End‐to‐end continuous manufacturing of pharmaceuticals: integrated synthesis, purification, and final dosage formation S Mascia, PL Heider, H Zhang, R Lakerveld, B Benyahia, PI Barton, ... Angewandte Chemie 125 (47), 12585-12589, 2013 | 690 | 2013 |
Development of a multi-step synthesis and workup sequence for an integrated, continuous manufacturing process of a pharmaceutical PL Heider, SC Born, S Basak, B Benyahia, R Lakerveld, H Zhang, ... Organic Process Research & Development 18 (3), 402-409, 2014 | 186 | 2014 |
A plant-wide dynamic model of a continuous pharmaceutical process B Benyahia, R Lakerveld, PI Barton Industrial & engineering chemistry research 51 (47), 15393-15412, 2012 | 137 | 2012 |
Model‐based design of a plant‐wide control strategy for a continuous pharmaceutical plant R Lakerveld, B Benyahia, RD Braatz, PI Barton AIChE Journal 59 (10), 3671-3685, 2013 | 117 | 2013 |
The application of an automated control strategy for an integrated continuous pharmaceutical pilot plant R Lakerveld, B Benyahia, PL Heider, H Zhang, A Wolfe, CJ Testa, ... Organic Process Research & Development 19 (9), 1088-1100, 2015 | 103 | 2015 |
Application of continuous crystallization in an integrated continuous pharmaceutical pilot plant H Zhang, R Lakerveld, PL Heider, M Tao, M Su, CJ Testa, AN D’Antonio, ... Crystal growth & design 14 (5), 2148-2157, 2014 | 89 | 2014 |
Model predictive control of an integrated continuous pharmaceutical manufacturing pilot plant A Mesbah, JA Paulson, R Lakerveld, RD Braatz Organic Process Research & Development 21 (6), 844-854, 2017 | 76 | 2017 |
Process intensification for pharmaceutical crystallization J Wang, F Li, R Lakerveld Chemical Engineering and Processing-Process Intensification 127, 111-126, 2018 | 70 | 2018 |
Cocrystal engineering of itraconazole with suberic acid via rotary evaporation and spray drying J Weng, SN Wong, X Xu, B Xuan, C Wang, R Chen, CC Sun, R Lakerveld, ... Crystal Growth & Design 19 (5), 2736-2745, 2019 | 46 | 2019 |
Design, characterization and model validation of a LED-based photocatalytic reactor for gas phase applications F Khodadadian, MW De Boer, A Poursaeidesfahani, JR Van Ommen, ... Chemical Engineering Journal 333, 456-466, 2018 | 45 | 2018 |
CFD analysis of a Kenics static mixer with a low pressure drop under laminar flow conditions BW Nyande, K Mathew Thomas, R Lakerveld Industrial & Engineering Chemistry Research 60 (14), 5264-5277, 2021 | 43 | 2021 |
Membrane assisted crystallization using reverse osmosis: Influence of solubility characteristics on experimental application and energy saving potential R Lakerveld, J Kuhn, HJM Kramer, PJ Jansens, J Grievink Chemical Engineering Science 65 (9), 2689-2699, 2010 | 42 | 2010 |
A review on recent technologies for the manufacture of pulmonary drugs GD Hadiwinoto, PC Lip Kwok, R Lakerveld Therapeutic delivery 9 (1), 47-70, 2018 | 38 | 2018 |
Minimization of attrition and breakage in an airlift crystallizer A Soare, R Lakerveld, J Van Royen, G Zocchi, AI Stankiewicz, ... Industrial & engineering chemistry research 51 (33), 10895-10909, 2012 | 38 | 2012 |
An air-lift crystallizer can suppress secondary nucleation at a higher supersaturation compared to a stirred crystallizer R Lakerveld, JJH Van Krochten, HJM Kramer Crystal growth & design 14 (7), 3264-3275, 2014 | 37 | 2014 |
Microwave assisted direct nucleation control for batch crystallization: crystal size control with reduced batch time R Kacker, PM Salvador, GSJ Sturm, GD Stefanidis, R Lakerveld, ZK Nagy, ... Crystal Growth & Design 16 (1), 440-446, 2016 | 36 | 2016 |
Electric-field-assisted protein crystallization in continuous flow F Li, R Lakerveld Crystal Growth & Design 18 (5), 2964-2971, 2018 | 35 | 2018 |
Application of generic principles of process intensification to solution crystallization enabled by a task-based design approach R Lakerveld, HJM Kramer, AI Stankiewicz, J Grievink Chemical Engineering and Processing: Process Intensification 49 (9), 979-991, 2010 | 31 | 2010 |
Integrated solvent and process design for continuous crystallization and solvent recycling using PC‐SAFT J Wang, R Lakerveld AIChE Journal 64 (4), 1205-1216, 2018 | 30 | 2018 |
Characterization and dynamic optimization of membrane-assisted crystallization of adipic acid J Kuhn, R Lakerveld, HJM Kramer, J Grievink, PJ Jansens Industrial & Engineering Chemistry Research 48 (11), 5360-5369, 2009 | 30 | 2009 |