Anticancer activity of structurally related ruthenium (II) cyclopentadienyl complexes L Côrte-Real, F Mendes, J Coimbra, TS Morais, AI Tomaz, A Valente, ... JBIC Journal of Biological Inorganic Chemistry 19, 853-867, 2014 | 76 | 2014 |
New water-soluble ruthenium (II) cytotoxic complex: Biological activity and cellular distribution TS Morais, FC Santos, TF Jorge, L Côrte-Real, PJA Madeira, F Marques, ... Journal of Inorganic Biochemistry 130, 1-14, 2014 | 69 | 2014 |
Biological activity and cellular uptake of [Ru (η5-C5H5)(PPh3)(Me2bpy)][CF3SO3] complex TS Morais, F Santos, L Côrte-Real, F Marques, MP Robalo, PJA Madeira, ... Journal of Inorganic Biochemistry 122, 8-17, 2013 | 58 | 2013 |
Cellular uptake mechanisms of an antitumor ruthenium compound: The endosomal/lysosomal system as a target for anticancer metal-based drugs L Côrte-Real, AP Matos, I Alho, TS Morais, AI Tomaz, MH Garcia, I Santos, ... Microscopy and Microanalysis 19 (5), 1122-1130, 2013 | 51 | 2013 |
Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand L Côrte-Real, B Karas, P Gírio, A Moreno, F Avecilla, F Marques, ... European journal of medicinal chemistry 163, 853-863, 2019 | 49 | 2019 |
The key role of coligands in novel ruthenium (II)-cyclopentadienyl bipyridine derivatives: Ranging from non-cytotoxic to highly cytotoxic compounds L Côrte-Real, MP Robalo, F Marques, G Nogueira, F Avecilla, TJL Silva, ... Journal of Inorganic Biochemistry 150, 148-159, 2015 | 45 | 2015 |
Methyl-cyclopentadienyl ruthenium compounds with 2, 2′-bipyridine derivatives display strong anticancer activity and multidrug resistance potential L Côrte-Real, RG Teixeira, P Gírio, E Comsa, A Moreno, R Nasr, ... Inorganic Chemistry 57 (8), 4629-4639, 2018 | 42 | 2018 |
Ruthenium–Cyclopentadienyl Bipyridine–Biotin Based Compounds: Synthesis and Biological Effect L Côrte-Real, B Karas, AR Brás, A Pilon, F Avecilla, F Marques, A Preto, ... Inorganic chemistry 58 (14), 9135-9149, 2019 | 37 | 2019 |
Exploring the effect of the ligand design on the interactions between [Ru (η5-C5H5)(PPh3)(N, O)][CF3SO3] complexes and human serum albumin TS Morais, FC Santos, L Corte-Real, MH Garcia Journal of Inorganic Biochemistry 129, 94-101, 2013 | 29 | 2013 |
A new family of iron (II)-cyclopentadienyl compounds shows strong activity against colorectal and triple negative breast cancer cells A Pilon, AR Brás, L Côrte-Real, F Avecilla, PJ Costa, A Preto, MH Garcia, ... Molecules 25 (7), 1592, 2020 | 26 | 2020 |
Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells RG Teixeira, AR Brás, L Côrte-Real, R Tatikonda, A Sanches, MP Robalo, ... European Journal of Medicinal Chemistry 143, 503-514, 2018 | 26 | 2018 |
New iron (II) cyclopentadienyl derivative complexes: Synthesis and antitumor activity against human leukemia cancer cells A Valente, AM Santos, L Côrte-Real, MP Robalo, V Moreno, ... Journal of Organometallic Chemistry 756, 52-60, 2014 | 24 | 2014 |
Studies on the mechanism of action of antitumor bis (aminophenolate) ruthenium (III) complexes O Dömötör, RFM de Almeida, L Côrte-Real, CP Matos, F Marques, ... Journal of Inorganic Biochemistry 168, 27-37, 2017 | 23 | 2017 |
A novel screening method for transition metal‐based anticancer compounds using zebrafish embryo‐larval assay and inductively coupled plasma‐mass spectrometry analysis BF Karas, L Côrte‐Real, CL Doherty, A Valente, KR Cooper, BT Buckley Journal of applied toxicology 39 (8), 1173-1180, 2019 | 19 | 2019 |
Heteroleptic enantiopure Pd (ii)-complexes derived from halogen-substituted Schiff bases and 2-picolylamine: synthesis, experimental and computational characterization and … N Kordestani, HA Rudbari, I Correia, A Valente, L Côrte-Real, MK Islam, ... New Journal of Chemistry 45 (20), 9163-9180, 2021 | 16 | 2021 |
Anticancer activity and in vitro to in vivo mechanistic recapitulation of novel ruthenium-based metallodrugs in the zebrafish model BF Karas, JM Hotz, BM Gural, KR Terez, VL DiBona, L Côrte-Real, ... Toxicological Sciences 182 (1), 29-43, 2021 | 14 | 2021 |
Biotinylated Polymer-Ruthenium Conjugates: In Vitro and In Vivo Studies in a Triple-Negative Breast Cancer Model L Côrte-Real, AR Brás, A Pilon, N Mendes, AS Ribeiro, TD Martins, ... Pharmaceutics 14 (7), 1388, 2022 | 12 | 2022 |
Cu (II) and Zn (II) complexes of new 8-hydroxyquinoline Schiff bases: Investigating their structure, solution speciation, and anticancer potential L Côrte-Real, V Pósa, M Martins, R Colucas, NV May, X Fontrodona, ... Inorganic Chemistry 62 (29), 11466-11486, 2023 | 10 | 2023 |
New iron (III) anti-cancer aminobisphenolate/phenanthroline complexes: Enhancing their therapeutic potential using nanoliposomes CP Matos, M Albino, J Lopes, AS Viana, L Corte-Real, F Mendes, ... International Journal of Pharmaceutics 623, 121925, 2022 | 9 | 2022 |
Complexos de ruténio como potenciais agentes terapêuticos: estudos dos mecanismos de captação celular e modulação de enzimas metabólicas LSN Côrte-Real | 2 | 2012 |