Structure-based maximal affinity model predicts small-molecule druggability AC Cheng, RG Coleman, KT Smyth, Q Cao, P Soulard, DR Caffrey, ... Nature biotechnology 25 (1), 71-75, 2007 | 779 | 2007 |
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ... Carcinogenesis 36 (Suppl_1), S254-S296, 2015 | 350 | 2015 |
Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis? RB Robey, J Weisz, NB Kuemmerle, AC Salzberg, A Berg, DG Brown, ... Carcinogenesis 36 (Suppl_1), S203-S231, 2015 | 124 | 2015 |
Regulation of UDP-glucuronosyltransferase 1A1 expression and activity by microRNA 491-3p DF Dluzen, D Sun, AC Salzberg, N Jones, RT Bushey, GP Robertson, ... Journal of Pharmacology and Experimental Therapeutics 348 (3), 465-477, 2014 | 90 | 2014 |
MiR-365 regulates lung cancer and developmental gene thyroid transcription factor 1 J Qi, SJ Rice, AC Salzberg, EA Runkle, J Liao, DS Zander, D Mu Cell cycle 11 (1), 177-186, 2012 | 86 | 2012 |
Stage and gene specific signatures defined by histones H3K4me2 and H3K27me3 accompany mammalian retina maturation in vivo EY Popova, X Xu, AT DeWan, AC Salzberg, A Berg, J Hoh, SS Zhang, ... Public Library of Science 7 (10), e46867, 2012 | 57 | 2012 |
LSD1-mediated demethylation of H3K4me2 is required for the transition from late progenitor to differentiated mouse rod photoreceptor EY Popova, C Pinzon-Guzman, AC Salzberg, SSM Zhang, CJ Barnstable Molecular neurobiology 53, 4563-4581, 2016 | 43 | 2016 |
Structure-based identification of small molecule binding sites using a free energy model RG Coleman, AC Salzberg, AC Cheng Journal of chemical information and modeling 46 (6), 2631-2637, 2006 | 42 | 2006 |
Kcnn2 blockade reverses learning deficits in a mouse model of fetal alcohol spectrum disorders S Mohammad, SJ Page, L Wang, S Ishii, P Li, T Sasaki, A Basha, ... Nature Neuroscience 23 (4), 533-543, 2020 | 37 | 2020 |
Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability AC Salzberg, A Harris-Becker, EY Popova, N Keasey, TP Loughran, ... PloS one 12 (3), e0173723, 2017 | 37 | 2017 |
Genetic and environmental influences on plasma vitamin D binding protein concentrations RT Wilson, JD Bortner Jr, A Roff, A Das, EJ Battaglioli, JP Richie Jr, ... Translational Research 165 (6), 667-676, 2015 | 37 | 2015 |
Identification of novel targets of diabetic nephropathy and PEDF peptide treatment using RNA-seq A Rubin, AC Salzberg, Y Imamura, A Grivitishvilli, J Tombran-Tink BMC genomics 17, 1-17, 2016 | 36 | 2016 |
Activity-induced regulation of synaptic strength through the chromatin reader L3mbtl1 W Mao, AC Salzberg, M Uchigashima, Y Hasegawa, H Hock, ... Cell reports 23 (11), 3209-3222, 2018 | 34 | 2018 |
Effect of productive human papillomavirus 16 infection on global gene expression in cervical epithelium SD Kang, S Chatterjee, S Alam, AC Salzberg, J Milici, SH Van Der Burg, ... Journal of virology 92 (20), 10.1128/jvi. 01261-18, 2018 | 33 | 2018 |
Hypomethylated Fgf3 is a potential biomarker for early detection of oral cancer in mice treated with the tobacco carcinogen dibenzo[def,p]chrysene YW Sun, KM Chen, Y Imamura Kawasawa, AC Salzberg, TK Cooper, ... PLoS One 12 (10), e0186873, 2017 | 30 | 2017 |
Classification of alcohol abuse by plasma protein biomarkers WM Freeman, AC Salzberg, SW Gonzales, KA Grant, KE Vrana Biological psychiatry 68 (3), 219-222, 2010 | 29 | 2010 |
RNA-seq implicates deregulation of the immune system in the pathogenesis of diverticulitis KM Schieffer, CS Choi, S Emrich, L Harris, S Deiling, DM Karamchandani, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 313 (3 …, 2017 | 28 | 2017 |
O-GlcNAcylation alters the selection of mRNAs for translation and promotes 4E-BP1–dependent mitochondrial dysfunction in the retina SK Dierschke, WP Miller, JS Favate, P Shah, YI Kawasawa, AC Salzberg, ... Journal of Biological Chemistry 294 (14), 5508-5520, 2019 | 26 | 2019 |
Variations in brain defects result from cellular mosaicism in the activation of heat shock signalling S Ishii, M Torii, AI Son, M Rajendraprasad, YM Morozov, YI Kawasawa, ... Nature communications 8 (1), 15157, 2017 | 26 | 2017 |
RNA sequencing reveals a slow to fast muscle fiber type transition after olanzapine infusion in rats CJ Lynch, Y Xu, A Hajnal, AC Salzberg, YI Kawasawa PLoS One 10 (4), e0123966, 2015 | 26 | 2015 |