 | 694 | 2009 |
Identification of genetic factors that modify clinical onset of Huntington’s disease JM Lee, VC Wheeler, MJ Chao, JPG Vonsattel, RM Pinto, D Lucente, ... Cell 162 (3), 516-526, 2015 | 448 | 2015 |
CAG repeat not polyglutamine length determines timing of Huntington’s disease onset JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ... Cell 178 (4), 887-900. e14, 2019 | 319 | 2019 |
Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9 JW Shin, KH Kim, MJ Chao, RS Atwal, T Gillis, ME MacDonald, JF Gusella, ... Human molecular genetics 25 (20), 4566-4576, 2016 | 316 | 2016 |
Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis SM Orton, AP Morris, BM Herrera, SV Ramagopalan, MR Lincoln, ... The American journal of clinical nutrition 88 (2), 441-447, 2008 | 291 | 2008 |
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia TCW Julia, L Qian, NH Pipalia, MJ Chao, SA Liang, Y Shi, BR Jain, ... Cell 185 (13), 2213-2233. e25, 2022 | 197 | 2022 |
Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility MR Lincoln, SV Ramagopalan, MJ Chao, BM Herrera, GC DeLuca, ... Proceedings of the National Academy of Sciences 106 (18), 7542-7547, 2009 | 197 | 2009 |
The inheritance of resistance alleles in multiple sclerosis SV Ramagopalan, AP Morris, DA Dyment, BM Herrera, GC DeLuca, ... PLoS genetics 3 (9), e150, 2007 | 195 | 2007 |
An extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus GC DeLuca, SV Ramagopalan, BM Herrera, DA Dyment, MR Lincoln, ... Proceedings of the National Academy of Sciences 104 (52), 20896-20901, 2007 | 161 | 2007 |
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control HP Gideon, TK Hughes, CN Tzouanas, MH Wadsworth, AA Tu, ... Immunity 55 (5), 827-846. e10, 2022 | 135 | 2022 |
Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex MJ Chao, SV Ramagopalan, BM Herrera, MR Lincoln, DA Dyment, ... Human Molecular Genetics 18 (2), 261-266, 2009 | 121 | 2009 |
HLA class I alleles tag HLA-DRB1* 1501 haplotypes for differential risk in multiple sclerosis susceptibility MJ Chao, MCNM Barnardo, MR Lincoln, SV Ramagopalan, BM Herrera, ... Proceedings of the National Academy of Sciences 105 (35), 13069-13074, 2008 | 110 | 2008 |
A modifier of Huntington's disease onset at the MLH1 locus JM Lee, MJ Chao, D Harold, K Abu Elneel, T Gillis, P Holmans, L Jones, ... Human molecular genetics 26 (19), 3859-3867, 2017 | 105 | 2017 |
Parent-of-origin effects in MS: observations from avuncular pairs BM Herrera, SV Ramagopalan, MR Lincoln, SM Orton, MJ Chao, ... Neurology 71 (11), 799-803, 2008 | 99 | 2008 |
Sex-specific genetic predictors of Alzheimer’s disease biomarkers Y Deming, L Dumitrescu, LL Barnes, M Thambisetty, B Kunkle, KA Gifford, ... Acta neuropathologica 136, 857-872, 2018 | 97 | 2018 |
Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians SM Orton, SV Ramagopalan, AE Para, MR Lincoln, L Handunnetthi, ... Journal of the neurological sciences 305 (1-2), 116-120, 2011 | 89 | 2011 |
Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism M Kapoor, JC Wang, SP Farris, Y Liu, J McClintick, I Gupta, JL Meyers, ... Translational psychiatry 9 (1), 89, 2019 | 87 | 2019 |
MHC transmission: insights into gender bias in MS susceptibility MJ Chao, SV Ramagopalan, BM Herrera, SM Orton, L Handunnetthi, ... Neurology 76 (3), 242-246, 2011 | 80 | 2011 |
Sex differences in the genetic predictors of Alzheimer’s pathology L Dumitrescu, LL Barnes, M Thambisetty, G Beecham, B Kunkle, WS Bush, ... Brain 142 (9), 2581-2589, 2019 | 77 | 2019 |
Exome sequencing identifies a novel multiple sclerosis susceptibility variant in the TYK2 gene DA Dyment, MZ Cader, MJ Chao, MR Lincoln, KM Morrison, G Disanto, ... Neurology 79 (5), 406-411, 2012 | 67 | 2012 |