Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells J Krönke, ND Udeshi, A Narla, P Grauman, SN Hurst, M McConkey, ... Science 343 (6168), 301-305, 2014 | 1685 | 2014 |
IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 … P Paschka, RF Schlenk, VI Gaidzik, M Habdank, J Kronke, L Bullinger, ... J Clin Oncol 28 (22), 3636-3643, 2010 | 1002 | 2010 |
Lenalidomide induces ubiquitination and degradation of CK1α in del (5q) MDS J Krönke, EC Fink, PW Hollenbach, KJ MacBeth, SN Hurst, ND Udeshi, ... Nature 523 (7559), 183-188, 2015 | 823 | 2015 |
Monitoring of Minimal Residual Disease in NPM1-Mutated Acute Myeloid Leukemia: A Study From the German-Austrian Acute Myeloid Leukemia Study Group J Krönke, RF Schlenk, KO Jensen, F Tschürtz, A Corbacioglu, VI Gaidzik, ... Journal of Clinical Oncology 29 (19), 2709-2716, 2011 | 484 | 2011 |
Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia J Krönke, L Bullinger, V Teleanu, F Tschürtz, VI Gaidzik, MWM Kühn, ... Blood, The Journal of the American Society of Hematology 122 (1), 100-108, 2013 | 313 | 2013 |
Anti–B-cell maturation antigen BiTE molecule AMG 420 induces responses in multiple myeloma MS Topp, J Duell, G Zugmaier, M Attal, P Moreau, C Langer, J Krönke, ... Journal of Clinical Oncology 38 (8), 775-783, 2020 | 279 | 2020 |
Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs J Kronke, R Kittler, F Buchholz, MP Windisch, T Pietschmann, ... Journal of virology 78 (7), 3436-3446, 2004 | 243 | 2004 |
Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing A Dolnik, JC Engelmann, M Scharfenberger-Schmeer, J Mauch, ... Blood, The Journal of the American Society of Hematology 120 (18), e83-e92, 2012 | 178 | 2012 |
Identification of acquired copy number alterations and uniparental disomies in cytogenetically normal acute myeloid leukemia using high-resolution single-nucleotide … L Bullinger, J Krönke, C Schön, I Radtke, K Urlbauer, U Botzenhardt, ... Leukemia 24 (2), 438-449, 2010 | 157 | 2010 |
Homo-PROTACs for the chemical knockdown of cereblon C Steinebach, S Lindner, ND Udeshi, DC Mani, H Kehm, S Köpff, ... ACS chemical biology 13 (9), 2771-2782, 2018 | 135 | 2018 |
Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation S Cocciardi, A Dolnik, S Kapp-Schwoerer, FG Rücker, S Lux, TJ Blätte, ... Nature Communications 10 (1), 2031, 2019 | 112 | 2019 |
Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders C Steinebach, YLD Ng, I Sosič, CS Lee, S Chen, S Lindner, LP Vu, ... Chemical science 11 (13), 3474-3486, 2020 | 97 | 2020 |
PROTAC-mediated crosstalk between E3 ligases C Steinebach, H Kehm, S Lindner, LP Vu, S Köpff, ÁL Mármol, C Weiler, ... Chemical communications 55 (12), 1821-1824, 2019 | 94 | 2019 |
High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations MWM Kühn, I Radtke, L Bullinger, S Goorha, J Cheng, J Edelmann, ... Blood, The Journal of the American Society of Hematology 119 (10), e67-e75, 2012 | 93 | 2012 |
Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial S Kapp-Schwoerer, D Weber, A Corbacioglu, VI Gaidzik, P Paschka, ... Blood, The Journal of the American Society of Hematology 136 (26), 3041-3050, 2020 | 89 | 2020 |
Lenalidomide induces degradation of IKZF1 and IKZF3 J Krönke, SN Hurst, BL Ebert Oncoimmunology 3 (7), e941742, 2014 | 78 | 2014 |
Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia S Hirsch, TJ Blätte, S Grasedieck, S Cocciardi, A Rouhi, ... haematologica 102 (12), 2039, 2017 | 75 | 2017 |
Comparison between 5-azacytidine treatment and allogeneic stem-cell transplantation in elderly patients with advanced MDS according to donor availability (VidazaAllo Study) N Kröger, K Sockel, C Wolschke, W Bethge, RF Schlenk, D Wolf, ... Journal of Clinical Oncology 39 (30), 3318-3327, 2021 | 67 | 2021 |
DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia VI Gaidzik, D Weber, P Paschka, A Kaumanns, S Krieger, A Corbacioglu, ... Leukemia 32 (1), 30-37, 2018 | 65 | 2018 |
The molecular mechanism of thalidomide analogs in hematologic malignancies S Lindner, J Krönke Journal of molecular medicine 94 (12), 1327-1334, 2016 | 57 | 2016 |