Biosynthesis of the Arabinogalactan‐Peptidoglycan Complex of Mycobacterium tuberculosiss DC Crick, PJ Brennan The mycobacterial cell envelope, 25-40, 2008 | 385 | 2008 |
Phosphatidylinositol is an essential phospholipid of mycobacteria M Jackson, DC Crick, PJ Brennan Journal of Biological Chemistry 275 (39), 30092-30099, 2000 | 273 | 2000 |
Multitarget drug discovery for tuberculosis and other infectious diseases K Li, LA Schurig-Briccio, X Feng, A Upadhyay, V Pujari, B Lechartier, ... Journal of medicinal chemistry 57 (7), 3126-3139, 2014 | 258 | 2014 |
Identification of the namH gene, encoding the hydroxylase responsible for the N-glycolylation of the mycobacterial peptidoglycan JB Raymond, S Mahapatra, DC Crick, MS Pavelka Journal of Biological Chemistry 280 (1), 326-333, 2005 | 251 | 2005 |
Decaprenylphosphoryl Arabinofuranose, the Donor of the d-Arabinofuranosyl Residues of Mycobacterial Arabinan, Is Formed via a Two-Step Epimerization of … K Mikušová, H Huang, T Yagi, M Holsters, D Vereecke, W D'Haeze, ... Journal of bacteriology 187 (23), 8020-8025, 2005 | 250 | 2005 |
Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis W Li, A Upadhyay, FL Fontes, EJ North, Y Wang, DC Crans, ... Antimicrobial agents and chemotherapy 58 (11), 6413-6423, 2014 | 225 | 2014 |
Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis B Phetsuksiri, M Jackson, H Scherman, M McNeil, GS Besra, AR Baulard, ... Journal of Biological Chemistry 278 (52), 53123-53130, 2003 | 208 | 2003 |
The cell-wall core of Mycobacterium tuberculosis in the context of drug discovery. PJ Brennan, DC Crick Current topics in medicinal chemistry 7 (5), 475-488, 2007 | 201 | 2007 |
Antiinfectives targeting enzymes and the proton motive force X Feng, W Zhu, LA Schurig-Briccio, S Lindert, C Shoen, R Hitchings, J Li, ... Proceedings of the National Academy of Sciences 112 (51), E7073-E7082, 2015 | 197 | 2015 |
A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria CL Gee, KG Papavinasasundaram, SR Blair, CE Baer, AM Falick, ... Science signaling 5 (208), ra7-ra7, 2012 | 189 | 2012 |
Novel salvage pathway utilizing farnesol and geranylgeraniol for protein isoprenylation. DC Crick, DA Andres, CJ Waechter Biochemical and biophysical research communications 237 (3), 483-487, 1997 | 172 | 1997 |
Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non‐replicating persistence RK Dhiman, S Mahapatra, RA Slayden, ME Boyne, A Lenaerts, ... Molecular microbiology 72 (1), 85-97, 2009 | 170 | 2009 |
Lipidomic analyses of Mycobacterium tuberculosis based on accurate mass measurements and the novel “Mtb LipidDB”[S] MJ Sartain, DL Dick, CD Rithner, DC Crick, JT Belisle Journal of lipid research 52 (5), 861-872, 2011 | 164 | 2011 |
Export-mediated assembly of mycobacterial glycoproteins parallels eukaryotic pathways BC VanderVen, JD Harder, DC Crick, JT Belisle Science 309 (5736), 941-943, 2005 | 162 | 2005 |
Biosynthesis of the galactan component of the mycobacterial cell wall K Mikušová, T Yagi, R Stern, MR McNeil, GS Besra, DC Crick, ... Journal of Biological Chemistry 275 (43), 33890-33897, 2000 | 160 | 2000 |
Targeting the formation of the cell wall core of M. tuberculosis CE Barry, DC Crick, MR McNeil Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2007 | 156 | 2007 |
Inhibition of the first step in synthesis of the mycobacterial cell wall core, catalyzed by the GlcNAc-1-phosphate transferase WecA, by the novel caprazamycin derivative CPZEN-45 Y Ishizaki, C Hayashi, K Inoue, M Igarashi, Y Takahashi, V Pujari, ... Journal of Biological Chemistry 288 (42), 30309-30319, 2013 | 148 | 2013 |
Metabolic Profiling of Lung Granuloma in Mycobacterium tuberculosis Infected Guinea Pigs: Ex vivo 1H Magic Angle Spinning NMR Studies BS Somashekar, AG Amin, CD Rithner, JL Troudt, R Basaraba, A Izzo, ... Journal of proteome research 10 (9), 4186-4195, 2011 | 139 | 2011 |
Discovery of selective menaquinone biosynthesis inhibitors against Mycobacterium tuberculosis J Debnath, S Siricilla, B Wan, DC Crick, AJ Lenaerts, SG Franzblau, ... Journal of medicinal chemistry 55 (8), 3739-3755, 2012 | 138 | 2012 |
Ppm1, a novel polyprenol monophosphomannose synthase from Mycobacterium tuberculosis SS Gurcha, AR Baulard, L Kremer, C Locht, DB Moody, W Muhlecker, ... Biochemical Journal 365 (2), 441-450, 2002 | 132 | 2002 |