| Amino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids KM Knights, MJ Sykes, JO Miners Expert opinion on drug metabolism & toxicology 3 (2), 159-168, 2007 | 112 | 2007 |
| Prediction of metabolism by cytochrome P450 2C9: alignment and docking studies of a validated database of substrates MJ Sykes, RA McKinnon, JO Miners Journal of medicinal chemistry 51 (4), 780-791, 2008 | 91 | 2008 |
| Discovery of 5‐(2‐(Phenylamino)pyrimidin‐4‐yl)thiazol‐2(3H)‐one Derivatives as Potent Mnk2 Inhibitors: Synthesis, SAR Analysis and Biological Evaluation S Diab, T Teo, M Kumarasiri, P Li, M Yu, F Lam, SKC Basnet, MJ Sykes, ... ChemMedChem 9 (5), 962-972, 2014 | 86 | 2014 |
| DNA binding of an organic dppz-based intercalator T Phillips, I Haq, AJHM Meijer, H Adams, I Soutar, L Swanson, MJ Sykes, ... Biochemistry 43 (43), 13657-13665, 2004 | 82 | 2004 |
| The Gaussian Generalized Born model: application to small molecules JA Grant, BT Pickup, MJ Sykes, CA Kitchen, A Nicholls Physical Chemistry Chemical Physics 9 (35), 4913-4922, 2007 | 74 | 2007 |
| Targeting Pim kinases for cancer treatment: opportunities and challenges BT Le, M Kumarasiri, JRJ Adams, M Yu, R Milne, MJ Sykes, S Wang Future medicinal chemistry 7 (1), 35-53, 2015 | 55 | 2015 |
| Pharmacologic co-inhibition of Mnks and mTORC1 synergistically suppresses proliferation and perturbs cell cycle progression in blast crisis-chronic myeloid leukemia cells T Teo, M Yu, Y Yang, T Gillam, F Lam, MJ Sykes, S Wang Cancer letters 357 (2), 612-623, 2015 | 51 | 2015 |
| A systematic review and meta-analysis considering the risk for congenital heart defects of antidepressant classes and individual antidepressants C De Vries, S Gadzhanova, MJ Sykes, M Ward, E Roughead Drug Safety 44, 291-312, 2021 | 45 | 2021 |
| Pharmacologic inhibition of MNKs in acute myeloid leukemia T Teo, F Lam, M Yu, Y Yang, SKC Basnet, H Albrecht, MJ Sykes, S Wang Molecular pharmacology 88 (2), 380-389, 2015 | 43 | 2015 |
| Molecular modeling approaches for the prediction of the nonspecific binding of drugs to hepatic microsomes MJ Sykes, MJ Sorich, JO Miners Journal of chemical information and modeling 46 (6), 2661-2673, 2006 | 41 | 2006 |
| Identification of a Novel Oligomerization Disrupting Mutation in CRYΑA Associated with Congenital Cataract in a South Australian Family KJ Laurie, A Dave, T Straga, E Souzeau, T Chataway, MJ Sykes, T Casey, ... Human mutation 34 (3), 435-438, 2013 | 36 | 2013 |
| An integrated approach for discovery of highly potent and selective Mnk inhibitors: Screening, synthesis and SAR analysis T Teo, Y Yang, M Yu, SKC Basnet, T Gillam, J Hou, RM Schmid, ... European journal of medicinal chemistry 103, 539-550, 2015 | 34 | 2015 |
| A simple formula for dielectric polarisation energies: The Sheffield Solvation Model JA Grant, BT Pickup, MJ Sykes, CA Kitchen, A Nicholls Chemical physics letters 441 (1-3), 163-166, 2007 | 34 | 2007 |
| Synthesis and Extended Activity of Triazole‐Containing Macrocyclic Protease Inhibitors AD Pehere, M Pietsch, M Gütschow, PM Neilsen, DS Pedersen, S Nguyen, ... Chemistry–A European Journal 19 (24), 7975-7981, 2013 | 31 | 2013 |
| Biological effect of LOXL1 coding variants associated with pseudoexfoliation syndrome S Sharma, S Martin, MJ Sykes, A Dave, AW Hewitt, KP Burdon, M Ronci, ... Experimental eye research 146, 212-223, 2016 | 28 | 2016 |
| Quantum-mechanical QSAR/QSPR descriptors from momentum-space wave functions EF McCoy, MJ Sykes Journal of chemical information and computer sciences 43 (2), 545-553, 2003 | 28 | 2003 |
| Design and structural optimization of novel 2H-benzo [h] chromene derivatives that target AcrB and reverse bacterial multidrug resistance Y Wang, R Alenazy, X Gu, SW Polyak, P Zhang, MJ Sykes, N Zhang, ... European Journal of Medicinal Chemistry 213, 113049, 2021 | 27 | 2021 |
| Kinetics membrane disruption due to drug interactions of chlorpromazine hydrochloride MR Nussio, MJ Sykes, JO Miners, JG Shapter Langmuir 25 (2), 1086-1090, 2009 | 27 | 2009 |
| Characterisation of the binding of cationic amphiphilic drugs to phospholipid bilayers using surface plasmon resonance MR Nussio, MJ Sykes, JO Miners, JG Shapter ChemMedChem: Chemistry Enabling Drug Discovery 2 (3), 366-373, 2007 | 26 | 2007 |
| Discovery of CDK5 inhibitors through structure-guided approach NZ Khair, JL Lenjisa, S Tadesse, M Kumarasiri, SKC Basnet, ... ACS Medicinal Chemistry Letters 10 (5), 786-791, 2019 | 24 | 2019 |
John O. MinersMatthew Flinders Distinguished Professor在 flinders.edu.au 的电子邮件经过验证
