CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ... Molecular cell 46 (5), 595-605, 2012 | 741 | 2012 |
The role of nucleoid‐associated proteins in the organization and compaction of bacterial chromatin RT Dame Molecular microbiology 56 (4), 858-870, 2005 | 477 | 2005 |
Bacterial chromatin organization by H-NS protein unravelled using dual DNA manipulation RT Dame, MC Noom, GJL Wuite Nature 444 (7117), 387-390, 2006 | 447 | 2006 |
Dual architectural roles of HU: formation of flexible hinges and rigid filaments J van Noort, S Verbrugge, N Goosen, C Dekker, RT Dame Proceedings of the National Academy of Sciences 101 (18), 6969-6974, 2004 | 364 | 2004 |
H-NS mediated compaction of DNA visualised by atomic force microscopy RT Dame, C Wyman, N Goosen Nucleic acids research 28 (18), 3504-3510, 2000 | 359 | 2000 |
The architectural role of nucleoid-associated proteins in the organization of bacterial chromatin: a molecular perspective MS Luijsterburg, MC Noom, GJL Wuite, RT Dame Journal of structural biology 156 (2), 262-272, 2006 | 329 | 2006 |
Moltemplate: A tool for coarse-grained modeling of complex biological matter and soft condensed matter physics AI Jewett, D Stelter, J Lambert, SM Saladi, OM Roscioni, M Ricci, L Autin, ... Journal of molecular biology 433 (11), 166841, 2021 | 290 | 2021 |
The major architects of chromatin: architectural proteins in bacteria, archaea and eukaryotes MS Luijsterburg, MF White, R Van Driel, RT Dame Critical reviews in biochemistry and molecular biology 43 (6), 393-418, 2008 | 273 | 2008 |
Structural basis for H-NS-mediated trapping of RNA polymerase in the open initiation complex at the rrnB P1 RT Dame, C Wyman, R Wurm, R Wagner, N Goosen Journal of Biological Chemistry 277 (3), 2146-2150, 2002 | 229 | 2002 |
Chromosome organization in bacteria: mechanistic insights into genome structure and function RT Dame, FZM Rashid, DC Grainger Nature Reviews Genetics 21 (4), 227-242, 2020 | 191 | 2020 |
DNA bridging: a property shared among H-NS-like proteins RT Dame, MS Luijsterburg, E Krin, PN Bertin, R Wagner, GJL Wuite Journal of bacteriology 187 (5), 1845-1848, 2005 | 175 | 2005 |
HU: promoting or counteracting DNA compaction? RT Dame, N Goosen FEBS letters 529 (2-3), 151-156, 2002 | 155 | 2002 |
Chromosomal macrodomains and associated proteins: implications for DNA organization and replication in gram negative bacteria RT Dame, OJ Kalmykowa, DC Grainger PLoS genetics 7 (6), e1002123, 2011 | 134 | 2011 |
Structural basis for preferential binding of H-NS to curved DNA RT Dame, C Wyman, N Goosen Biochimie 83 (2), 231-234, 2001 | 134 | 2001 |
H-NS promotes looped domain formation in the bacterial chromosome MC Noom, WW Navarre, T Oshima, GJL Wuite, RT Dame Current Biology 17 (21), R913-R914, 2007 | 122 | 2007 |
The interplay between nucleoid organization and transcription in archaeal genomes E Peeters, RPC Driessen, F Werner, RT Dame Nature Reviews Microbiology 13 (6), 333-341, 2015 | 121 | 2015 |
dCas9: a versatile tool for epigenome editing DJW Brocken, M Tark-Dame, RT Dame Current issues in molecular biology 26 (1), 15-32, 2018 | 120 | 2018 |
Alba shapes the archaeal genome using a delicate balance of bridging and stiffening the DNA N Laurens, RPC Driessen, I Heller, D Vorselen, MC Noom, FJH Hol, ... Nature communications 3 (1), 1328, 2012 | 113 | 2012 |
Structure and function of archaeal histones B Henneman, C Van Emmerik, T Brouwer, RA Van der Valk, N Kirolos, ... PLOS Genetics 14 (9), e1007582, 2018 | 107 | 2018 |
Effect of temperature on the intrinsic flexibility of DNA and its interaction with architectural proteins RPC Driessen, G Sitters, N Laurens, GF Moolenaar, GJL Wuite, N Goosen, ... Biochemistry 53 (41), 6430-6438, 2014 | 104 | 2014 |