Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis AHA Clayton, F Walker, SG Orchard, C Henderson, D Fuchs, J Rothacker, ... Journal of Biological Chemistry 280 (34), 30392-30399, 2005 | 321 | 2005 |
Graphical representation and multicomponent analysis of single‐frequency fluorescence lifetime imaging microscopy data AHA Clayton, QS Hanley, PJ Verveer Journal of microscopy 213 (1), 1-5, 2004 | 283 | 2004 |
Dynamic fluorescence anisotropy imaging microscopy inthe frequency domain (rFLIM) AHA Clayton, QS Hanley, DJ Arndt-Jovin, V Subramaniam, TM Jovin Biophysical journal 83 (3), 1631-1649, 2002 | 256 | 2002 |
The preparation of colloidally stable, water-soluble, biocompatible, semiconductor nanocrystals with a small hydrodynamic diameter EE Lees, TL Nguyen, AHA Clayton, P Mulvaney ACS nano 3 (5), 1121-1128, 2009 | 232 | 2009 |
Imaging molecular interactions in cells by dynamic and static fluorescence anisotropy (rFLIM and emFRET) DS Lidke, P Nagy, BG Barisas, R Heintzmann, JN Post, KA Lidke, ... Biochemical society transactions 31 (5), 1020-1027, 2003 | 196 | 2003 |
EGFR oligomerization organizes kinase-active dimers into competent signalling platforms SR Needham, SK Roberts, A Arkhipov, VP Mysore, CJ Tynan, ... Nature communications 7 (1), 13307, 2016 | 171 | 2016 |
Targeting of a conformationally exposed, tumor-specific epitope of EGFR as a strategy for cancer therapy HK Gan, AW Burgess, AHA Clayton, AM Scott Cancer research 72 (12), 2924-2930, 2012 | 165 | 2012 |
Spectral properties of fluorescein in solvent‐water mixtures: applications as a probe of hydrogen bonding environments in biological systems N Klonis, AHA Clayton, EW Voss Jr, WH Sawyer Photochemistry and photobiology 67 (5), 500-510, 1998 | 156 | 1998 |
A SOX9 defect of calmodulin-dependent nuclear import in campomelic dysplasia/autosomal sex reversal A Argentaro, H Sim, S Kelly, S Preiss, A Clayton, DA Jans, VR Harley Journal of Biological Chemistry 278 (36), 33839-33847, 2003 | 147 | 2003 |
The influence of nanostructured materials on biointerfacial interactions P Koegler, A Clayton, H Thissen, GNC Santos, P Kingshott Advanced drug delivery reviews 64 (15), 1820-1839, 2012 | 139 | 2012 |
Experimental determination of quantum dot size distributions, ligand packing densities, and bioconjugation using analytical ultracentrifugation EE Lees, MJ Gunzburg, TL Nguyen, GJ Howlett, J Rothacker, EC Nice, ... Nano letters 8 (9), 2883-2890, 2008 | 124 | 2008 |
Enumeration of oligomerization states of membrane proteins in living cells by homo-FRET spectroscopy and microscopy: theory and application EKL Yeow, AHA Clayton Biophysical journal 92 (9), 3098-3104, 2007 | 116 | 2007 |
Organization of higher-order oligomers of the serotonin1A receptor explored utilizing homo-FRET in live cells S Ganguly, AHA Clayton, A Chattopadhyay Biophysical journal 100 (2), 361-368, 2011 | 114 | 2011 |
Compound effects of point mutations causing campomelic dysplasia/autosomal sex reversal upon SOX9 structure, nuclear transport, DNA binding, and transcriptional activation S Preiss, A Argentaro, A Clayton, A John, DA Jans, T Ogata, T Nagai, ... Journal of Biological Chemistry 276 (30), 27864-27872, 2001 | 111 | 2001 |
Antibodies specifically targeting a locally misfolded region of tumor associated EGFR TPJ Garrett, AW Burgess, HK Gan, RB Luwor, G Cartwright, F Walker, ... Proceedings of the National Academy of Sciences 106 (13), 5082-5087, 2009 | 108 | 2009 |
Imaging the action of antimicrobial peptides on living bacterial cells ML Gee, M Burton, A Grevis-James, MA Hossain, S McArthur, ... Scientific reports 3 (1), 1557, 2013 | 107 | 2013 |
Unligated epidermal growth factor receptor forms higher order oligomers within microclusters on A431 cells that are sensitive to tyrosine kinase inhibitor binding AHA Clayton, ML Tavarnesi, TG Johns Biochemistry 46 (15), 4589-4597, 2007 | 101 | 2007 |
Through-Bond and Through-Space Coupling in Photoinduced Electron and Energy Transfer: An ab Initio and Semiempirical Study AHA Clayton, GD Scholes, KP Ghiggino, MN Paddon-Row The Journal of Physical Chemistry 100 (26), 10912-10918, 1996 | 99 | 1996 |
Predominance of activated EGFR higher-order oligomers on the cell surface AHA Clayton, SG Orchard, EC Nice, RG Posner, AW Burgess Growth Factors 26 (6), 316-324, 2008 | 93 | 2008 |
Exploring higher-order EGFR oligomerisation and phosphorylation—a combined experimental and theoretical approach N Kozer, D Barua, S Orchard, EC Nice, AW Burgess, WS Hlavacek, ... Molecular BioSystems 9 (7), 1849-1863, 2013 | 86 | 2013 |