Structural and immunological principles leading to chemically synthesized, multiantigenic, multistage, minimal subunit-based vaccine development ME Patarroyo, A Bermúdez, MA Patarroyo Chemical reviews 111 (5), 3459-3507, 2011 | 109 | 2011 |
Strategies for developing multi‐epitope, subunit‐based, chemically synthesized anti‐malarial vaccines ME Patarroyo, G Cifuentes, A Bermudez, MA Patarroyo Journal of cellular and molecular medicine 12 (5b), 1915-1935, 2008 | 50 | 2008 |
Shifting the polarity of some critical residues in malarial peptides' binding to host cells is a key factor in breaking conserved antigens' code of silence G Cifuentes, A Bermudez, R Rodriguez, MA Patarroyo, ME Patarroyo Medicinal Chemistry 4 (3), 278-292, 2008 | 38 | 2008 |
IMPIPS: The Immune Protection-Inducing Protein Structure Concept in the Search for Steric-Electron and Topochemical Principles for Complete Fully-Protective … ME Patarroyo, A Bermúdez, MP Alba, M Vanegas, A Moreno-Vranich, ... PLoS One 10 (4), e0123249, 2015 | 34 | 2015 |
Immunogenicity and protectivity of Plasmodium falciparum EBA-175 peptide and its analog is associated with α-helical region shortening and displacement A Bermúdez, G Cifuentes, F Guzmán, LM Salazar, ME Patarroyo Walter de Gruyter 384 (10-11), 1443-1450, 2003 | 31 | 2003 |
Shortening and modifying the 1513 MSP-1 peptide’s α-helical region induces protection against malaria F Espejo, A Bermúdez, E Torres, M Urquiza, R Rodrıguez, Y López, ... Biochemical and biophysical research communications 315 (2), 418-427, 2004 | 30 | 2004 |
Structural and immunological analysis of circumsporozoite protein peptides: a further step in the identification of potential components of a minimal subunit-based, chemically … A Bermúdez, M Vanegas, ME Patarroyo Vaccine 26 (52), 6908-6918, 2008 | 28 | 2008 |
3D analysis of the TCR/pMHCII complex formation in monkeys vaccinated with the first peptide inducing sterilizing immunity against human malaria MA Patarroyo, A Bermúdez, C López, G Yepes, ME Patarroyo Plos one 5 (3), e9771, 2010 | 27 | 2010 |
Gauche+ side-chain orientation as a key factor in the search for an immunogenic peptide mixture leading to a complete fully protective vaccine A Bermúdez, D Calderon, A Moreno-Vranich, H Almonacid, MA Patarroyo, ... Vaccine 32 (18), 2117-2126, 2014 | 26 | 2014 |
A single amino acid change in the Plasmodium falciparum RH5 (PfRH5) human RBC binding sequence modifies its structure and determines species-specific binding activity G Arévalo-Pinzón, H Curtidor, M Muñoz, MA Patarroyo, A Bermudez, ... Vaccine 30 (3), 637-646, 2012 | 24 | 2012 |
Synthetic vaccine update: applying lessons learned from recent SPf66 malarial vaccine physicochemical, structural and immunological characterization A Bermúdez, C Reyes, F Guzmán, M Vanegas, J Rosas, R Amador, ... Vaccine 25 (22), 4487-4501, 2007 | 24 | 2007 |
Sporozoite and liver stage antigen Plasmodium falciparum peptides bind specifically to human hepatocytes A Puentes, J Garcıa, R Vera, R López, J Suarez, L Rodrıguez, H Curtidor, ... Vaccine 22 (9-10), 1150-1156, 2004 | 24 | 2004 |
Phi (Φ) and psi (Ψ) angles involved in malarial peptide bonds determine sterile protective immunity ME Patarroyo, A Moreno-Vranich, A Bermúdez Biochemical and biophysical research communications 429 (1-2), 75-80, 2012 | 21 | 2012 |
The high immunogenicity induced by modified sporozoites’ malarial peptides depends on their phi (ϕ) and psi (ψ) angles ME Patarroyo, A Bermudez, MP Alba Biochemical and Biophysical Research Communications 429 (1-2), 81-86, 2012 | 21 | 2012 |
Studies of Plasmodium falciparum rhoptry-associated membrane antigen (RAMA) protein peptides specifically binding to human RBC CG Pinzón, H Curtidor, A Bermúdez, M Forero, M Vanegas, J Rodríguez, ... Vaccine 26 (6), 853-862, 2008 | 20 | 2008 |
Peptides of the liver stage antigen-1 (LSA-1) of Plasmodium falciparum bind to human hepatocytes JE Garcı́a, A Puentes, R López, R Vera, J Suárez, L Rodrı́guez, H Curtidor, ... Peptides 24 (5), 647-657, 2003 | 17 | 2003 |
Towards the development of a fully protective Plasmodium falciparum antimalarial vaccine ME Patarroyo, A Bermudez, A Moreno-Vranich Expert Review of Vaccines 11 (9), 1057-1070, 2012 | 16 | 2012 |
Conserved binding regions provide the clue for peptide-based vaccine development: a chemical perspective H Curtidor, C Reyes, A Bermúdez, M Vanegas, Y Varela, ME Patarroyo Molecules 22 (12), 2199, 2017 | 15 | 2017 |
Functionally Relevant Proteins in Plasmodium Falciparum Host Cell Invasion ME Patarroyo, MP Alba, R Rojas-Luna, A Bermudez, J Aza-Conde Immunotherapy 9 (2), 131-155, 2017 | 15 | 2017 |
Changing ABRA protein peptide to fit into the HLA-DRβ1* 0301 molecule renders it protection-inducing LM Salazar, MP Alba, H Curtidor, A Bermúdez, LE Vargas, ZJ Rivera, ... Biochemical and biophysical research communications 322 (1), 119-125, 2004 | 15 | 2004 |