Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease RJ Johnson, MS Segal, Y Sautin, T Nakagawa, DI Feig, DH Kang, ... The American journal of clinical nutrition 86 (4), 899-906, 2007 | 1424 | 2007 |
Fructose and sugar: A major mediator of non-alcoholic fatty liver disease T Jensen, MF Abdelmalek, S Sullivan, KJ Nadeau, M Green, C Roncal, ... Journal of hepatology 68 (5), 1063-1075, 2018 | 903 | 2018 |
Sugar, uric acid, and the etiology of diabetes and obesity RJ Johnson, T Nakagawa, LG Sanchez-Lozada, M Shafiu, S Sundaram, ... Diabetes 62 (10), 3307-3315, 2013 | 875 | 2013 |
Uric acid and chronic kidney disease: which is chasing which? RJ Johnson, T Nakagawa, D Jalal, LG Sánchez-Lozada, DH Kang, E Ritz Nephrology Dialysis Transplantation 28 (9), 2221-2228, 2013 | 734 | 2013 |
Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats LG Sanchez-Lozada, E Tapia, J Santamaria, C Avila-Casado, V Soto, ... Kidney international 67 (1), 237-247, 2005 | 733 | 2005 |
Hypothesis: could excessive fructose intake and uric acid cause type 2 diabetes? RJ Johnson, SE Perez-Pozo, YY Sautin, J Manitius, LG Sanchez-Lozada, ... Endocrine reviews 30 (1), 96-116, 2009 | 718 | 2009 |
Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and-independent fatty liver MA Lanaspa, LG Sanchez-Lozada, YJ Choi, C Cicerchi, M Kanbay, ... Journal of Biological Chemistry 287 (48), 40732-40744, 2012 | 709 | 2012 |
Oxidative stress with an activation of the renin–angiotensin system in human vascular endothelial cells as a novel mechanism of uric acid-induced endothelial dysfunction MA Yu, LG Sánchez-Lozada, RJ Johnson, DH Kang Journal of hypertension 28 (6), 1234-1242, 2010 | 652 | 2010 |
Hyperuricemia, acute and chronic kidney disease, hypertension, and cardiovascular disease: report of a scientific workshop organized by the National Kidney Foundation RJ Johnson, GL Bakris, C Borghi, MB Chonchol, D Feldman, MA Lanaspa, ... American Journal of Kidney Diseases 71 (6), 851-865, 2018 | 501 | 2018 |
Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats LG Sánchez-Lozada, E Tapia, A Jiménez, P Bautista, M Cristóbal, ... American journal of physiology-renal physiology 292 (1), F423-F429, 2007 | 483 | 2007 |
Mild hyperuricemia induces glomerular hypertension in normal rats LG Sánchez-Lozada, E Tapia, C Avila-Casado, V Soto, M Franco, ... American Journal of Physiology-Renal Physiology 283 (5), F1105-F1110, 2002 | 431 | 2002 |
Hyperuricemia causes glomerular hypertrophy in the rat T Nakagawa, M Mazzali, DH Kang, J Kanellis, S Watanabe, ... American journal of nephrology 23 (1), 2-7, 2002 | 424 | 2002 |
Essential hypertension, progressive renal disease, and uric acid: a pathogenetic link? RJ Johnson, MS Segal, T Srinivas, A Ejaz, W Mu, C Roncal, ... Journal of the American Society of Nephrology 16 (7), 1909-1919, 2005 | 418 | 2005 |
Excessive fructose intake induces the features of metabolic syndrome in healthy adult men: role of uric acid in the hypertensive response SE Perez-Pozo, J Schold, T Nakagawa, LG Sánchez-Lozada, RJ Johnson, ... International journal of obesity 34 (3), 454-461, 2010 | 417 | 2010 |
Climate change and the emergent epidemic of CKD from heat stress in rural communities: the case for heat stress nephropathy J Glaser, J Lemery, B Rajagopalan, HF Diaz, R García-Trabanino, ... Clinical Journal of the American Society of Nephrology 11 (8), 1472-1483, 2016 | 414 | 2016 |
Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia LG Sánchez-Lozada, V Soto, E Tapia, C Avila-Casado, YY Sautin, ... American Journal of Physiology-Renal Physiology 295 (4), F1134-F1141, 2008 | 413 | 2008 |
High‐fat and high‐sucrose (western) diet induces steatohepatitis that is dependent on fructokinase T Ishimoto, MA Lanaspa, CJ Rivard, CA Roncal‐Jimenez, DJ Orlicky, ... Hepatology 58 (5), 1632-1643, 2013 | 362 | 2013 |
Uric acid-induced endothelial dysfunction is associated with mitochondrial alterations and decreased intracellular ATP concentrations LG Sánchez-Lozada, MA Lanaspa, M Cristóbal-García, F García-Arroyo, ... Nephron Experimental Nephrology 121 (3-4), e71-e78, 2013 | 349 | 2013 |
Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver MA Lanaspa, LG Sanchez-Lozada, C Cicerchi, N Li, CA Roncal-Jimenez, ... PloS one 7 (10), e47948, 2012 | 311 | 2012 |
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice T Ishimoto, MA Lanaspa, MPT Le, GE Garcia, CP Diggle, PS MacLean, ... Proceedings of the National Academy of Sciences 109 (11), 4320-4325, 2012 | 308 | 2012 |