The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ... Nature 486 (7403), 346-352, 2012 | 5990 | 2012 |
Spatial coupling of mTOR and autophagy augments secretory phenotypes M Narita, ARJ Young, S Arakawa, SA Samarajiwa, T Nakashima, ... Science 332 (6032), 966-70, 2011 | 580 | 2011 |
Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape BN Bidwell, CY Slaney, NP Withana, S Forster, Y Cao, S Loi, D Andrews, ... Nature Medicine, 2012 | 520 | 2012 |
Type I interferon receptors: biochemistry and biological functions NA De Weerd, SA Samarajiwa, PJ Hertzog Journal of Biological Chemistry 282 (28), 20053-20057, 2007 | 519 | 2007 |
Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation T Chandra, K Kirschner, JY Thuret, BD Pope, T Ryba, S Newman, ... Molecular Cell, 2012 | 306 | 2012 |
INTERFEROME: the database of interferon regulated genes SA Samarajiwa, S Forster, K Auchettl, PJ Hertzog Nucleic acids research 37 (suppl_1), D852-D857, 2009 | 291 | 2009 |
A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data NL Barbosa-Morais, MJ Dunning, SA Samarajiwa, JFJ Darot, ME Ritchie, ... Nucleic acids research 38 (3), e17-e17, 2010 | 285 | 2010 |
Systems biology of interferon responses P Hertzog, S Forster, S Samarajiwa Journal of Interferon & Cytokine Research 31 (1), 5-11, 2011 | 164 | 2011 |
ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium DG Holland, A Burleigh, A Git, MA Goldgraben, PA Perez‐Mancera, ... EMBO molecular medicine 3 (3), 167-180, 2011 | 142 | 2011 |
HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production AN Harman, J Lai, S Turville, S Samarajiwa, L Gray, V Marsden, ... Blood, The Journal of the American Society of Hematology 118 (2), 298-308, 2011 | 129 | 2011 |
Fumarate induces vesicular release of mtDNA to drive innate immunity V Zecchini, V Paupe, I Herranz-Montoya, J Janssen, IMN Wortel, JL Morris, ... Nature 615 (7952), 499-506, 2023 | 98 | 2023 |
A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma SE Syafruddin, P Rodrigues, E Vojtasova, SA Patel, MN Zaini, J Burge, ... Nature communications 10 (1), 1152, 2019 | 72 | 2019 |
Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity. MCP Turrell FK, Kerr EM, Gao M, Thorpe H, Doherty GJ, Cridge J, Shorthouse D ... Genes Dev., 2017 | 64 | 2017 |
NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence AJ Parry, M Hoare, D Bihary, R Hänsel-Hertsch, S Smith, K Tomimatsu, ... Nature communications 9 (1), 1-15, 2018 | 62 | 2018 |
Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53. Kirschner K, Samarajiwa SA, Cairns JM, Menon S, Pérez-Mancera PA, Tomimatsu ... PLoS Genet. 11 (3), 2015 | 62 | 2015 |
Sequential Inverse Dysregulation of the RNA Helicases DDX3X and DDX3Y Facilitates MYC-Driven Lymphomagenesis C Gong, J Krupka, J Gao, NF Grigoropoulos, M Screen, Z Usheva, ... | 54 | 2020 |
A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer. KVN Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde ... Mol Oncol., 2015 | 53 | 2015 |
Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence Ioana Olan, Aled J. Parry, Stefan Schoenfelder, Masako Narita, Yoko Ito ... Nature Communications 11 (6049), 2020 | 52 | 2020 |
Transcription-driven cohesin repositioning rewires chromatin loops in cellular senescence I Olan, AJ Parry, S Schoenfelder, M Narita, Y Ito, ASL Chan, G Slater, ... bioRxiv, 2019 | 52* | 2019 |
NF-κB–dependent lymphoid enhancer co-option promotes renal carcinoma metastasis P Rodrigues, SA Patel, L Harewood, I Olan, E Vojtasova, SE Syafruddin, ... Cancer discovery 8 (7), 850-865, 2018 | 47 | 2018 |