Potent α-synuclein aggregation inhibitors, identified by high-throughput screening, mainly target the monomeric state M Kurnik, C Sahin, CB Andersen, N Lorenzen, L Giehm, ... Cell chemical biology 25 (11), 1389-1402. e9, 2018 | 79 | 2018 |
Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity H Mohammad-Beigi, F Aliakbari, C Sahin, C Lomax, A Tawfike, ... Journal of Biological Chemistry 294 (11), 4215-4232, 2019 | 71 | 2019 |
Mechanistic understanding of the interactions between nano-objects with different surface properties and α-synuclein H Mohammad-Beigi, A Hosseini, M Adeli, MR Ejtehadi, G Christiansen, ... ACS nano 13 (3), 3243-3256, 2019 | 53 | 2019 |
A mass‐spectrometry‐based approach to distinguish annular and specific lipid binding to membrane proteins JR Bolla, RA Corey, C Sahin, J Gault, A Hummer, JTS Hopper, DP Lane, ... Angewandte Chemie 132 (9), 3551-3556, 2020 | 41 | 2020 |
Antibodies against the C-terminus of α-synuclein modulate its fibrillation C Sahin, N Lorenzen, L Lemminger, G Christiansen, IM Møller, ... Biophysical chemistry 220, 34-41, 2017 | 34 | 2017 |
Scratching the surface: native mass spectrometry of peripheral membrane protein complexes C Sahin, DJ Reid, MT Marty, M Landreh Biochemical Society Transactions 48 (2), 547-558, 2020 | 30 | 2020 |
Predicting the shapes of protein complexes through collision cross section measurements and database searches M Landreh, C Sahin, J Gault, S Sadeghi, CL Drum, P Uzdavinys, D Drew, ... Analytical Chemistry 92 (18), 12297-12303, 2020 | 27 | 2020 |
Early events in copper-ion catalyzed oxidation of α-synuclein MK Tiwari, F Leinisch, C Sahin, IM Møller, DE Otzen, MJ Davies, ... Free Radical Biology and Medicine 121, 38-50, 2018 | 25 | 2018 |
Order and disorder—An integrative structure of the full-length human growth hormone receptor N Kassem, R Araya-Secchi, K Bugge, A Barclay, H Steinocher, ... Science Advances 7 (27), eabh3805, 2021 | 24 | 2021 |
Gas-Phase Collisions with Trimethylamine-N-Oxide Enable Activation-Controlled Protein Ion Charge Reduction M Kaldmäe, N Österlund, D Lianoudaki, C Sahin, P Bergman, T Nyman, ... Journal of The American Society for Mass Spectrometry 30 (8), 1385-1388, 2019 | 22 | 2019 |
α-Synucleins from animal species show low fibrillation propensities and weak oligomer membrane disruption C Sahin, L Kjær, MS Christensen, J N. Pedersen, G Christiansen, ... Biochemistry 57 (34), 5145-5158, 2018 | 20 | 2018 |
High intracellular stability of the spidroin N‐terminal domain in spite of abundant amyloidogenic segments revealed by in‐cell hydrogen/deuterium exchange mass spectrometry M Kaldmäe, A Leppert, G Chen, M Sarr, C Sahin, K Nordling, N Kronqvist, ... The FEBS Journal 287 (13), 2823-2833, 2020 | 19 | 2020 |
A strategy for the identification of protein architectures directly from ion mobility mass spectrometry data reveals stabilizing subunit interactions in light harvesting complexes M Kaldmäe, C Sahin, M Saluri, EG Marklund, M Landreh Protein Science 28 (6), 1024-1030, 2019 | 19 | 2019 |
Charge engineering reveals the roles of ionizable side chains in electrospray ionization mass spectrometry ML Abramsson, C Sahin, JTS Hopper, RMM Branca, J Danielsson, M Xu, ... JACS Au 1 (12), 2385-2393, 2021 | 18 | 2021 |
Liquid–liquid phase separation primes spider silk proteins for fiber formation via a conditional sticker domain A Leppert, G Chen, D Lama, C Sahin, V Railaite, O Shilkova, T Arndt, ... Nano Letters 23 (12), 5836-5841, 2023 | 17 | 2023 |
Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform T Arndt, K Jaudzems, O Shilkova, J Francis, M Johansson, PR Laity, ... Nature Communications 13 (1), 4695, 2022 | 13 | 2022 |
Mass spectrometry of RNA-binding proteins during liquid–liquid phase separation reveals distinct assembly mechanisms and droplet architectures C Sahin, A Motso, X Gu, H Feyrer, D Lama, T Arndt, A Rising, GV Gese, ... Journal of the American Chemical Society 145 (19), 10659-10668, 2023 | 11 | 2023 |
Structural basis for dityrosine-mediated inhibition of α-synuclein fibrillization C Sahin, EC Østerlund, N Österlund, J Costeira-Paulo, JN Pedersen, ... Journal of the American Chemical Society 144 (27), 11949-11954, 2022 | 10 | 2022 |
The changing face of aging: highly sulfated glycosaminoglycans induce amyloid formation in a lattice corneal dystrophy model protein KG Malmos, M Stenvang, C Sahin, G Christiansen, DE Otzen Journal of Molecular Biology 429 (18), 2755-2764, 2017 | 10 | 2017 |
Mass spectrometry and machine learning reveal determinants of client recognition by antiamyloid chaperones N Österlund, T Vosselman, A Leppert, A Gräslund, H Jörnvall, LL Ilag, ... Molecular & Cellular Proteomics 21 (10), 2022 | 9 | 2022 |