| In Vivo Structure−Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors J Hao, JN Ho, JA Lewis, KA Karim, RN Daniels, PR Gentry, CR Hopkins, ... ACS chemical biology 5 (2), 245-253, 2010 | 438 | 2010 |
| Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells J Hao, MA Daleo, CK Murphy, PB Yu, JN Ho, J Hu, RT Peterson, ... PloS one 3 (8), e2904, 2008 | 283 | 2008 |
| Distinct signalling pathways regulate sprouting angiogenesis from the dorsal aorta and the axial vein DM Wiley, JD Kim, J Hao, CC Hong, VL Bautch, SW Jin Nature cell biology 13 (6), 686-692, 2011 | 243 | 2011 |
| Targeting signaling pathways in cancer stem cells for cancer treatment J Koury, L Zhong, J Hao Stem cells international 2017 (1), 2925869, 2017 | 152 | 2017 |
| Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/β-catenin signaling H Wang, J Hao, CC Hong ACS chemical biology 6 (2), 192-197, 2011 | 147 | 2011 |
| FOXC1 activates smoothened-independent hedgehog signaling in basal-like breast cancer B Han, Y Qu, Y Jin, Y Yu, N Deng, K Wawrowsky, X Zhang, N Li, S Bose, ... Cell reports 13 (5), 1046-1058, 2015 | 142 | 2015 |
| Current stem cell delivery methods for myocardial repair CC Sheng, L Zhou, J Hao BioMed research international 2013 (1), 547902, 2013 | 126 | 2013 |
| A thermostable variant of fructose bisphosphate aldolase constructed by directed evolution also shows increased stability in organic solvents J Hao, A Berry Protein Engineering Design and Selection 17 (9), 689-697, 2004 | 123 | 2004 |
| Recent development of Wnt signaling pathway inhibitors for cancer therapeutics J Harb, PJ Lin, J Hao Current oncology reports 21, 1-9, 2019 | 122 | 2019 |
| Development of anticancer agents targeting the Wnt/β-catenin signaling X Zhang, J Hao American journal of cancer research 5 (8), 2344, 2015 | 119 | 2015 |
| Selective small molecule targeting β-catenin function discovered by in vivo chemical genetic screen J Hao, A Ao, L Zhou, CK Murphy, AY Frist, JJ Keel, CA Thorne, K Kim, ... Cell reports 4 (5), 898-904, 2013 | 73 | 2013 |
| DMH1, a novel BMP small molecule inhibitor, increases cardiomyocyte progenitors and promotes cardiac differentiation in mouse embryonic stem cells A Ao, J Hao, CR Hopkins, CC Hong Public Library of Science 7 (7), e41627, 2012 | 66 | 2012 |
| DMH1, a small molecule inhibitor of BMP type i receptors, suppresses growth and invasion of lung cancer J Hao, R Lee, A Chang, J Fan, C Labib, C Parsa, R Orlando, B Andresen, ... PLoS One 9 (3), e90748, 2014 | 61 | 2014 |
| Rapid generation of sub-type, region-specific neurons and neural networks from human pluripotent stem cell-derived neurospheres AN Begum, C Guoynes, J Cho, J Hao, K Lutfy, Y Hong Stem cell research 15 (3), 731-741, 2015 | 52 | 2015 |
| An in vivo chemical genetic screen identifies phosphodiesterase 4 as a pharmacological target for hedgehog signaling inhibition CH Williams, JE Hempel, J Hao, AY Frist, MM Williams, JT Fleming, ... Cell reports 11 (1), 43-50, 2015 | 51 | 2015 |
| Treatment of Neurodegenerative Diseases with Bioactive Components of Tripterygium wilfordii J Li, J Hao The American journal of Chinese medicine 47 (04), 769-785, 2019 | 43 | 2019 |
| Polymodal allosteric regulation of Type 1 Serine/Threonine Kinase Receptors via a conserved electrostatic lock WM Botello-Smith, A Alsamarah, P Chatterjee, C Xie, JJ Lacroix, J Hao, ... PLoS Computational Biology 13 (8), e1005711, 2017 | 36 | 2017 |
| Regenerative chemical biology: current challenges and future potential A Ao, J Hao, CC Hong Chemistry & Biology 18 (4), 413-424, 2011 | 36 | 2011 |
| Triptonide effectively inhibits Wnt/β-catenin signaling via C-terminal transactivation domain of β-catenin J Chinison, JS Aguilar, A Avalos, Y Huang, Z Wang, DJ Cameron, J Hao Scientific reports 6 (1), 32779, 2016 | 35 | 2016 |
| Development of anticancer agents targeting the Hedgehog signaling X Zhang, Y Tian, Y Yang, J Hao Cellular and Molecular Life Sciences 74, 2773-2782, 2017 | 31 | 2017 |
