A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade DS Thommen, VH Koelzer, P Herzig, A Roller, M Trefny, S Dimeloe, ... Nature Medicine 24 (7), 994-1004, 2018 | 907 | 2018 |
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ... The Lancet Gastroenterology & Hepatology 1 (3), 207-216, 2016 | 293 | 2016 |
Tumor budding in colorectal cancer—ready for diagnostic practice? VH Koelzer, I Zlobec, A Lugli Human Pathology 47 (1), 4-19, 2016 | 288 | 2016 |
Two distinct immunopathological profiles in autopsy lungs of COVID-19 R Nienhold, Y Ciani, VH Koelzer, A Tzankov, JD Haslbauer, T Menter, ... Nature Communications 11 (1), 1-13, 2020 | 250 | 2020 |
Systemic inflammation in a melanoma patient treated with immune checkpoint inhibitors—an autopsy study VH Koelzer, SI Rothschild, D Zihler, A Wicki, B Willi, N Willi, M Voegeli, ... Journal for Immunotherapy of Cancer 4 (1), 1-8, 2016 | 196 | 2016 |
Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning K Sirinukunwattana, E Domingo, SD Richman, KL Redmond, A Blake, ... Gut 70 (3), 544-554, 2021 | 181 | 2021 |
Proposal for a 10-high-power-fields scoring method for the assessment of tumor budding in colorectal cancer E Karamitopoulou, I Zlobec, V Kölzer, A Kondi-Pafiti, ES Patsouris, ... Modern Pathology 26 (2), 295-301, 2013 | 165 | 2013 |
Tumor budding score based on 10 high-power fields is a promising basis for a standardized prognostic scoring system in stage II colorectal cancer M Horcic, VH Koelzer, E Karamitopoulou, L Terracciano, G Puppa, ... Human Pathology 44 (5), 697-705, 2013 | 159 | 2013 |
Tumor budding in colorectal cancer revisited: results of a multicenter interobserver study VH Koelzer, I Zlobec, MD Berger, G Cathomas, H Dawson, K Dirschmid, ... Virchows Archiv 466, 485-493, 2015 | 133 | 2015 |
Precision immunoprofiling by image analysis and artificial intelligence VH Koelzer, K Sirinukunwattana, J Rittscher, KD Mertz Virchows Archiv 474 (4), 511-522, 2019 | 131 | 2019 |
Phenotyping of tumor-associated macrophages in colorectal cancer: Impact on single cell invasion (tumor budding) and clinicopathological outcome VH Koelzer, K Canonica, H Dawson, L Sokol, ... Oncoimmunology 5 (4), e1106677, 2016 | 129 | 2016 |
CD103 is a hallmark of tumor‐infiltrating regulatory T cells D Anz, W Mueller, M Golic, WG Kunz, M Rapp, VH Koelzer, J Ellermeier, ... International journal of cancer 129 (10), 2417-2426, 2011 | 127 | 2011 |
The evolutionary landscape of colorectal tumorigenesis W Cross, M Kovac, V Mustonen, D Temko, H Davis, AM Baker, S Biswas, ... Nature Ecology & Evolution 2 (10), 1661-1672, 2018 | 114 | 2018 |
Tumor-associated macrophages and response to 5-fluorouracil adjuvant therapy in stage III colorectal cancer A Malesci, P Bianchi, G Celesti, G Basso, F Marchesi, F Grizzi, G Di Caro, ... Oncoimmunology 6 (12), e1342918, 2017 | 106 | 2017 |
Intratumoural budding (ITB) in preoperative biopsies predicts the presence of lymph node and distant metastases in colon and rectal cancer patients I Zlobec, M Hädrich, H Dawson, VH Koelzer, M Borner, M Mallaev, ... British Journal of Cancer 110 (4), 1008-1013, 2014 | 105 | 2014 |
The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice KD Mertz, LF Mager, MH Wasmer, T Thiesler, VH Koelzer, G Ruzzante, ... Oncoimmunology 5 (1), e1062966, 2016 | 100 | 2016 |
The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support A Irmisch, X Bonilla, S Chevrier, KV Lehmann, F Singer, NC Toussaint, ... Cancer Cell 39 (3), 288-293, 2021 | 92 | 2021 |
Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer M Lawler, D Alsina, RA Adams, AS Anderson, G Brown, NS Fearnhead, ... Gut 67 (1), 179-193, 2018 | 89 | 2018 |
Immunostimulatory RNA blocks suppression by regulatory T cells D Anz, VH Koelzer, S Moder, R Thaler, T Schwerd, K Lahl, T Sparwasser, ... The Journal of Immunology 184 (2), 939-946, 2010 | 87 | 2010 |
Mitosis domain generalization in histopathology images -- The MIDOG challenge M Aubreville, N Stathonikos, CA Bertram, R Klopleisch, N ter Hoeve, ... arXiv preprint arXiv:2204.03742, 2022 | 86 | 2022 |