APOBEC3G DNA deaminase acts processively 3′→ 5′ on single-stranded DNA L Chelico, P Pham, P Calabrese, MF Goodman Nature structural & molecular biology 13 (5), 392-399, 2006 | 347 | 2006 |
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications LG Holden, C Prochnow, YP Chang, R Bransteitter, L Chelico, U Sen, ... Nature 456 (7218), 121-124, 2008 | 296 | 2008 |
The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis GJ Starrett, EM Luengas, JL McCann, D Ebrahimi, NA Temiz, RP Love, ... Nature communications 7 (1), 12918, 2016 | 167 | 2016 |
Suppression of APOBEC3-mediated restriction of HIV-1 by Vif Y Feng, TT Baig, RP Love, L Chelico Frontiers in microbiology 5, 450, 2014 | 137 | 2014 |
Structural Model for Deoxycytidine Deamination Mechanisms of the HIV-1 Inactivation Enzyme APOBEC3G*♦ L Chelico, C Prochnow, DA Erie, XS Chen, MF Goodman Journal of Biological Chemistry 285 (21), 16195-16205, 2010 | 134 | 2010 |
A model for oligomeric regulation of APOBEC3G cytosine deaminase-dependent restriction of HIV L Chelico, EJ Sacho, DA Erie, MF Goodman Journal of Biological Chemistry 283 (20), 13780-13791, 2008 | 120 | 2008 |
Biochemical analysis of hypermutation by the deoxycytidine deaminase APOBEC3A RP Love, H Xu, L Chelico Journal of Biological Chemistry 287 (36), 30812-30822, 2012 | 88 | 2012 |
Different mutagenic potential of HIV-1 restriction factors APOBEC3G and APOBEC3F is determined by distinct single-stranded DNA scanning mechanisms A Ara, RP Love, L Chelico PLoS pathogens 10 (3), e1004024, 2014 | 71 | 2014 |
Single-stranded DNA Scanning and Deamination by APOBEC3G Cytidine Deaminase at Single Molecule Resolution*♦ G Senavirathne, M Jaszczur, PA Auerbach, TG Upton, L Chelico, ... Journal of Biological Chemistry 287 (19), 15826-15835, 2012 | 69 | 2012 |
Intensity of deoxycytidine deamination of HIV-1 proviral DNA by the retroviral restriction factor APOBEC3G is mediated by the noncatalytic domain Y Feng, L Chelico Journal of Biological Chemistry 286 (13), 11415-11426, 2011 | 69 | 2011 |
A single nucleotide polymorphism in human APOBEC3C enhances restriction of lentiviruses CJ Wittkopp, MB Adolph, LI Wu, L Chelico, M Emerman PLoS pathogens 12 (10), e1005865, 2016 | 66 | 2016 |
Dissecting APOBEC3G substrate specificity by nucleoside analog interference JW Rausch, L Chelico, MF Goodman, SFJ Le Grice Journal of Biological Chemistry 284 (11), 7047-7058, 2009 | 61 | 2009 |
Stochastic properties of processive cytidine DNA deaminases AID and APOBEC3G L Chelico, P Pham, MF Goodman Philosophical Transactions of the Royal Society B: Biological Sciences 364 …, 2009 | 61 | 2009 |
Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B MB Adolph, RP Love, Y Feng, L Chelico Nucleic acids research 45 (20), 11925-11940, 2017 | 56 | 2017 |
Retroviral restriction factor APOBEC3G delays the initiation of DNA synthesis by HIV-1 reverse transcriptase MB Adolph, J Webb, L Chelico PloS one 8 (5), e64196, 2013 | 54 | 2013 |
Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure YZ McDaniel, D Wang, RP Love, MB Adolph, N Mohammadzadeh, ... Nucleic acids research 48 (3), 1353-1371, 2020 | 50 | 2020 |
Cytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization MB Adolph, A Ara, Y Feng, CJ Wittkopp, M Emerman, JS Fraser, L Chelico Nucleic acids research 45 (6), 3378-3394, 2017 | 50 | 2017 |
Mechanism of enhanced HIV restriction by virion coencapsidated cytidine deaminases APOBEC3F and APOBEC3G A Ara, RP Love, TB Follack, KA Ahmed, MB Adolph, L Chelico Journal of virology 91 (3), 10.1128/jvi. 02230-16, 2017 | 48 | 2017 |
Natural polymorphisms and oligomerization of human APOBEC3H contribute to single-stranded DNA scanning ability Y Feng, RP Love, A Ara, TT Baig, MB Adolph, L Chelico Journal of Biological Chemistry 290 (45), 27188-27203, 2015 | 45 | 2015 |
Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G H Yang, F Ito, AD Wolfe, S Li, N Mohammadzadeh, RP Love, M Yan, ... Nature communications 11 (1), 632, 2020 | 42 | 2020 |