| Sphingolipids—the enigmatic lipid class: biochemistry, physiology, and pathophysiology AH Merrill Jr, EM Schmelz, DL Dillehay, S Spiegel, JA Shayman, ... Toxicology and applied pharmacology 142 (1), 208-225, 1997 | 835 | 1997 |
| Bcl-x and Bcl-2 inhibit TNF and Fas-induced apoptosis and activation of phospholipase A2 in breast carcinoma cells. M Jäättelä, M Benedict, M Tewari, JA Shayman, VM Dixit Oncogene 10 (12), 2297-2305, 1995 | 397 | 1995 |
| Increased alpha-adrenergic receptors in ischemic cat myocardium. A potential mediator of electrophysiological derangements. PB Corr, JA Shayman, JB Kramer, RJ Kipnis The Journal of Clinical Investigation 67 (4), 1232-1236, 1981 | 322 | 1981 |
| Improved inhibitors of glucosylceramide synthase L Lee, A Abe, JA Shayman Journal of Biological Chemistry 274 (21), 14662-14669, 1999 | 301 | 1999 |
| Globotriaosylceramide induces oxidative stress and up-regulates cell adhesion molecule expression in Fabry disease endothelial cells JS Shen, XL Meng, DF Moore, JM Quirk, JA Shayman, R Schiffmann, ... Molecular genetics and metabolism 95 (3), 163-168, 2008 | 288 | 2008 |
| (1S, 2R)-D-erythro-2-(N-Myristoylamino)-1-phenyl-1-propanol as an Inhibitor of Ceramidase (∗) A Bielawska, MS Greenberg, D Perry, S Jayadev, JA Shayman, C McKay, ... Journal of Biological Chemistry 271 (21), 12646-12654, 1996 | 253 | 1996 |
| Ganglioside-linked terminal sialic acid moieties on murine macrophages function as attachment receptors for murine noroviruses S Taube, JW Perry, K Yetming, SP Patel, H Auble, L Shu, HF Nawar, ... Journal of virology 83 (9), 4092-4101, 2009 | 244 | 2009 |
| Reduction of globotriaosylceramide in Fabry disease mice by substrate deprivation A Abe, S Gregory, L Lee, PD Killen, RO Brady, A Kulkarni, JA Shayman The Journal of clinical investigation 105 (11), 1563-1571, 2000 | 235 | 2000 |
| Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth. A Abe, NS Radin, JA Shayman, LL Wotring, RE Zipkin, R Sivakumar, ... Journal of lipid research 36 (3), 611-621, 1995 | 234 | 1995 |
| Improved inhibitors of glucosylceramide synthase A Abe, J Inokuchi, M Jimbo, H Shimeno, A Nagamatsu, JA Shayman, ... The Journal of Biochemistry 111 (2), 191-196, 1992 | 234 | 1992 |
| Metabolic effects of inhibiting glucosylceramide synthesis with PDMP and other substances. NS Radin Adv. Lipid Res. 26, 183-213, 1993 | 227 | 1993 |
| Adipocyte ceramides regulate subcutaneous adipose browning, inflammation, and metabolism B Chaurasia, VA Kaddai, GI Lancaster, DC Henstridge, S Sriram, ... Cell metabolism 24 (6), 820-834, 2016 | 226 | 2016 |
| Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models TA Natoli, LA Smith, KA Rogers, B Wang, S Komarnitsky, Y Budman, ... Nature medicine 16 (7), 788-792, 2010 | 207 | 2010 |
| A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher disease KA McEachern, J Fung, S Komarnitsky, CS Siegel, WL Chuang, E Hutto, ... Molecular genetics and metabolism 91 (3), 259-267, 2007 | 200 | 2007 |
| Cell Cycle Arrest Induced by an Inhibitor of Glucosylceramide Synthase: CORRELATION WITH CYCLIN-DEPENDENT KINASES (∗) SCS Rani, A Abe, Y Chang, N Rosenzweig, AR Saltiel, NS Radin, ... Journal of Biological Chemistry 270 (6), 2859-2867, 1995 | 191 | 1995 |
| Ceramides and glucosylceramides are independent antagonists of insulin signaling JA Chavez, MM Siddique, ST Wang, J Ching, JA Shayman, SA Summers Journal of Biological Chemistry 289 (2), 723-734, 2014 | 161 | 2014 |
| A role for glycosphingolipid accumulation in the renal hypertrophy of streptozotocin-induced diabetes mellitus. IZ Zador, GD Deshmukh, R Kunkel, K Johnson, NS Radin, JA Shayman The Journal of clinical investigation 91 (3), 797-803, 1993 | 158 | 1993 |
| Modulation of renal epithelial cell growth by glucosylceramide. Association with protein kinase C, sphingosine, and diacylglycerol. JA Shayman, GD Deshmukh, S Mahdiyoun, TP Thomas, D Wu, ... Journal of Biological Chemistry 266 (34), 22968-22974, 1991 | 158 | 1991 |
| Regulation of polymorphonuclear leukocyte phagocytosis by myosin light chain kinase after activation of mitogen-activated protein kinase PJ Mansfield, JA Shayman, LA Boxer Blood, The Journal of the American Society of Hematology 95 (7), 2407-2412, 2000 | 156 | 2000 |
| Drug induced phospholipidosis: an acquired lysosomal storage disorder JA Shayman, A Abe Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013 | 154 | 2013 |
