Advances in Fmoc solid‐phase peptide synthesis R Behrendt, P White, J Offer Journal of Peptide Science 22 (1), 4-27, 2016 | 782 | 2016 |
Exploiting the defensive sugars of HIV-1 for drug and vaccine design CN Scanlan, J Offer, N Zitzmann, RA Dwek Nature 446 (7139), 1038-1045, 2007 | 358 | 2007 |
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity SS Ng, KL Kavanagh, MA McDonough, D Butler, ES Pilka, BMR Lienard, ... Nature 448 (7149), 87-91, 2007 | 350 | 2007 |
Extending synthetic access to proteins with a removable acyl transfer auxiliary J Offer, CNC Boddy, PE Dawson Journal of the American Chemical Society 124 (17), 4642-4646, 2002 | 330 | 2002 |
Jarid2 methylation via the PRC2 complex regulates H3K27me3 deposition during cell differentiation S Sanulli, N Justin, A Teissandier, K Ancelin, M Portoso, M Caron, ... Molecular cell 57 (5), 769-783, 2015 | 305 | 2015 |
Nα-2-Mercaptobenzylamine-Assisted Chemical Ligation J Offer, PE Dawson Organic Letters 2 (1), 23-26, 2000 | 141 | 2000 |
An o-nitrobenzyl scaffold for peptide ligation: synthesis and applications C Marinzi, J Offer, R Longhi, PE Dawson Bioorganic & medicinal chemistry 12 (10), 2749-2757, 2004 | 121 | 2004 |
Native chemical ligation with Nα acyl transfer auxiliaries J Offer biopolymers Peptide Science 94 (4), 530-541, 2010 | 93 | 2010 |
A new scaffold for amide ligation C Marinzi, SJ Bark, J Offer, PE Dawson Bioorganic & medicinal chemistry 9 (9), 2323-2328, 2001 | 85 | 2001 |
Hypoxic Regulation of Hand1 Controls the Fetal-Neonatal Switch in Cardiac Metabolism RA Breckenridge, I Piotrowska, KE Ng, TJ Ragan, JA West, S Kotecha, ... PLoS Biology 11 (9), e1001666, 2013 | 78 | 2013 |
On-resin solid-phase synthesis of asparagine N-linked glycopeptides: Use of N-(2-acetoxy-4-methoxybenzyl)(AcHmb) aspartyl amide-bond protection to prevent unwanted aspartimide … J Offer, M Quibell, T Johnson Journal of the Chemical Society, Perkin Transactions 1, 175-182, 1996 | 75 | 1996 |
In situ thioester formation for protein ligation using α-methylcysteine F Burlina, G Papageorgiou, C Morris, PD White, J Offer Chemical Science 5 (2), 766-770, 2014 | 64 | 2014 |
HF‐free Boc synthesis of peptide thioesters for ligation and cyclization R Raz, F Burlina, M Ismail, J Downward, J Li, SJ Smerdon, M Quibell, ... Angewandte Chemie 128 (42), 13368-13373, 2016 | 42 | 2016 |
A backbone amide protecting group for overcoming difficult sequences and suppressing aspartimide formation ABM Abdel‐Aal, G Papageorgiou, R Raz, M Quibell, F Burlina, J Offer Journal of Peptide Science 22 (5), 360-367, 2016 | 42 | 2016 |
Application of reversible amide-bond protection to suppress peptide segment epimerisation J Offer, T Johnson, M Quibell Tetrahedron letters 38 (52), 9047-9050, 1997 | 33 | 1997 |
Head to tail cyclisation of cell-penetrating peptides: impact on GAG-dependent internalisation and direct translocation M Amoura, F Illien, A Joliot, K Guitot, J Offer, S Sagan, F Burlina Chemical Communications 55 (31), 4566-4569, 2019 | 29 | 2019 |
Automated synthesis of backbone protected peptides ABM Abdel-Aal, G Papageorgiou, M Quibell, J Offer Chemical Communications 50 (61), 8316-8319, 2014 | 29 | 2014 |
Cholesterol seco-sterol-induced aggregation of methylated amyloid-beta peptides--insights into aldehyde-initiated fibrillization of amyloid-beta JC Scheinost, H Wang, GE Boldt, J Offer, P Wentworth Jr Angew Chem Int Ed Engl 47 (21), 3919-3922, 2008 | 28 | 2008 |
Simplifying native chemical ligation with an N-acylsulfonamide linker F Burlina, C Morris, R Behrendt, P White, J Offer Chemical Communications 48 (20), 2579-2581, 2012 | 26 | 2012 |
The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein T Whitfield, AJ Miles, JC Scheinost, J Offer, P Wentworth Jr, RA Dwek, ... Molecular Membrane Biology 28 (5), 254-264, 2011 | 24 | 2011 |